Recombinant Human/Mouse/Rat BMP-2 Protein
Catalog # 355-BM | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | CHO |
Accession #: | P12643 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
Citations for Recombinant Human/Mouse/Rat BMP-2 Protein (185)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human/Mouse/Rat BMP-2 Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayErdem et al. (2023-07-06), MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms Nature communications
PMID: 37414767 -
Species: Mouse
Sample Types: Whole Cells
Applications: Differentiation, DifferentiationNagasaki et al. (2023-05-25), Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2 FEBS open bio
PMID: 37226930 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayS Das et al. (2023-02-16), ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival The Journal of Biological Chemistry, 2023-00(0):103031.
PMID: 36805334 -
Species: Rat
Sample Types: Whole Tissue
Applications: In VivoY Hachinohe et al. (2023-01-06), Self-Prepared Hyaluronic Acid/Alkaline Gelatin Composite with Nano-Hydroxyapatite and Bone Morphogenetic Protein for Cranial Bone Formation International Journal of Molecular Sciences, 2023-024(2).
PMID: 36674618 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoY Hachinohe et al. (2022-12-08), Bone Formation on Murine Cranial Bone by Injectable Cross-Linked Hyaluronic Acid Containing Nano-Hydroxyapatite and Bone Morphogenetic Protein Polymers, 2022-114(24).
PMID: 36559734 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZ Shonibare et al. (2022-07-26), Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer Oncogene, 2022-040(4):111066.
PMID: 35905726 -
Species: Phallusia mammillata
Sample Types: Embryos
Applications: BioassayR Chowdhury et al. (2022-06-27), Highly distinct genetic programs for peripheral nervous system formation in chordates Bmc Biology, 2022-020(1):152.
PMID: 35761237 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Vora et al. (2022-05-31), Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans Cell bioscience, 2022-05-31;12(1):76.
PMID: 35641992 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAP Leinroth et al. (2022-05-10), Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations Cell Reports, 2022-039(6):110785.
PMID: 35545045 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureF Kawecki et al. (2022-03-18), Preclinical Evaluation of BMP-9-Treated Human Bone-like Substitutes for Alveolar Ridge Preservation following Tooth Extraction International Journal of Molecular Sciences, 2022-023(6).
PMID: 35328724 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureS Nagel et al. (2022-03-16), The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia International Journal of Molecular Sciences, 2022-023(6).
PMID: 35328612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayI López-Anto et al. (2022-03-09), Dynamic regulation of myofibroblast phenotype in cellular senescence Aging Cell, 2022-00(0):e13580.
PMID: 35266275 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPR Gajjala et al. (2021-10-22), Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis JCI Insight, 2021-10(0).
PMID: 34520400 -
Species: Rats
Sample Types: In Vivo
Applications: In VivoM Moncayo-Do et al. (2021-09-20), The Effect of Pore Directionality of Collagen Scaffolds on Cell Differentiation and In Vivo Osteogenesis Polymers, 2021-013(18).
PMID: 34578088 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Zheng et al. (2021-09-11), Bmp Signaling Regulates Hand1 in a Dose-Dependent Manner during Heart Development International Journal of Molecular Sciences, 2021-022(18).
PMID: 34576009 -
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA CapturePS Briquez et al. (2021-06-11), Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion Science Advances, 2021-07(24).
PMID: 34117071 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVC Cheung et al. (2021-05-18), Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua Cell Reports, 2021-035(7):109138.
PMID: 34010658 -
Species: Human, Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: BioassayC Zhou et al. (2021-02-13), FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex Journal of Cellular and Molecular Medicine, 2021-00(0).
PMID: 33580754 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Hiraoka et al. (2020-11-01), Bone Morphogenetic Proteins Inhibit Ciliogenesis of Ependymal Cells in Vitro Tohoku J Exp Med, 2020-1252(3):199-208.
PMID: 33087680 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBE Schwartz et al. (2020-10-07), Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings Cells, 2020-19(10).
PMID: 33036387 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Leiendecke et al. (2020-10-07), LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma EMBO Mol Med, 2020-10(0):e12525.
PMID: 33026191 -
Species: Human
Sample Types: Cell Culture Supernates, Recombinant Protein
Applications: Surface Plasmon ResonanceT Mang et al. (2020-08-21), BMPR1A is necessary for chondrogenesis and osteogenesis while BMPR1B prevents hypertrophic differentiation J. Cell. Sci., 2020-00(0).
