Recombinant Human MUC-1 Fc Chimera Protein, CF
Catalog # 10332-MU | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Accession #
Source
Structure / Form
Conjugate
Applications
Product Specifications
Source
Human MUC-1 (Ser24-Ser380) Accession # P15941.3 |
IEGRMD | Human IgG1 (Pro100-Lys330) |
N-terminus | C-terminus |
Purity
Endotoxin Level
N-terminal Sequence Analysis
Predicted Molecular Mass
SDS-PAGE
Activity
When Recombinant Human MUC-1 Fc Chimera (Catalog # 10332-MU) is immobilized at 1 µg/mL (100 µL/well), Recombinant Human Siglec‑9 Fc Chimera (Catalog # 1139-SL) binds with an ED50 of 0.2-1.4 μg/mL.
Scientific Data Images for Recombinant Human MUC-1 Fc Chimera Protein, CF
Recombinant Human MUC-1 Fc Chimera Protein Binding Activity
When Recombinant Human MUC-1 Fc Chimera (Catalog # 10332-MU) is immobilized at 1 µg/mL (100 µL/well), Recombinant Human Siglec-9 Fc Chimera (Catalog # 1139-SL) binds with an ED50 of 0.2-1.4 µg/mL.Recombinant Human MUC-1 Fc Chimera Protein SDS-PAGE
2 μg/lane of Recombinant Human MUC-1 Fc Chimera (Catalog # 10332-MU) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 157-192 kDa and 310-380 kDa, respectively.Formulation, Preparation and Storage
10332-MU
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 400 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: MUC-1
References
- Rughetti, A. et al. (2005) J. Immunol. 174:7764.
- Engelstaedter, V. et al. (2012) BMC Cancer 12:600.
- Taylor-Papadimitriou, J. et al. (1999) Biochim. Biophys. Acta 1455:301.
- Geng, Y. et al. (2012) Front Oncol. 2:76.
- Tanida, S. et al. (2013) J Biol Chem. 288:31842.
- Beatson, R. et al. (2016) Nat Immunol. 17:1273.
- Piyush, T. et al. (2017) Cell Death Differ. 24:1937.
Long Name
Alternate Names
Entrez Gene IDs
Gene Symbol
UniProt
Product Documents for Recombinant Human MUC-1 Fc Chimera Protein, CF
Product Specific Notices for Recombinant Human MUC-1 Fc Chimera Protein, CF
For research use only
Citations for Recombinant Human MUC-1 Fc Chimera Protein, CF (1)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human MUC-1 Fc Chimera Protein, CF include:
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Species: Human
Sample Types: Recombinant Protein
Applications: BioassayK Pedram et al. (2022-09-19), Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals Proceedings of the National Academy of Sciences of the United States of America, 2022-0119(39):e2117105119.
PMID: 36122205
There are no citations that match your criteria.
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