(RS)-3,5-DHPG

Citations are publications that use Bio-Techne products. Selected citations for (RS)-3,5-DHPG include:

• Wall et al. (2018) The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. Neuron. 98:1124
  PMID: 29861284
• Lim et al. (2018) Neuronal Activity-Dependent Activation of Astroglial Calcineurin in Mouse Primary Hippocampal Cultures. Int J Mol Sci. 19
  PMID: 30274399
• Yasuda et al. (2018) Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction. Front Cell Neurosci. 12:330
  PMID: 30349460
• Vergassola et al. (2018) Presynaptic mGlu1 Receptors Control GABAB Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings. Front Mol Neurosci. 11:324
  PMID: 30279647
• Xi (2017) Metabotropic glutamate receptor 5 mediates the suppressive effect of 6-OHDA-induced model of Parkinson's disease on liver cancer. Pharmacol Res. 121:145
  PMID: 28455267
• Wang et al. (2017) Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism. J Clin Invest. 127:1978
  PMID: 28414301
• Levenga et al. (2017) AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity. Elife. 6
  PMID: 29173281
• Chai et al. (2017) Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 95:531
  PMID: 28712653
• Romei et al. (2016) Colocalization of neurotransmitter transporters on the plasma membrane of the same nerve terminal may reflect cotransmission. Brain Research Bulletin. 127:100
  PMID: 27565422
• Lin et al. (2016) Neuronal splicing regulator RBFOX3(NeuN) regulates adult hippocampal neurogenesis and synaptogenesis PLoS One. 11:e0164164
  PMID: 27701470
• Guo et al. (2016) Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice. J Neurosci. 36:2131
  PMID: 26888925
• Sethna et al. (2016) Calmodulin activity regulates group I metabotropic glutamate receptor-mediated signal transduction and synaptic depression. J Neurosci Res. 94:401
  PMID: 26864654
• Nonobe et al. (2016) Application of surface plasmon resonance imaging to monitoring G protein-coupled receptor signaling and its modulation in a heterologous expression system. BMC Biotechnol. 16:36
  PMID: 27068216
• Zhong et al. (2015) BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain DA neurons. Sci Rep. 35:4469
  PMID: 25762688
• Hasegawa et al. (2015) Dendritic spine dynamics leading to spine elimination after repeated inductions of LTD. J Neurosci. 5:7707
  PMID: 25573377
• Choi et al. (2015) PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome. Proc Natl Acad Sci U S A. 35:396
  PMID: 25568131
• Schmidt et al. (2015) Group I metabotropic glutamate receptor-mediated activation of PKC gamma in the nucleus accumbens core promotes the reinstatement of cocaine seeking. Addict Biol. 20:285
  PMID: 24506432
• Takano et al. (2014) Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices. Glia. 62:78
  PMID: 24272704
• Lee et al. (2014) Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase. Philos Trans R Soc Lond B Biol Sci. 369:20130158
  PMID: 24298159
• Chen and Shen (2013) Modulation of mGluR-dependent MAP1B translation and AMPA receptor endocytosis by microRNA miR-146a-5p. J Neurosci. 33:9013
  PMID: 23699512
• Iliff et al. (2013) Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice. Hum Mol Genet. 22:1180
  PMID: 23250915
• Xu et al. (2013) Simultaneous monitoring of presynaptic transmitter release and postsynaptic receptor trafficking reveals an enhancement of presynaptic activity in metabotropic glutamate receptor-mediated long-term depression. J Neurosci. 33:5867
  PMID: 23536098
• Sakuragi et al. (2013) Involvement of TrkB- and p75(NTR)-signaling pathways in two contrasting forms of long-lasting synaptic plasticity. J Vis Exp. 3:3185
  PMID: 24212565
• Sherkhane and Kapfhammer (2013) The plasma membrane Ca2+-ATPase2 (PMCA2) is involved in the regulation of Purkinje cell dendritic growth in cerebellar organotypic slice cultures. J Neurosci. 2013:321685
  PMID: 24288624
• Pasquale and Sherman (2013) A modulatory effect of the feedback from higher visual areas to V1 in the mouse. J Neurophysiol. 109:2618
  PMID: 23446698
• Oh et al. (2013) Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening. Proc Natl Acad Sci U S A. 110:E305
  PMID: 23269840
• Ramiro-Cortés (2013) Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression. PLoS One. 8:e71155
  PMID: 23951097
• Rojas et al. (2013) Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 83:106
  PMID: 23066089
• Crock et al. (2012) Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain. Eur J Neurosci. 32:14217
  PMID: 23055491
• Zhong et al. (2012) MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5. Stem Cell Reports. 32:12841
  PMID: 22973007
• Kapfhammer and Gugger (2012) The analysis of purkinje cell dendritic morphology in organotypic slice cultures. J Neurosci. NULL
  PMID: 22473312
• Hays et al. (2011) Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry. J Neurosci. 31:14223
  PMID: 21976507
• Coulon et al. (2011) Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling. Front Cell Neurosci. 4:132
  PMID: 21267426
• Bateup et al. (2011) Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function. Neurosci Lett. 31:8862
  PMID: 21677170
• Thompson and Perkel (2011) Endocannabinoids mediate synaptic plasticity at glutamatergic synapses on spiny neurons within a basal ganglia nucleus necessary for song learning. J Neurophysiol. 105:1159
  PMID: 21177997
