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Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed) Best Seller

Catalog # 6449-TEC | R&D Systems, Inc. a Bio-Techne Brand
(2)
Graph showing dose-dependent bioactivity of Human TRANCE protein
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6449-TEC-010/CF

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6449-TEC-010
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Setting the standard in quality research reagents

Key Product Details

Source: E. coli
Accession #: AAC51762
Applications: Bioactivity

Citations for Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed) (3)

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FAQs for Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed)

  • What are the differences between the Recombinant Human TRANCE/RANK L/TNFSF11 Protein (Catalog # 390-TN) and the Recombinant Human TRANCE/RANK L/TNFSF11 (Catalog # 6449-TEC)?

    6449-TEC is the truncated version of 390-TN, and it contains a 10-His tag in the N-terminus. The bioactivity of 390-TN and 6449-TEC are measured in the same assay described in the datasheet, "Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells." However, 390-TN utilizes a cross-linking antibody, MAB050, as it requires receptor trimerization which results in higher bioactivity. The ED50 for 390-TN is 1.5-7.5 ng/mL in the presence of MAB050, while the ED50 for 6449-TEC is 2-12 ng/mL.

Product Documents for Recombinant Human TRANCE/RANK L/TNFSF11 (E. coli-expressed)

Certificate of Analysis

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