3-Bromo-7-nitroindazole
Tocris Bioscience, part of Bio-Techne | Catalog # 0735
Selective nNOS inhibitor
Product Description
3-Bromo-7-nitroindazole is a potent inhibitor of rat cerebellar nitric oxide synthase; more potent than 7-nitroindazole (Cat. No. 0602).Product Specifications
Molecular Weight
242.03
Formula
C7H4BrN3O2
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
CAS Number
74209-34-0
PubChem ID
1649
InChI Key
NFSTZPMYAZRZPC-UHFFFAOYSA-N
SMILES
[O-][N+](=O)C1=C2NN=C(Br)C2=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.2 | 100 | |
| Ethanol | 12.1 | 50 |
Preparing Stock Solutions
for 3-Bromo-7-nitroindazole
The following data is based on the product molecular weight 242.03
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.13 mL | 20.66 mL | 41.32 mL |
| 5 mM | 0.83 mL | 4.13 mL | 8.26 mL |
| 10 mM | 0.41 mL | 2.07 mL | 4.13 mL |
| 50 mM | 0.08 mL | 0.41 mL | 0.83 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bland-Ward Isoform selectivity of indazole-based nitric oxide synthase inhibitors. Br.J.Pharmacol.
- Bland-Ward and Moore 7-Nitroindazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci. 1995 PMID: 7544863
Product Specific Notices for 3-Bromo-7-nitroindazole
For research use only
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