BD 1047 dihydrobromide

Name: BD 1047 dihydrobromide
Brand: Tocris Bioscience
SKU: 0956
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0956

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Citations (19)

COA / SDS

σ1 selective antagonist

Key Product Details

Description:	σ₁ selective antagonist
Chemical Name:	N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide
Purity:	≥99% (HPLC)
Molecular Weight:	437.04

View Full Technical Details for BD 1047 dihydrobromide

Technical Data
Citations / Reviews (1)

Biological Activity for BD 1047 dihydrobromide

BD 1047 dihydrobromide is a σ₁ receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (Cat. No. 0883) but with higher affinity (approximately 10-fold) at both σ₁ and σ₂ sites.

Technical Data for BD 1047 dihydrobromide

M. Wt	437.04
Formula	C₁₃H₂₀Cl₂N₂.2HBr
Storage	Desiccate at +4°C
Purity	≥99% (HPLC)
CAS Number	138356-21-5
PubChem ID	45073418
InChi Key	WOALTFHGLDVJHK-UHFFFAOYSA-N
Smiles	Br.Br.CN(C)CCN(C)CCC1=CC=C(Cl)C(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for BD 1047 dihydrobromide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	21.85	50
	DMSO	21.85	50

Preparing Stock Solutions for BD 1047 dihydrobromide

The following data is based on the product molecular weight 437.04.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.58 mL	22.88 mL	45.76 mL
2.5 mM	0.92 mL	4.58 mL	9.15 mL
5 mM	0.46 mL	2.29 mL	4.58 mL
25 mM	0.09 mL	0.46 mL	0.92 mL

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Reconstitution Calculator

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References for BD 1047 dihydrobromide

References are publications that support the biological activity of the product.

Matsumoto Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol. 1995 PMID: 8566098
Romieu Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 2000 PMID: 11006959
Garrone Effects of traz. on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol. 2000 PMID: 10913582