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Recombinant Human/Mouse/Rat BMP-2 Protein

Catalog # 355-BM | R&D Systems, Inc. a Bio-Techne Brand
Graph showing dose-dependent bioactivity of Human BMP-2 protein
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Setting the standard in quality research reagents

Key Product Details

Source: CHO
Accession #: P12643
Structure / Form: Disulfide-linked homodimer
Applications: Bioactivity

Citations for Recombinant Human/Mouse/Rat BMP-2 Protein (185)

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Customer Reviews for Recombinant Human/Mouse/Rat BMP-2 Protein (11)

4.8 out of 5
11 customer ratings
5 stars
82%
4 stars
18%
3 stars
0%
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  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Application: Enzymatic activity in vitro
    Reason for Rating: 50 ng/ml works well to induce osteoblast differentiation.
    Verified Customer | Posted 04/05/2022
    Recombinant Human/Mouse/Rat BMP-2 Protein Enzymatic activity in vitro 355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: zeji du
    Application: Stem/Immune cell maintenance or differentiation
    Reason for Rating: I used it for osteoblasts differentiation, Arizarin staining.It keeps and promotes osteoblasts mineralization very well.
    Verified Customer | Posted 05/27/2021
    Recombinant Human/Mouse/Rat BMP-2 Protein Stem/Immune cell maintenance or differentiation  355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Application: In vitro bioactivity in cell culture
    Reason for Rating: I used BMP2 to activate BMP reporter and it worked very well.
    Verified Customer | Posted 09/15/2020
    Recombinant Human/Mouse/Rat BMP-2 Protein In vitro bioactivity in cell culture 355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Application: CellProlif
    Reason for Rating: Another great product made by R&D Systems. Always produces consistent and reliable results. Great as a control.
    Verified Customer | Posted 10/09/2019
    Recombinant Human/Mouse/Rat BMP-2 Protein Cell Proliferation 355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Application: Immunofluorescence
    Verified Customer | Posted 10/26/2018
    Recombinant Human/Mouse/Rat BMP-2 Protein Other 355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Cody Saylor
    Application: In vitro bioactivity in cell culture
    Reason for Rating: Performed as expected to force differentiation of C2C12's to Osteoblasts
    Verified Customer | Posted 09/07/2017
  • Name: Abby Sukarto
    Verified Customer | Posted 05/03/2017
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Javier Aragón
    Application: BMP-2 Delivery System
    Verified Customer | Posted 01/05/2017
    Recombinant Human/Mouse/Rat BMP-2 Protein Other 355-BM
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Application: Binding assay/Protein-protein interaction
    Reason for Rating: Materials performed as expected.
    Verified Customer | Posted 05/13/2016
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Frank Grosso
    Application: Binding assay/Protein-protein interaction
    Reason for Rating: This protein performed exactly as expected.
    Verified Customer | Posted 01/15/2016
  • Recombinant Human/Mouse/Rat BMP-2 Protein
    Name: Anonymous
    Sample Tested: C2C12 mouse myoblast cell line
    Verified Customer | Posted 10/26/2015
    ALP assay measuring osteogenic induction of C2C12 cells treated with BMP-2.
    Recombinant Human/Mouse/Rat BMP-2 Protein 355-BM

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FAQs for Recombinant Human/Mouse/Rat BMP-2 Protein

  • What is the difference between the two Recombinant Human/Mouse/Rat BMP-2 Proteins (Catalog # 355-BM and 355-BEC)?

    Catalog # 355-BM is produced in a mammalian system using CHO cells and exhibits better activity in our routine QC bioassay, while Catalog # 355-BEC is produced in an E. coli expression system and is less expensive. Bioactivity of both Human/Mouse/Rat BMP-2 Proteins is measured in an alkaline phosphatase assay using by ATDC5 mouse chondrogenic cells. For 355-BM, the ED50 for this effect is 40-200 ng/mL, while for 355-BEC, the ED50 range is 80-480 ng/mL. We recommend reviewing our list of publications under the Citations tab for both 355-BM and 355-BEC to determine which of the two proteins is most suitable for your experiment.

  • What is the sequence homology between human, mouse and rat BMP-2

    Mature human BMP-2 shares 100% aa sequence identity with mouse and rat BMP-2.

  • Does Recombinant Human/Mouse/Rat BMP-2 Protein (Catalog # 355-BM) have a histidine tag?

    Recombinant Human/Mouse/Rat BMP-2 Protein (Catalog # 355-BM) does not contain a histidine tag. The sequence of this protein contains Gln283-Arg396 aa based on Accession # P12643.

Product Documents for Recombinant Human/Mouse/Rat BMP-2 Protein

Certificate of Analysis

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