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AMPA Receptor Antagonists Small Molecule

Key Product Details

Description: Selective non-NMDA iGluR antagonist
Chemical Name: 6,7-Dinitroquinoxaline-2,3-dione
Purity: ≥98% (HPLC)

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Citations (110)

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  • Block of AMPAR sIPSCs
    Name: Anonymous | 15th Oct 2020
    Species: Human
    Assay Type: Ex Vivo
    Cell Line/Tissue: Stem cell - derived neurons
    DNQX was used to block spontaneous AMPA-receptor – generated excitatory post-synaptic currents (EPSCs) in stem-cell derived cultured dopamine neurons. 20 µM DNQX fully suppressed EPSC propagation, thus confirming the compound's specificity (see illustration). Preparation of 10 mM DMSO stock requires long sonication; in all other respects it is a perfect AMPA-receptor antagonist.
    Block of AMPAR sIPSCs Serum 0189

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