LY 379268 disodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 5064
Selective group II mGlu agonist; sodium salt of LY 379268 (Cat. No. 2453)
Key Product Details
Description
Selective group II mGlu agonist; sodium salt of LY 379268 (Cat. No. 2453)
Product Description
LY 379268 disodium salt is a sodium salt of LY 379268 (Cat. No. 2453), a highly selective group II mGlu receptor agonist.Product Specifications
Molecular Weight
231.11
Formula
C7H7NNa2O5
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid disodium salt
PubChem ID
10197984
InChI Key
YASVRZWVUGJELU-MDASVERJSA-N
SMILES
[H][C@]12[C@]([C@H]2[C@](O[Na])=O)([H])[C@@]([C@](O[Na])=O)(N)CO1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 23.11 | 100 |
Preparing Stock Solutions
for LY 379268 disodium salt
The following data is based on the product molecular weight 231.11
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.33 mL | 21.63 mL | 43.27 mL |
| 5 mM | 0.87 mL | 4.33 mL | 8.65 mL |
| 10 mM | 0.43 mL | 2.16 mL | 4.33 mL |
| 50 mM | 0.09 mL | 0.43 mL | 0.87 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bond Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanisms of action in vivo. J.Pharmacol.Exp.Ther. 2000 PMID: 10945827
- Collado (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 agonist with anxiolytic properties. J.Med.Chem. 2002 PMID: 12166935
- Bond LY379268, a potent and selective group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal cerebral ischaemia. Neurosci.Lett. 1999 PMID: 10515191
Product Specific Notices for LY 379268 disodium salt
For research use only
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