IDE 1

Tocris Bioscience, part of Bio-Techne | Catalog # 4015

Induces definitive endoderm formation in mouse and human ESCs
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Key Product Details

Description

Induces definitive endoderm formation in mouse and human ESCs

View all Compounds for Stem Cell Differentiation »

Product Description

IDE 1 is an induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 125 nM). Thought to activate the TGF-β signaling pathway; induces Smad2 phosphorylation and increases levels of Nodal expression.

This compound is mixture of E/Z isomers.

Licensing Information

Sold for research purpose under license from Harvard University.

Product Specifications

Molecular Weight

306.31

Formula

C15H18N2O5

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-[2-[(2-Carboxyphenyl)methylene]hydrazide]heptanoic acid

CAS Number

1160927-48-9

PubChem ID

66974738

InChI Key

ABKJCDILEUEJSH-UHFFFAOYSA-N

SMILES

OC(=O)CCCCCC(=O)NN=CC1=CC=CC=C1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
2eq. NaOH 30.63 100
DMSO 30.63 100

Preparing Stock Solutions for IDE 1

The following data is based on the product molecular weight 306.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.26 mL 16.32 mL 32.65 mL
5 mM 0.65 mL 3.26 mL 6.53 mL
10 mM 0.33 mL 1.63 mL 3.26 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for IDE 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IDE 1

For research use only

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