Naltrexone hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0677
Non-selective opioid antagonist
Key Product Details
Description
Non-selective opioid antagonist
Product Description
Naltrexone hydrochloride is an opioid antagonist.Product Specifications
Molecular Weight
377.87
Formula
C20H23NO4.HCl
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydromorphinan-6-one hydrochloride
CAS Number
16676-29-2
PubChem ID
11957643
InChI Key
RHBRMCOKKKZVRY-ITLPAZOVSA-N
SMILES
Cl.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CCC2=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 37.79 | 100 |
Preparing Stock Solutions
for Naltrexone hydrochloride
The following data is based on the product molecular weight 377.87
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.65 mL | 13.23 mL | 26.46 mL |
| 5 mM | 0.53 mL | 2.65 mL | 5.29 mL |
| 10 mM | 0.26 mL | 1.32 mL | 2.65 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Tempel Supersensitivity of brain opiate receptor subtypes after chronic naltr. treatment. Life Sci. 1982 PMID: 6292636
- Zukin Naltrexone-induced opiate receptor supersensitivity. Brain Res. 1982 PMID: 6289965
- Gold Naltrexone, opiate addiction, and endorphins. Med.Res.Rev. 1982 PMID: 6289026
Product Specific Notices for Naltrexone hydrochloride
For research use only
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