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Tocris Bioscience a Bio-Techne Brand

DNQX | CAS No. 2379-57-9 | Selective non-NMDA iGluR antagonist
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Key Product Details

Description: Selective non-NMDA iGluR antagonist
Chemical Name: 6,7-Dinitroquinoxaline-2,3-dione
Purity: ≥98% (HPLC)
Molecular Weight: 252.14

Citations for DNQX (110)

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  • Block of AMPAR sIPSCs
    Name: Anonymous
    Species: Human
    Assay Type: Ex Vivo
    Cell Line/Tissue: Stem cell - derived neurons
    DNQX was used to block spontaneous AMPA-receptor – generated excitatory post-synaptic currents (EPSCs) in stem-cell derived cultured dopamine neurons. 20 µM DNQX fully suppressed EPSC propagation, thus confirming the compound's specificity (see illustration). Preparation of 10 mM DMSO stock requires long sonication; in all other respects it is a perfect AMPA-receptor antagonist.
    DNQX Serum 0189

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Product Documents for DNQX

Certificate of Analysis

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