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BD 1063 dihydrochloride

Sigma1 Receptor Ligands Small Molecule
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Key Product Details

Description: Selective σ1 ligand, putative antagonist
Chemical Name: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride
Purity: ≥99% (HPLC)
Molecular Weight: 346.13

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  • BD1063 binds to sigma-1 receptor
    Name: Timur Mavlyutov
    Species: Mouse
    Assay Type: In Vitro
    We used BD1063 compound as a sigma-1 receptor protector against photolabeling by radioactive iodoazidofenpropimorph in mouse spinal cord homogenate and saw good protective effect with concentration of 10uM.
  • Use of BD 1063 in mouse brain slices
    Name: Jordan Yorgason
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: C57
    We used BD 1063 as a selective sigma antagonist to test if methamphetamine effects on dopamine release involved sigma receptor activation. BD 1063 (100nM) was applied before methamphetamine treatment. Drug was easy to use, and Tocris' recommendation on concentration for selectivity was useful for the study.
    BD 1063 dihydrochloride Serum 0883

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