BD 1047 dihydrobromide
Tocris Bioscience, part of Bio-Techne | Catalog # 0956
σ1 selective antagonist
Product Description
BD 1047 dihydrobromide is a σ1 receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ1 and σ2 sites.Product Specifications
Molecular Weight
437.04
Formula
C13H20Cl2N2.2HBr
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
Chemical Name
N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide
CAS Number
138356-21-5
PubChem ID
45073418
InChI Key
WOALTFHGLDVJHK-UHFFFAOYSA-N
SMILES
Br.Br.CN(C)CCN(C)CCC1=CC=C(Cl)C(Cl)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 21.85 | 50 | |
| DMSO | 21.85 | 50 |
Preparing Stock Solutions
for BD 1047 dihydrobromide
The following data is based on the product molecular weight 437.04
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.58 mL | 22.88 mL | 45.76 mL |
| 2.5 mM | 0.92 mL | 4.58 mL | 9.15 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
| 25 mM | 0.09 mL | 0.46 mL | 0.92 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Matsumoto Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol. 1995 PMID: 8566098
- Romieu Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 2000 PMID: 11006959
- Garrone Effects of traz. on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol. 2000 PMID: 10913582
Product Specific Notices for BD 1047 dihydrobromide
For research use only
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