DSPE-PEG 2000 Maleimide
Tocris Bioscience, part of Bio-Techne | Catalog # 7947
PEGylated DSPE with a maleimide reactive group
Key Product Details
Description
PEGylated DSPE with a maleimide reactive group
Product Description
DSPE-PEG 2000 Maleimide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with a maleimide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used in antibody-targeted LNP-mRNA systems to generate transient antifibrotic chimeric antigen receptor (CAR) T cells in vivo.Product Specifications
Formula
(C2H4O)nC51H91N3O13P.NH4 or Na
Storage
Store at -20°C
Purity
≥90% (HPLC)
Chemical Name
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 10mg/ml in chloroform and to 10mg/ml in Ethanol with gentle warming |
Calculators
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Rurik CAR T cells produced in vivo to treat cardiac injury. Science 2022 PMID: 34990237
- Herrera-Barrera Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates. Sci.Adv. 2023 PMID: 36630502
- Ishida A combinatorial approach to producing sterically stabilized (Stealth) immunoliposomal drugs. FEBS Lett. 1999 PMID: 10571074
Product Specific Notices for DSPE-PEG 2000 Maleimide
For research use only
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