PMID: 32764110 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassaySK Meurer et al. (2020-08-03), Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells Cell. Signal., 2020-074(0):109731.
PMID: 32758668 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayL Meng et al. (2020-07-31), Vital Roles of Gremlin-1 in Pulmonary Arterial Hypertension Induced by Systemic-to-Pulmonary Shunts J Am Heart Assoc, 2020-09(15):e016586.
PMID: 32750294 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAS Ibrahim et al. (2020-07-19), Bone Morphogenetic Protein (BMP)4 But Not BMP2 Disrupts the Barrier Integrity of Retinal Pigment Epithelia and Induces Their Migration: A Potential Role in Neovascular Age-Related Macular Degeneration J Clin Med, 2020-09(7).
PMID: 32707711 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA VanCleave et al. (2020-07-07), Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Oncotarget, 2020-011(27):2597-2610.
PMID: 32676162 -
Species: Mouse
Sample Types: Whole Cell
Applications: BioassayA Dudakovic et al. (2020-04-24), Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2 J. Biol. Chem., 2020-00(0).
PMID: 32332097 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayA Krouwels et al. (2020-04-14), Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration Int J Mol Sci, 2020-021(8).
PMID: 32295299 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureDA Mázala et al. (2020-03-26), TGF-&beta-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model JCI Insight, 2020-05(6).
PMID: 32213706 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Stich et al. (2020-03-21), Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades Int J Mol Sci, 2020-021(6).
PMID: 32245213 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureR Castro-Viñ et al. (2020-03-06), Generation and characterization of human induced pluripotent stem cells (iPSCs) from hand osteoarthritis patient-derived fibroblasts Sci Rep, 2020-010(1):4272.
PMID: 32144293 -
Species: N/A
Sample Types: Protein
Applications: Surface Plasmon ResonanceTJ Broekelman et al. (2020-01-27), Identification of the growth factor binding sequence in the extracellular matrix protein MAGP-1 J. Biol. Chem., 2020-00(0).
PMID: 31988245 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureHJ Zhao et al. (2019-11-28), Bone morphogenetic protein 2 induces the activation of WNT/beta-catenin signaling and human trophoblast invasion through up-regulating BAMBI Cell. Signal., 2019-10(0):109489.
PMID: 31786181 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureD Seo et al. (2019-11-01), The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway EBioMedicine, 2019-149(0):55-71.
PMID: 31685442 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureS Qin et al. (2019-11-01), Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon J Orthop Translat, 2019-122(0):101-108.
PMID: 32440505 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Omi et al. (2019-10-16), Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD signaling pathway J. Biol. Chem., 2019-10(0).
PMID: 31619522 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureLR Dutton et al. (2019-10-11), No evidence of Gremlin1-mediated activation of VEGFR2 signalling in endothelial cells J. Biol. Chem., 2019-10(0).
PMID: 31604823 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Ren et al. (2019-09-18), Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression Breast Cancer Res., 2019-021(1):109.
PMID: 31533776 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Krüger et al. (2019-09-01), Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair Int J Mol Sci, 2019-020(17).
PMID: 31480518 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Moghadasi et al. (2019-07-05), Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo Sci Rep, 2019-09(1):9750.
PMID: 31278326 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoLi et al. (2019-07-05), Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production J Orthop Translat, 2019-018(0):142-153.
PMID: 31508317 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Li et al. (2019-06-26), TGFbeta-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis Nat Commun, 2019-010(1):2795.
PMID: 31243287 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWN Addison et al. (2019-04-02), Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation Mol. Cell. Biol., 2019-00(0).
PMID: 30692273 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Rosina et al. (2019-04-01), Osteogenic differentiation of skeletal muscle progenitor cells is activated by the DNA damage response Sci Rep, 2019-09(1):5447.
PMID: 30931986 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHJ Kim et al. (2019-03-22), Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL Axis Int J Mol Sci, 2019-020(6).
PMID: 30909508 -
Species: Human
Sample Types: Bone Substitute
Applications: BioassayX Zhang et al. (2019-03-12), Osteogenic Enhancement Between Icariin and Bone Morphogenetic Protein 2: A Potential Osteogenic Compound for Bone Tissue Engineering Front Pharmacol, 2019-010(0):201.
PMID: 30914948 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Supakul et al. (2019-03-02), Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing Int J Mol Sci, 2019-020(5).
