RG 108

Tocris Bioscience, part of Bio-Techne | Catalog # 3295

Non-nucleoside DNA methyltransferase inhibitor
Catalog #
Availability
Size / Price
Qty
3295/10
3295/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Non-nucleoside DNA methyltransferase inhibitor

View all Methyltransferase Inhibitors »

Product Description

RG 108 is a non-nucleoside DNA methyltransferase inhibitor that blocks the enzyme active site. Inhibits DNA methylation in human cancer cell lines in vitro without detectable toxicity. Demethylates and reactivates epigenetically silenced tumor suppressor genes. Enhances the efficiency of induced pluripotent stem cell (iPS) generation.

Product Specifications

Molecular Weight

334.33

Formula

C19H14N2O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

N-Phthalyl-L-tryptophan

CAS Number

48208-26-0

PubChem ID

702558

InChI Key

HPTXLHAHLXOAKV-INIZCTEOSA-N

SMILES

O=C(C(C=CC=C4)=C4C3=O)N3[C@H](C(O)=O)CC2=CNC1=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.43 100
Ethanol 33.43 100

Preparing Stock Solutions for RG 108

The following data is based on the product molecular weight 334.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.99 mL 14.96 mL 29.91 mL
5 mM 0.60 mL 2.99 mL 5.98 mL
10 mM 0.30 mL 1.50 mL 2.99 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for RG 108

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RG 108

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.