Nalmefene hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 4085
Opioid receptor antagonist
Key Product Details
Description
Opioid receptor antagonist
Product Description
Nalmefene hydrochloride is an opioid receptor antagonist; displays a longer half life than Naloxone. Exhibits neuroprotective effects after traumatic brain injury in the rat.Product Specifications
Molecular Weight
375.89
Formula
C21H25NO3.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol hydrochloride
CAS Number
58895-64-0
PubChem ID
5388881
InChI Key
GYWMRGWFQPSQLK-OPHZJPRHSA-N
SMILES
C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(CC6CC6)CC4)[C@@](O)2CC3.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 37.59 | 100 | |
| DMSO | 37.59 | 100 |
Preparing Stock Solutions
for Nalmefene hydrochloride
The following data is based on the product molecular weight 375.89
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.66 mL | 13.30 mL | 26.60 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.32 mL |
| 10 mM | 0.27 mL | 1.33 mL | 2.66 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for Nalmefene hydrochloride
For research use only
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