PMID: 30832329 -
Species: Chicken
Sample Types: Tissue Explants
Applications: BioassayWKW Ho et al. (2019-02-21), Feather arrays are patterned by interacting signalling and cell density waves PLoS Biol., 2019-017(2):e3000132.
PMID: 30789897 -
Species: Mouse
Sample Types: Beads
Applications: In VivoL Yu et al. (2019-02-05), BMP9 stimulates joint regeneration at digit amputation wounds in mice Nat Commun, 2019-010(1):424.
PMID: 30723209 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayT Karakida et al. (2019-02-04), Potential for Drug Repositioning of Midazolam for Dentin Regeneration Int J Mol Sci, 2019-020(3).
PMID: 30720745 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Hendrikx et al. (2019-01-29), Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2 Cell Rep, 2019-026(5):1227-1241.e6.
PMID: 30699351 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Subileau et al. (2018-12-27), Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation Stem Cell Reports, 2018-10(0).
PMID: 30595547 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Oudina et al. (2018-11-20), The paracrine effects of human induced pluripotent stem cells promote bone-like structures via the upregulation of BMP expression in a mouse ectopic model Sci Rep, 2018-18(1):17106.
PMID: 30459360 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySY Lee et al. (2018-11-16), Glucose metabolism induced by Bmp signaling is essential for murine skeletal development Nat Commun, 2018-19(1):4831.
PMID: 30446646 -
Species: Human
Sample Types: Nanoparticles
Applications: BioassayB Wang et al. (2018-11-12), Nanoparticle-modified chitosan-agarose-gelatin scaffold for sustained release of SDF-1 and BMP-2 Int J Nanomedicine, 2018-113(0):7395-7408.
PMID: 30519022 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLS Pane et al. (2018-08-30), Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer Dis Model Mech, 2018-011(9).
PMID: 30166330 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Sasa et al. (2018-07-12), Monocarboxylate transporter-1 promotes osteoblast differentiation via suppression of p53, a negative regulator of osteoblast differentiation Sci Rep, 2018-08(1):10579.
PMID: 30002387 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Koefoed et al. (2018-06-22), The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development Sci Rep, 2018-08(1):9542.
PMID: 29934521 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayYH Chung et al. (2018-05-22), BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-?1 signaling Lab. Invest., 2018-00(0).
PMID: 29789683 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Jongwattan et al. (2018-05-04), Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function Sci Rep, 2018-08(1):7022.
PMID: 29728612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Kang et al. (2018-04-11), Somatic activating mutations in MAP2K1 cause melorheostosis Nat Commun, 2018-09(1):1390.
PMID: 29643386 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Bozatzi et al. (2018-03-07), PAWS1 controls Wnt signalling through association with casein kinase 1? EMBO Rep., 2018-00(0).
PMID: 29514862 -
Species: Porcine
Sample Types: Whole Cells
Applications: BioassayDM Burmeister et al. (2018-02-18), Delivery of Allogeneic Adipose Stem Cells in Polyethylene Glycol-Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns Stem Cells Transl Med, 2018-00(0).
PMID: 29457376 -
Species: Equine
Sample Types: Whole Cells
Applications: BioassayM Desancé et al. (2018-02-10), Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 2018-019(2).
PMID: 29439436 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoJB Lees-Shepa et al. (2018-02-02), Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva Nat Commun, 2018-09(1):471.
PMID: 29396429 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Kokabu et al. (2017-12-16), BMP3 expression by osteoblast lineage cells is regulated by canonical Wnt signaling FEBS Open Bio, 2017-18(2):168-176.
PMID: 29435407 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoDW Youngstrom et al. (2017-12-15), Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects NPJ Regen Med, 2017-12(0):32.
PMID: 29302365 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMG Perino et al. (2017-12-12), Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells PLoS ONE, 2017-112(12):e0188569.
PMID: 29232368 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWS Fagg et al. (2017-12-01), Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver Cell Transplant, 2017-126(12):1868-1877.
PMID: 29390880 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Yu et al. (2017-09-05), Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-? signaling Proc. Natl. Acad. Sci. U.S.A., 2017-00(0).
PMID: 28874583 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySJ Bae et al. (2017-08-16), Acceleration of osteoblast differentiation by a novel osteogenic compound, DMP-PYT, through activation of both the BMP and Wnt pathways Sci Rep, 2017-07(1):8455.
