Methylergometrine maleate

Name: Methylergometrine maleate
Brand: tocris
SKU: 0549

Catalog # 0549

Citations (2)

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	Active metabolite of methysergide (Cat. No. 1064)
Alternative Names:	Methylergonovine maleate
Chemical Name:	[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate
Purity:	≥98% (HPLC)
Molecular Weight:	455.51

View Full Technical Details for Methylergometrine maleate

Complete Your Research

Biological Activity

Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.

Technical Data

M. Wt	455.51
Formula	C₂₀H₂₅N₃O₂.C₄H₄O₄
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	57432-61-8
PubChem ID	5281072
InChi Key	NOFOWWRHEPHDCY-DAUURJMHSA-N
Smiles	OC(=O)\C=C/C(O)=O.[H][C@](CC)(CO)NC(=O)[C@@]1([H])CN(C)[C@]2([H])CC3=CNC4=C3C(=CC=C4)C2=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		25

Preparing Stock Solutions

The following data is based on the product molecular weight 455.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	8.78 mL	43.91 mL	87.81 mL
1.25 mM	1.76 mL	8.78 mL	17.56 mL
2.5 mM	0.88 mL	4.39 mL	8.78 mL
12.5 mM	0.18 mL	0.88 mL	1.76 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

MacLennan and Martin Actions of non-peptide ergot alkaloids at 5-HT₁-like and 5-HT₂ receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 2234096
Muller-Schweinitzer and Tapparelli Methylergometrine, an active metabolite of methysergide. Cephalalgia 1986 PMID: 3698092
Pertz 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 1993 PMID: 8133899
Merck Index

Citations (2)

Showing 1 - 2 of 2 citations Showing All

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Methylergometrine maleate include:

Chan et al. (2015) Ergot Alkaloids (Re)generate New Leads as Antiparasitics. Cell Signal. 9:e0004063
PMID: 26367744
Murray et al. (2011) Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 106:925
PMID: 21653728

There are no citations that match your criteria.

Showing 1 - 2 of 2 citations Showing All

Product Documents

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

Methylergometrine maleate

Order Information

Shipping Information

Key Product Details

Complete Your Research

Complete Your Experiment

Biological Activity

Technical Data

Solubility

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References

Citations (2)

Product Documents

COA

Certificate of Analysis

SDS

Bio-Techne Brands

Stay Connected