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Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF

R&D Systems, Inc. a Bio-Techne Brand

Graph showing bioactivity of Human PD-L1 protein (B7-H1 protein)
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156-B7-100
156-B7-01M
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Key Product Details

Source: NS0
Accession #: Q9NZQ7
Structure / Form: Disulfide-linked homodimer
Applications: Bioactivity

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Citations for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (23)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF include:

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Customer Reviews for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (21)

4.9 out of 5
21 customer ratings
5 stars
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  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Reason for Rating: Tested binding of PDL1-Fc w/ PD-1 using Octet. KD ~1.5uM
    Verified Customer | Posted 06/19/2020
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF Binding assay/Protein-protein interaction 156-B7
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Sarah Garrett
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 11/15/2019
    HEK cells expressing mCherry alone (LEFT) or hPD-1 mCherry (RIGHT) were incubated with 0.25 ug of hPD-L1 hIgG1. Binding was monitored by flow cytometry using an anti-human 488 secondary antibody.
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF Binding assay/Protein-protein interaction 156-B7
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Jenna Nguyen
    Application: Stem/Immune cell maintenance or differentiation
    Verified Customer | Posted 12/06/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Jenna Nguyen
    Application: Cell Adhesion
    Verified Customer | Posted 10/24/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Jenna Nguyen
    Application: Enzymatic activity in vitro
    Verified Customer | Posted 10/12/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Jenna Nguyen
    Application: CellProlif
    Verified Customer | Posted 09/28/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 08/26/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: SDS-PAGE Control
    Verified Customer | Posted 04/12/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 03/30/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: SDS-PAGE Control
    Verified Customer | Posted 03/15/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: SDS-PAGE Control
    Verified Customer | Posted 03/11/2018
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Reason for Rating: Binding observed.
    Verified Customer | Posted 02/07/2018
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF Binding assay/Protein-protein interaction 156-B7
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Amit Kumar
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 12/18/2017
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 12/06/2017
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Konrad Gabrusiewicz
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 12/01/2017
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 11/27/2017
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF Binding assay/Protein-protein interaction 156-B7
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 11/18/2017
  • Name: Jenna Nguyen
    Application: Binding assay/Protein-protein interaction
    Verified Customer | Posted 07/20/2017
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: Cell Adhesion
    Verified Customer | Posted 07/20/2017
  • Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF
    Name: Anonymous
    Application: SPR assay for Kinetics between PDL-1 and AntiPDL-1 Antibody
    Verified Customer | Posted 07/14/2017
    SPR experiment
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF Other 156-B7
  • Name: Anonymous
    Verified Customer | Posted 05/23/2017
    Using Octet, we tested the ability of B7-H1/PD-L1 to bind recombinant PD-1 (R&D 8986-PD-100) and found them to specifically bind to each other.
    Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF 156-B7

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FAQs for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF

  • What is the pI (Isoelectric Point) of Recombinant Human PD-L1/B7-H1 Fc Chimera Protein (Catalog # 156-B7)?

    The calculated pI for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein (Catalog # 156-B7) is 7.1.

  • Do you have a human IgG1 Fc region that would be a suitable negative control for the linker sequence and Fc region in Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (Catalog # 156-B7)?

    Yes, we offer Recombinant Human IgG1 Fc Protein, CF (Catalog # 110-HG), which contains the human IgG Fc region and linker sequence.

  • Has Recombinant Human PD-L1/B7-H1 Fc Chimera Protein (Catalog # 156-B7), been evaluated on primary cells?

    Bioactivity of Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (Catalog # 156-B7) is evaluated by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocyte primary cells. The ED50 for this effect is 0.075-0.75 μg/mL. We recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

  • What are the differences between Recombinant Human PD-L1/B7-H1 His-tag Protein, CF (Catalog # 9049-B7) and Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (Catalog # 156-B7)?

    Recombinant Human PD-L1/B7-H1 Protein, CF (Catalog # 9049-B7) consists of (Phe19-Thr239) from Accession # Q9NZQ7. It has a His tag but no Fc chimera. Activity for 9049-B7 is measured in a binding assay with Recombinant Human PD‑1 Fc Chimera (Catalog # 1086-PD). Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF (Catalog 156-B7) consists of the same region (Phe19-Thr239), but instead of a His tag, it has a linker region and an Fc chimera. Activity for 156-B7 is assessed in a cell-based assay measuring IL-2 production by human T lymphocytes.

Product Documents for Recombinant Human PD-L1/B7-H1 Fc Chimera Protein, CF

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