Cys-T7 Peptide

Name: Cys-T7 Peptide
Brand: Tocris Bioscience
SKU: 8904

Tocris Bioscience, part of Bio-Techne | Catalog # 8904

COA / SDS

Targeting peptide for the transferrin receptor (N-term Cys)

Key Product Details

Description:	Targeting peptide for the transferrin receptor (N-term Cys)
Purity:	≥95% (HPLC)
Molecular Weight:	996.15

View Full Technical Details for Cys-T7 Peptide

Technical Data
Citations

Biological Activity for Cys-T7 Peptide

Cys-T7 Peptide is a targeting peptide for the transferrin receptor (N-term Cys), a protein abundantly expressed on endothelial cells, including those forming the blood-brain barrier (BBB). Cys-T7 Peptide facilitates receptor-mediated endocytosis and transcytosis, making it an ideal targeting agent for drug delivery systems, such as lipid nanoparticles (LNPs), across biological barriers. N-term cys residue enables thiol-maleimide-based conjugation to DSPE-PEG 2000 Maleimide (Cat. No. 7947) commonly used to synthesize LNPs.

Technical Data for Cys-T7 Peptide

M. Wt	996.15
Formula	C₄₄H₆₅N₁₅O₁₀S
Single Letter Sequence	CHAIYPRH
Storage	Store at -20°C
Purity	≥95% (HPLC)
InChi Key	SMAWGRDHSYDHOY-WBLMYSKVSA-N
Smiles	O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CC=C(C=C2)O)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cys-T7 Peptide

Solubility

Soluble to 2mg/ml in water

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References for Cys-T7 Peptide

References are publications that support the biological activity of the product.

Han Peptide-functionalized lipid nanoparticles for targeted systemic mRNA delivery to the brain. Nano Lett. 2025 PMID: 39688915
Han Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 2011 PMID: 20971503