MNI-caged-L-glutamate
Tocris Bioscience a Bio-Techne Brand
Key Product Details
Description: | Stable photoreleaser of L-glutamate |
Alternative Names: | 4-Methoxy-7-nitroindolinyl-caged-L-glutamate, MNI glutamate |
Chemical Name: | (S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 323.3 |
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Citations for MNI-caged-L-glutamate (61)
Citations are publications that use Bio-Techne products. Selected citations for MNI-caged-L-glutamate include:
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Wu et al.
(2021)
Ketamine Rapidly Enhances Glutamate-Evoked Dendritic Spinogenesis in Medial Prefrontal Cortex Through Dopaminergic Mechanisms
Biol.Psychiatry.
89:1096
PMID: 33637303 -
Nuno-Perez
(2021)
Stress undermines reward-guided cognitive performance through synaptic depression in the lateral habenula
Neuron.
109:947
PMID: 33535028 -
Otopalik et al.
(2019)
Neuronal morphologies built for reliable physiology in a rhythmic motor circuit.
Elife.
8
PMID: 30657452 -
Obashi et al.
(2019)
Precise Temporal Regulation of Molecular Diffusion within Dendritic Spines by Actin Polymers during Structural Plasticity.
Cell Rep.
27:1503
PMID: 31042476 -
Tazerart et al.
(2019)
Spike-timing-dependent plasticity rule for single, clustered and distributed dendritic spines.
Nat Commun.
11:4276
PMID: 32848151 -
Mitchell et al.
(2019)
Probing Single Synapses via the Photolytic Release of Neurotransmitters
Front Synaptic Neurosci.
11
PMID: 31354469 -
Incontro
(2018)
The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms.
Nat Commun.
9:2069
PMID: 29802289 -
Xiao et al.
(2018)
OXT functions as a spatiotemporal filter for excitatory synaptic inputs to VTA DA neurons.
Elife.
7
PMID: 29676731 -
Hangen et al.
(2018)
Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR.
Cell Rep.
24:1001
PMID: 30044968 -
Chopek et al.
(2018)
Sub-populations of Spinal V3 Interneurons Form Focal Modules of Layered Pre-motor Microcircuits.
Cell Rep.
25:146
PMID: 30282024 -
Cheriyan and Sheets
(2018)
Altered Excitability and Local Connectivity of mPFC-PAG Neurons in a Mouse Model of Neuropathic Pain.
J Neurosci.
38:4829
PMID: 29695413 -
Kiragasi et al.
(2017)
A Presynaptic Glutamate Receptor Subunit Confers Robustness to Neurotransmission and Homeostatic Potentiation.
Cell Rep.
19:2694
PMID: 28658618 -
Goo et al.
(2017)
Activity-dependent trafficking of lysosomes in dendrites and dendritic spines.
J Cell Biol.
216:2499
PMID: 28630145 -
Athilingam et al.
(2017)
Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons.
Elife.
6
PMID: 29206101 -
Sigler et al.
(2017)
Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.
Neuron.
94:304
PMID: 28426965 -
Otopalik et al.
(2017)
When complex neuronal structures may not matter.
Elife.
6
PMID: 28165322 -
Chang et al.
(2017)
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca2+ Signals during LTP Induction, but Not Maintenance.
Neuron.
94:800
PMID: 28521133 -
Lu et al.
(2017)
Slow AMPAR Synaptic Transmission Is Determined by Stargazin and Glutamate Transporters.
Neuron.
96:73
PMID: 28919175 -
Zhang et al.
(2016)
Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors.
Nat.Commun..
7:12650
PMID: 27586999 -
Berlin et al.
(2016)
A family of photoswitchable NMDA receptors.
Elife.
5
PMID: 26929991 -
Oberlander
(2016)
17β-OEAcutely Potentiates Glutamatergic Synaptic Transmission in the Hippocampus through Distinct Mechanisms in Males and Females.
J Neurosci.
36:2677
PMID: 26937008 -
Nygaard et al.
(2015)
Melanoma brain colonization involves the emergence of a brain-adaptive phenotype.
J Neurosci.
1:82
PMID: 25593989 -
Harnett et al.
(2015)
Distribution and function of HCN channels in the apical dendritic tuft of neocortical pyramidal neurons.
PLoS One.
35:1024
PMID: 25609619 -
Erlandson et al.
(2015)
The Functional Organization of Neocortical Networks Investigated in Slices with Local Field Recordings and Laser Scanning Photostimulation.
Front Cell Neurosci.
10:e0132008
PMID: 26134668 -
Ferreira et al.
(2015)
Highly differentiated cellular and circuit properties of infralimbic pyramidal neurons projecting to the periaqueductal gray and amygdala.
Nat Commun.
9:161
PMID: 25972785 -
Laprell et al.
(2015)
Optical control of NMDA receptors with a diffusible photoswitch.
PLoS One.
6:8076
PMID: 26311290 -
Otmakhov et al.
(2015)
Fast Decay of CaMKII FRET Sensor Signal in Spines after LTP Induction Is Not Due to Its Dephosphorylation.
Front Cell Neurosci.
10:e0130457
PMID: 26086939 -
Yang et al.
(2015)
The Shaping of Two Distinct Dendritic Spikes by A-Type Voltage-Gated K(+) Channels.
J Neurosci.
9:469
PMID: 26696828 -
Goddard et al.
(2014)
Spatially reciprocal inhibition of inhibition within a stimulus selection network in the avian midbrain.
PLoS One.
9:e85865
PMID: 24465755 -
Ikrar et al.
