LY 341495 disodium salt
Tocris Bioscience, part of Bio-Techne | Catalog # 4062
Potent and selective group II mGlu antagonist; disodium salt of LY 341495 (Cat. No. 1209)
Key Product Details
Description
Potent and selective group II mGlu antagonist; disodium salt of LY 341495 (Cat. No. 1209)
Product Description
LY 341495 disodium salt is a Highly potent and selective group II metabotropic glutamate receptor antagonist. Disodium salt of LY 341495 (Cat. No. 1209).Product Specifications
Molecular Weight
397.33
Formula
C20H17NNa2O5
Storage
Store at -20°C
Purity
≥97% (HPLC)
Chemical Name
(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid disodium salt
PubChem ID
90488907
InChI Key
UYFREPWOVKMBOV-AUZVYACCSA-L
SMILES
[Na+].[Na+].[H][C@@]1(C[C@@H]1C([O-])=O)[C@@](N)(CC1C2=CC=CC=C2OC2=C1C=CC=C2)C([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 39.73 | 100 |
Preparing Stock Solutions
for LY 341495 disodium salt
The following data is based on the product molecular weight 397.33
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.52 mL | 12.58 mL | 25.17 mL |
| 5 mM | 0.50 mL | 2.52 mL | 5.03 mL |
| 10 mM | 0.25 mL | 1.26 mL | 2.52 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.50 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ornstein 2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl) glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioav J.Med.Chem. 1998 PMID: 9464367
- Johnson [3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. Neuropharmacology 1999 PMID: 10530814
- Fitzjohn The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacology 1998 PMID: 9886667
Product Specific Notices for LY 341495 disodium salt
For research use only
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