Key Product Details
Description: | Potent non-NMDA iGluR antagonist; more water soluble form of CNQX (Cat. No. 0190) |
Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione disodium |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 276.12 |
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Citations for CNQX disodium salt (36)
Citations are publications that use Bio-Techne products. Selected citations for CNQX disodium salt include:
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Evans et al.
(2020)
Functional Dissection of Basal Ganglia Inhibitory Inputs onto Substantia Nigra Dopaminergic Neurons.
Cell Rep.
32
PMID: 32937133 -
Pati et al.
(2020)
Chronic postnatal chemogenetic activation of forebrain excitatory neurons evokes persistent changes in mood behavior
Elife.
9
PMID: 32955432 -
He et al.
(2020)
Nucleus Accumbens Tac1-Expressing Neurons Mediate Stress-Induced Anhedonia-like Behavior in Mice.
Cell Rep.
33
PMID: 33147466 -
Green and Thayer et al.
(2019)
HIV gp120 upregulates tonic inhibition through α5-containing GABAARs.
Neuropharmacology.
149:161
PMID: 30797029 -
Spoljaric et al.
(2019)
KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice.
Cell Rep.
26:1073
PMID: 30699338 -
Gutzmann et al.
(2019)
Functional Coupling of Cav2.3 and BK Potassium Channels Regulates Action Potential Repolarization and Short-Term Plasticity in the Mouse Hippocampus.
Front Cell Neurosci.
13:27
PMID: 30846929 -
Styr et al.
(2019)
Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.
Neuron.
102:1009
PMID: 31047779 -
Kiritoshi and Neugebauer
(2018)
Pathway-specific alterations of cortico-amygdala transmission in an arthritis pain model.
ACS Chem Neurosci.
9:2252
PMID: 29630339 -
Riquelme et al.
(2018)
Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3.
Front Cell Neurosci.
12:12
PMID: 29440991 -
Grillo et al.
(2018)
A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration.
Neuron.
99:275
PMID: 29983327 -
Leroy et al.
(2018)
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.
Nature.
564:213
PMID: 30518859 -
Jalalvand et al.
(2018)
Cerebrospinal Fluid-Contacting Neurons Sense pH Changes and Motion in the Hypothalamus.
J Neurosci.
38:7713
PMID: 30037834 -
Yuan et al.
(2018)
A role for proteolytic regulation of δ-catenin in remodeling a subpopulation of dendritic spines in the rodent brain.
J Biol Chem.
293:11625
PMID: 29875160 -
Doshina et al.
(2017)
Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission.
Sci Rep.
7:370
PMID: 28337033 -
Athilingam et al.
(2017)
Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons.
Elife.
6
PMID: 29206101 -
Chaffiol et al.
(2017)
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.
Mol Ther.
25:2546
PMID: 28807567 -
Sternfeld et al.
(2017)
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells.
Elife.
6
PMID: 28195039 -
Medrihan et al.
(2017)
Initiation of Behavioral Response to Antidepressants by Cholecystokinin Neurons of the Dentate Gyrus.
Neuron.
95:564
PMID: 28735749 -
Maschi and Klyachko
(2017)
Spatiotemporal Regulation of Synaptic Vesicle Fusion Sites in Central Synapses.
Neuron.
94:65
PMID: 28343869 -
Paul et al.
(2017)
Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.
Cell.
171:522
PMID: 28942923 -
Edwards et al.
(2017)
Comparison of NMDA and AMPA Channel Expression and Function between Embryonic and Adult Neurons Utilizing Microelectrode Array Systems.
ACS Biomater Sci Eng.
3:3525
PMID: 29250595 -
Philippart et al.
(2016)
Differential Somatic Ca2+ Channel Profile in Midbrain DArgic Neurons
The Journal of Neuroscience.
6:7234
PMID: 27383597 -
Piet et al.
(2016)
Vasoactive Intestinal Peptide Excites GnRH Neurons in Male and Female Mice.
Endocrinology..
157:3621
PMID: 27501185 -
Cazares et al.
(2016)
Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn.
J Neurosci.
36:11208
PMID: 27807164 -
Li et al.
(2016)
A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors.
Cell.
167:60
PMID: 27641503 -
Mauger et al.
(2016)
Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.
Neuron.
92:1266
PMID: 28009274 -
Baltz and Voigt
(2015)
Interaction of electrically evoked activity with intrinsic dynamics of cultured cortical networks with and without functional fast GABAergic synaptic transmission.
Front Cell Neurosci.
9:272
PMID: 26236196 -
Schitine et al.
(2015)
Functional plasticity of GAT-3 in avian Müller cells is regulated by neurons via a glutamatergic input.
J Neurosci.
82:42
PMID: 25700791 -
Zhao et al.
(2015)
Extracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampus.
Neuropsychopharmacology.
35:308
PMID: 25568123 -
Einarsson et al.
(2015)
Systems reconsolidation reveals a selective role for the anterior cingulate cortex in generalized contextual fear memory expression.
J Endocrinol.
40:480
PMID: 25091528 -
Schubert et al.
(2014)
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis.
Acta Neuropathol.
128:835
PMID: 25341622 -
Villers et al.
(2014)
Long-term potentiation can be induced in the CA1 region of hippocampus in the absence of αCaMKII T286-autophosphorylation.
Learn Mem.
21:616
PMID: 25322797 -
Guo et al.
(2012)
Tissue engineering the monosynaptic circuit of the stretch reflex arc with co-culture of embryonic motoneurons and proprioceptive sensory neurons.
Biomaterials.
33:5723
PMID: 22594977 -
Janssen et al.
(2012)
Neuregulin directly decreases voltage-gated sodium current in hippocampal ErbB4-expressing interneurons.
J Neurosci.
32:13889
PMID: 23035098 -
Carlson et al.
(2012)
Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica.
Brain Behav.
2:391
PMID: 22950043 -
Yuan et al.
(2009)
The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-MthD.-aspartate receptors.
J Biol Chem.
284:12862
PMID: 19240037
There are no citations that match your criteria.
Customer Reviews for CNQX disodium salt (3)
Customer Images
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Species: MouseAssay Type: In Vivo30uM CNQX
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Species: MouseAssay Type: Ex VivoAMPA antagonist used in whole cell recordings. We made a stock solution at 20mM in water and dilute to 10uM for experiments. EPSCs are wiped out, so this concentration appears effective despite concerns over uniformity.The stock solution does not look uniform, so we stir it well before diluting to final concentration. In the picture you can see how the drug is coming out of solution (powder on the walls of the vial).
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Species: RatAssay Type: Ex VivoAMPA receptor antagonist used at 20uM in rat brain sliceStock solution is little sticky. Voltex well before making dilution.
There are no reviews that match your criteria.