Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Potent γ-secretase inhibitor|
|Chemical Name:||2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid|
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Citations for BMS 299897 (2)
Citations are publications that use Bio-Techne products. Selected citations for BMS 299897 include:
Liu et al.
APP upregulation contributes to retinal ganglion cell degeneration via JNK3.
Cell Death Differ.
Pitt et al.
Neuroprotective astrocyte-derived Ins/IGF-1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers.
Mol Biol Cell.
There are no citations that match your criteria.
Customer Reviews for BMS 299897 (2)
Species: RatAssay Type: In VitroCell Line/Tissue: Hippocampal neurongamma -secretase (100 nM BMS 299897 and 250 nM DAPT)
Species: HumanAssay Type: In VitroCell Line/Tissue: Hippocampal neuronUsing more specific inhibitors, we ruled out the involvement of gamma -secretase (100 nM BMS 299897 and 250 nM DAPT) or matrix metalloproteinases 1, 2, 3, 7, 9, 14, and 17 (0.1–1 μM batimastat and marimastat), as their inhibitors failed to alter A beta O release
There are no reviews that match your criteria.