Na+/2Cl-/K+ (NKCC) symporter inhibitor
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Key Product Details
Description: | Na+/2Cl-/K+ (NKCC) symporter inhibitor |
Chemical Name: | 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 364.42 |
Citations for Bumetanide (12)
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Citations are publications that use Bio-Techne products. Selected citations for Bumetanide include:
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Babola et al.
(2020)
Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space.
Elife.
9:e52160
PMID: 31913121 -
Spoljaric et al.
(2019)
KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice.
Cell Rep.
26:1073
PMID: 30699338 -
Bhandage et al.
(2019)
Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling.
Front Cell Infect Microbiol.
9:73
PMID: 30949457 -
Alfonsa et al.
(2016)
Cl- out is a novel cooperative optogenetic tool for extruding chloride from neurons
Nature Communications.
7:13495
PMID: 27853135 -
Choe et al.
(2015)
High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons.
Mol Brain.
85:549
PMID: 25619659 -
Pál et al.
(2015)
Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity.
Neuron.
8:35
PMID: 26043770 -
Angelantonio et al.
(2014)
A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium.
Cell Death Dis.
5:e1501
PMID: 25356870 -
Deeb et al.
(2013)
Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of D.pam during hyperexcited states.
Eur J Neurosci.
38:2453
PMID: 23627375 -
Haam et al.
(2012)
GABA is excitatory in adult vasopressinergic neuroendocrine cells.
J Neurosci.
32:572
PMID: 22238092 -
Shulga et al.
(2012)
The loop diuretic bumet. blocks posttraumatic p75NTR upregulation and rescues injured neurons.
J Neurosci.
32:1757
PMID: 22302815 -
Shulga et al.
(2008)
Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons.
J Neurosci.
28:6996
PMID: 18596173 -
Safiulina et al.
(2008)
Low expression of Kv7/M channels facilitates intrinsic and network bursting in the developing rat hippocampus.
J Physiol.
586:5437
PMID: 18801845
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