Key Product Details
Description: | Non-selective opioid antagonist |
Chemical Name: | (5α)-4,5-Epoxy-3,14-dihydro-17-(2-propenyl)morphinan-6-one hydrochloride |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 363.84 |
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Citations for Naloxone hydrochloride (32)
Citations are publications that use Bio-Techne products. Selected citations for Naloxone hydrochloride include:
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Pedersen et al.
(2021)
A novel luminescence-based-β-arrestin recruitment assay for unmodified receptors.
J Biol Chem.
296:100503
PMID: 33684444 -
Hauser et al.
(2018)
Pharmacogenomics of GPCR Drug Targets.
Cell.
172:41
PMID: 29249361 -
Wang et al.
(2018)
Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits.
Neuron.
98:90
PMID: 29576387 -
Jeong et al.
(2018)
Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.
PLoS Biol.
16:e2004399
PMID: 29689050 -
Francois et al.
(2017)
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins.
Neuron.
93:822
PMID: 28162807 -
Liu et al.
(2015)
Morphological and physiological evidence of a synaptic connection between the lateral parabrachial nucleus and neurons in the A7 catecholamine cell group in rats.
J Biomed Sci.
22:79
PMID: 26385355 -
Gerhold et al.
(2015)
Pronociceptive and Antinociceptive Effects of Bupren. in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
J Neurosci.
35:9580
PMID: 26134641 -
Wang et al.
(2015)
Bupren.-elicited alteration of adenylate cyclase activity in human embryonic kidney 293 cells coexpressing κ-, μ-opioid and nociceptin receptors.
Nature.
19:2587
PMID: 26153065 -
Koch et al.
(2015)
Hypothalamic POMC neurons promote cannabinoid-induced feeding.
J Neurosci.
519:45
PMID: 25707796 -
Navratilova et al.
(2015)
Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain.
Front Endocrinol (Lausanne).
35:7264
PMID: 25948274 -
Levoye et al.
(2015)
A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate.
PLoS One.
6:167
PMID: 26617570 -
Chen et al.
(2015)
Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner.
Psychopharmacology (Berl).
10:e0145556
PMID: 26700862 -
Kelly et al.
(2015)
The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours.
World J Gastroenterol.
232:305
PMID: 24973897 -
Yi et al.
(2015)
Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions.
PLoS One.
22:49
PMID: 26150021 -
Pereira et al.
(2015)
Endogenous Opioid-Masked Latent Pain Sensitization: Studies from Mouse to Human.
Proc Natl Acad Sci U S A.
10:e0134441
PMID: 26305798 -
Chen et al.
(2014)
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
Neuropsychopharmacology.
20:1298
PMID: 24574803 -
Zhou et al.
(2013)
Development of functionally selective, small molecule agonists at kappa opioid receptors.
J Biol Chem.
288:36703
PMID: 24187130 -
Moser and Giesler
(2013)
Itch and analgesia resulting from intrathecal application of morphine: contrasting effects on different populations of trigeminothalamic tract neurons.
J Neurosci.
33:6093
PMID: 23554490 -
Romero-Picó et al.
(2013)
Hypothalamic κ-opioid receptor modulates the orexigenic effect of ghrelin.
J Biomed Sci.
38:1296
PMID: 23348063 -
Marti et al.
(2013)
Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.
Br J Pharmacol.
168:863
PMID: 22994368 -
Largent-Milnes et al.
(2013)
Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.
J Pharmacol Exp Ther.
347:7
PMID: 23860305 -
Navratilova et al.
(2012)
Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry.
FASEB J.
109:20709
PMID: 23184995 -
Ali
(2011)
CB1 modulation of temporally distinct synaptic facilitation among local circuit interneurons mediated by N-type calcium channels in CA1.
J Neurophysiol.
105:1051
PMID: 21123660 -
Largent-Milnes et al.
(2010)
Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.
Br J Pharmacol.
161:986
PMID: 20977451 -
Gross et al.
(2010)
Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts.
Am J Physiol Heart Circ Physiol.
298:H2201
PMID: 20400686 -
Cheng et al.
(2009)
Endogenous opiates in the nucleus tractus solitarius mediate electroacupuncture-induced sleep activities in rats.
Proc Natl Acad Sci U S A.
2011:159209
PMID: 19729491 -
Cruz et al.
(2008)
Absence and rescue of mor. withdrawal in GIRK/Kir3 knock-out mice.
J Neurosci.
28:4069
PMID: 18400906 -
García-Fuster et al.
(2007)
Effects of opiate drugs on Fas-associated protein with death domain (FADD) and effector caspases in the rat brain: regulation by the ERK1/2 MAP kinase pathway.
J Cell Mol Med.
32:399
PMID: 16482086 -
Patel et al.
(2007)
Mechanisms of cardiac protection from ischemia/reperfusion injury: a role for caveolae and caveolin-1.
Nat Commun.
21:1565
PMID: 17272740 -
Proudfoot et al.
(2006)
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain.
Curr Biol.
16:1591
PMID: 16920620 -
Melyan et al.
(2004)
Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors.
J Neurosci.
24:4530
PMID: 15140923 -
Moore et al.
(2003)
Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
Neuropsychopharmacology.
100:14397
PMID: 14608033
There are no citations that match your criteria.