(2014)
Adult neurogenesis modifies excitability of the dentate gyrus.
Front Neural Circuits.
7:204
PMID: 24421758 -
Kamijo et al.
(2014)
Input integration around the dendritic branches in hippocampal dentate granule cells.
Cogn Neurodyn.
8:267
PMID: 25009669 -
Stephany et al.
(2014)
Plasticity of binocularity and visual acuity are differentially limited by nogo receptor.
J Neurosci.
34:11631
PMID: 25164659 -
Go et al.
(2013)
Four-dimensional multi-site photolysis of caged neurotransmitters.
Front Cell Neurosci.
7:231
PMID: 24348330 -
Turesson et al.
(2013)
Intrinsic connections in the anterior part of the bed nucleus of the stria terminalis.
J Neurophysiol.
109:2438
PMID: 23446692 -
Li et al.
(2013)
Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus.
Proc Natl Acad Sci U S A.
110:9106
PMID: 23671081 -
Abbas et al.
(2013)
Directional summation in non-direction selective retinal ganglion cells.
PLoS Comput Biol.
9:e1002969
PMID: 23516351 -
Apostolides and Trussell
(2013)
Rapid, activity-independent turnover of vesicular transmitter content at a mixed glycine/GABA synapse.
J Neurosci.
33:4768
PMID: 23486948 -
Callender et al.
(2012)
Mechanism of inhibition of the glutamate transporter EAAC1 by the conformationally constrained glutamate analogue (+)-HIP-B.
Biochemistry.
51:5486
PMID: 22703277 -
Ferrario et al.
(2012)
Withdrawal from cocaine self-administration alters NMDA receptor-mediated Ca2+ entry in nucleus accumbens dendritic spines.
PLoS One.
7:e40898
PMID: 22870207 -
Zhang et al.
(2012)
Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy.
J Neurosci.
32:1183
PMID: 22279204 -
Dubos et al.
(2012)
Alteration of synaptic network dynamics by the intellectual disability protein PAK3.
J Neurosci.
32:519
PMID: 22238087 -
Doretto et al.
(2011)
Oligodendrocytes as regulators of neuronal networks during early postnatal development.
PLoS One.
6:e19849
PMID: 21589880 -
Davison and Ehlers
(2011)
Neural circuit mechanisms for pattern detection and feature combination in olfactory cortex.
Neuron.
70:82
PMID: 21482358 -
Vandenberg et al.
(2011)
Water and urea permeation pathways of the human excitatory amino acid transporter EAAT1.
Biochem J.
439:333
PMID: 21732909 -
Biase et al.
(2011)
NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.
Oncoscience.
31:12650
PMID: 21880926 -
Nothmann et al.
(2011)
Hetero-oligomerization of neuronal glutamate transporters.
J Neurosci.
286:3935
PMID: 21127051 -
Tao et al.
(2010)
Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101.
J Biol Chem.
285:17725
PMID: 20378543 -
Hammond et al.
(2010)
Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology.
ACS Chem Neurosci.
1:702
PMID: 20981342 -
Xu et al.
(2010)
High precision and fast functional mapping of cortical circuitry through a novel combination of voltage sensitive dye imaging and laser scanning photostimulation.
J Neurophysiol.
103:2301
PMID: 20130040 -
Earls et al.
(2010)
Dysregulation of presynaptic calcium and synaptic plasticity in a mouse model of 22q11 deletion syndrome.
J Biol Chem.
30:15843
PMID: 21106823 -
Brill and Huguenard
(2009)
Robust short-latency perisomatic inhibition onto neocortical pyramidal cells detected by laser-scanning photostimulation.
J Neurosci.
29:7413
PMID: 19515909 -
Holbro et al.
(2009)
Differential distribution of endoplasmic reticulum controls metabotropic signaling and plasticity at hippocampal synapses.
Proc Natl Acad Sci U S A.
106:15055
PMID: 19706463 -
Nikolenko et al.
(2009)
SLM Microscopy: Scanless Two-Photon Imaging and Photostimulation with Spatial Light Modulators.
Front Neural Circuits.
2:5
PMID: 19129923 -
Wood et al.
(2009)
Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiency.
Proc Natl Acad Sci U S A.
29:12440
PMID: 19812320 -
Brill and Huguenard
(2008)
Sequential changes in AMPA receptor targeting in the developing neocortical excitatory circuit.
J Reprod Dev.
28:13918
PMID: 19091980 -
Shankar et al.
(2007)
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway.
J Neurosci.
27:2866
PMID: 17360908 -
Tao et al.
(2006)
Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1.
J Biol Chem.
281:10263
PMID: 16478724 -
Araya et al.
(2006)
Dendritic spines linearize the summation of excitatory potentials.
Proc Natl Acad Sci U S A.
103:18799
PMID: 17132736 -
El-Kouhen et al.
(2006)
Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.
Br J Pharmacol.
149:761
PMID: 17016515 -
Araya et al.
(2006)
The spine neck filters membrane potentials.
J Neurosci.
103:17961
PMID: 17093040 -
Huang et al.
(2004)
Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons.
J Neurosci.
24:4551
PMID: 15140926
There are no citations that match your criteria.
Customer Reviews for MNI-caged-L-glutamate (1)
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Assay Type: In VitroCell Line/Tissue: Organotypic Hippocampus SlicesWe buy this product in bulk for use in all of our uncaging experiments. High frequency uncaging next to dendritic spine head induces reliable spine growth, indicative of synapse strengthening.We resuspend in ACSF and found that we can freeze and reuse the solution. However, when suspended in HBSS it is no longer effective after freezing.
There are no reviews that match your criteria.