Recombinant R. sanguineus Evasin-1 Fc Chimera Protein, CF
R&D Systems, part of Bio-Techne | Catalog # 10016-EV
Key Product Details
Source
HEK293
Accession #
Structure / Form
Disulfide-linked homodimer
Conjugate
Unconjugated
Applications
Bioactivity
Product Specifications
Source
Human embryonic kidney cell, HEK293-derived r. sanguineus Evasin-1 protein
Human IgG1 (Met-Asp-Pro100 - Lys330) |
IEGR | R. sanguineus Evasin-1 (Glu21-Asn114) Accession # P0C8E7.1 |
N-terminus | C-terminus |
Purity
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal Sequence Analysis
Met-Asp-Pro100
Predicted Molecular Mass
37 kDa
SDS-PAGE
40-61 kDa, reducing conditions
Activity
Measured by its ability to inhibit CCL3/MIP-1 alpha-induced chemotaxis of BaF3 mouse pro-B cells transfected with human CCR5.
The ED50 for this effect is 0.2-1.2 μg/mL
The ED50 for this effect is 0.2-1.2 μg/mL
Scientific Data Images for Recombinant R. sanguineus Evasin-1 Fc Chimera Protein, CF
Recombinant R. sanguineus Evasin-1 Fc Chimera Protein Binding Activity
Recombinant R. sanguineus Evasin-1 Fc Chimera (Catalog # 10016-EV) inhibits Recombinant Human CCL-3/MIP-1 alpha-induced chemotaxis of BaF3 mouse pro B cells transfected with human CCR5. The ED50 for this effect is 0.2-1.2 μg/mL.Formulation, Preparation and Storage
10016-EV
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 500 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: Evasin-1
References
- Frauenschuh, A. et al. (2007) J. Biol. Chem. 282:27250.
- Deruaz, M. et al. (2008) J. Exp. Med. 205:2019.
- Deruaz, M. et al. (2013) FEBS J. 280:4876.
Long Name
Evasin-1
UniProt
Additional Evasin-1 Products
Product Documents for Recombinant R. sanguineus Evasin-1 Fc Chimera Protein, CF
Product Specific Notices for Recombinant R. sanguineus Evasin-1 Fc Chimera Protein, CF
For research use only
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