DCEBIO

Tocris Bioscience, part of Bio-Techne | Catalog # 1422

Activates Cl- conductance and hKCa3.1 channels
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Key Product Details

Description

Activates Cl- conductance and hKCa3.1 channels

View all CFTR Activators »

Product Description

DCEBIO is a stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. More potent than its analog 1-EBIO (Cat. No. 1041).

Product Specifications

Molecular Weight

231.08

Formula

C9H8Cl2N2O

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one

CAS Number

60563-36-2

PubChem ID

656765

InChI Key

LKHRMULASXZCLG-UHFFFAOYSA-N

SMILES

CCN1C(=O)NC2=C1C=C(Cl)C(Cl)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 23.11 100
Ethanol 23.11 100

Preparing Stock Solutions for DCEBIO

The following data is based on the product molecular weight 231.08

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.33 mL 21.64 mL 43.28 mL
5 mM 0.87 mL 4.33 mL 8.66 mL
10 mM 0.43 mL 2.16 mL 4.33 mL
50 mM 0.09 mL 0.43 mL 0.87 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for DCEBIO

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DCEBIO

For research use only

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