• Kim et al. (2010) Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(β)42 from isolated intact nerve terminals. J Neurosci. 30:3870
  PMID: 20237257
• Schapitz et al. (2010) Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci. 30:12733
  PMID: 20861378
• Kolber et al. (2010) Activation of metabotropic glutamate receptor 5 in the amygdala modulates pain-like behavior. Sci Rep. 30:8203
  PMID: 20554871
• Hoffman et al. (2010) Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors. J Neurosci. 30:545
  PMID: 20071517
• Citri et al. (2010) Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. J Neurosci. 30:16437
  PMID: 21147983
• Glitsch (2010) Activation of native TRPC3 cation channels by phospholipase D. FASEB J. 24:318
  PMID: 19741172
• Citri et al. (2009) N-MthD.-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system. J Neurosci. 30:1443
  PMID: 19821836
• Wang et al. (2009) Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription. J Neurosci. 460:36
  PMID: 19446601
• Bagayogo and Dreyfus (2009) Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway. ASN Neuro. 1
  PMID: 19570026
• Patel et al. (2009) Mobilization of calcium from intracellular stores facilitates somatodendritic DA release. J Neurosci. 29:6568
  PMID: 19458227
• Zhang et al. (2008) The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. J Neurosci. 28:10561
  PMID: 18923032
• Marchaland et al. (2008) Fast subplasma membrane Ca²⁺ transients control exo-endocytosis of synaptic-like microvesicles in astrocytes. J Neurosci. 28:9122
  PMID: 18784293
• Kim et al. (2008) Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome. J Neurosci. 105:4429
  PMID: 18332424
• Grueter et al. (2008) In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression. J Neurosci. 28:9261
  PMID: 18784306
• Chiu and Castillo (2008) Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus. Neuropharmacology. 54:68
  PMID: 17706254
• Dai et al. (2008) A crucial role for cAMP and protein kinase A in D1 DA receptor regulated intracellular calcium transients. Neurosignals. 16:112
  PMID: 18253052
• McElligott (2008) Alpha1-adrenergic receptor-induced heterosynaptic long-term depression in the bed nucleus of the stria terminalis is disrupted in mouse models of affective disorders. Neuropsychopharmacology. 33:2313
  PMID: 18046308
• Muddashetty et al. (2007) Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J Neurosci. 27:5338
  PMID: 17507556
• Jan and Westbrook (2007) Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb. J Neurosci. 27:132
  PMID: 17202480
• Ziskin et al. (2007) Vesicular release of glutamate from unmyelinated axons in white matter. Proc Natl Acad Sci U S A. 10:321
  PMID: 17293857
• Brager and Johnston (2007) Plasticity of intrinsic excitability during long-term depression is mediated through mGluR-dependent changes in I(h) in hippocampal CA1 pyramidal neurons. J Neurosci. 27:13926
  PMID: 18094230
• Li et al. (2007) The different roles of cyclinD1-CDK4 in STP and mGluR-LTD during the postnatal development in mice hippocampus area CA1. BMC Dev Biol. 7:57
  PMID: 17535444
• Keuren-Jensen and Cline (2006) Visual experience regulates metabotropic glutamate receptor-mediated plasticity of AMPA receptor synaptic transmission by homer1a induction. J Neurosci. 26:7575
  PMID: 16855085
• Etkin et al. (2006) A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context. Neuron. 50:127
  PMID: 16600861
• Rancillac et al. (2006) Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum. J Neurosci. 26:6997
  PMID: 16807329
• Jiang et al. (2006) Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on DArgic neurons through a microtubule-dependent mechanism. J Neurosci. 26:4318
  PMID: 16624952
• Hsieh et al. (2006) AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron. 52:831
  PMID: 17145504
• Calò et al. (2005) Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci. 25:2245
  PMID: 15745950
• Gallagher et al. (2004) Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1. Neural Plast. 24:4859
  PMID: 15152046
• Nishi et al. (2003) Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling. J Neurosci. 100:1322
  PMID: 12538871
• Collard et al. (2002) Neutrophil-derived glutamate regulates vascular endothelial barrier function. J Biol Chem. 277:14801
  PMID: 11847215
• Huber et al. (2002) Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci U S A. 99:7746
  PMID: 12032354
• Job and Eberwine (2001) Identification of sites for exponential translation in living dendrites. Proc Natl Acad Sci U S A. 98:13037
  PMID: 11606784

There are no citations that match your criteria.

• mGluR antagonism with bath application

  Name: Anonymous
  Assay Type: In Vitro
  Cell Line/Tissue: Organotypic Hippocampus Slices
  Bath application on brain slice. Publication in progress.

• (RS)-3,5-DHPG application in brain slice preparation

  Name: Anonymous
  Assay Type: Ex Vivo
  (RS)-3,5-DHPG was bath applied and also pressure ejected at a concentration of up to 200 μM in a mouse brainstem slice preparation during whole-cell and perforated patch clamp. Results were consistent across different batch #s of (RS)-3,5-DHPG.
  (RS)-3,5-DHPG is light and air sensitive and is not stable in alkaline solutions. It is best to use aliquots within a week. Aliquots should not have a brown coloration under proper storage conditions.

There are no reviews that match your criteria.