PMID: 28814721 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Fan et al. (2017-08-08), Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2 Sci Rep, 2017-07(1):7518.
PMID: 28790361 -
Species: Human, Mouse
Sample Types: Recombinant Protein, Whole Cells
Applications: BioassayC Sallon et al. (2017-07-26), Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells J. Biol. Chem., 2017-00(0).
PMID: 28747434 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayS François et al. (2017-06-27), Synergistic effect of human Bone Morphogenic Protein-2 and Mesenchymal Stromal Cells on chronic wounds through hypoxia-inducible factor-1 ? induction Sci Rep, 2017-07(1):4272.
PMID: 28655873 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJO Múnera et al. (2017-06-22), Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling Cell Stem Cell, 2017-00(0).
PMID: 28648364 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Feng et al. (2017-06-02), BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice Development, 2017-00(0).
PMID: 28576771 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Bai et al. (2017-05-31), SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells Cell. Signal., 2017-037(0):52-61.
PMID: 28578012 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYM Lin et al. (2017-05-08), Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation Stem Cell Res Ther, 2017-08(1):93.
PMID: 28482913 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySJ Bae et al. (2017-04-15), Potent osteogenic activity of a novel imidazobenzimidazole derivative, IBIP Biochem. Biophys. Res. Commun., 2017-0487(2):409-414.
PMID: 28419840 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassayDW Hammers et al. (2017-04-01), Supraphysiological levels of GDF11 induce striated muscle atrophy EMBO Mol Med, 2017-00(0).
PMID: 28270449 -
Species: Mouse
K Breitkopf- et al. (2017-03-23), BMP-9 interferes with liver regeneration and promotes liver fibrosis Gut, 2017-00(0).
PMID: 28336518 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYan-Ting Wu (2017-03-01), Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells Mol. Hum. Reprod, 2017-00(0).
PMID: 27986931 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayO Veraitch et al. (2017-02-21), Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Sci Rep, 2017-07(0):42777.
PMID: 28220862 -
Species: Xenopus
Sample Types: Blastocele
Applications: Organoid CultureML Stevens et al. (2017-02-20), Genomic integration of Wnt/?-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional program Development, 2017-00(0).
PMID: 28219948 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Riba et al. (2017-02-15), Explicit Modeling of siRNA-Dependent On- and Off-Target Repression Improves the Interpretation of Screening Results Cell Syst, 2017-04(2):182-193.e4.
PMID: 28215525 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySV Hegarty et al. (2017-02-08), Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth Neurosci. Lett, 2017-0643(0):32-37.
PMID: 28188849 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Sripathy et al. (2017-01-31), Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-? superfamily as a regulator of XIST expression Proc. Natl. Acad. Sci. U.S.A, 2017-00(0).
PMID: 28143937 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Jung et al. (2017-01-19), Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells Stem Cells Int, 2017-02017(0):7859184.
PMID: 28197209 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-12-15), Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication PLoS ONE, 2016-111(12):e0168334.
PMID: 27977771 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayG B de Souza (2016-12-07), Bovine ovarian stem cells differentiate into germ cells and oocyte-like structures after culture in vitro Reprod. Domest. Anim, 2016-10(0).
PMID: 27925309 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-12-06), Regulation of hepcidin expression by inflammation-induced activin B Sci Rep, 2016-16(0):38702.
PMID: 27922109 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAtakan Tevlek (2016-11-27), Bi-layered constructs of poly(glycerol-sebacate)-?-tricalcium phosphate for bone-soft tissue interface applications Mater Sci Eng C Mater Biol Appl, 2016-172(0):316-324.
PMID: 28024592 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016-11-11), Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6 Nat Commun, 2016-17(0):13247.
PMID: 27834400 -
Species: Rat
Sample Types: In Vivo
Applications: In Vivo(2016-08-16), Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow-derived counterparts J Tissue Eng, 2016-07(0):2041731416661.
PMID: 27579159 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKatsuhiro Hiranuma et al. (2016-07-13), Expression of nephronectin is enhanced by 1?,25-dihydroxyvitamin D3. FEBS Open Bio, 2016-00(0):2211-5463.
PMID: 27642554 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRachel Ruoff (2016-06-16), Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP Proc Natl Acad Sci USA, 2016-00(0).
PMID: 27313212 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCM Karner et al. (2016-04-20), Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation J. Biol. Chem., 2016-0291(25):13028-39.
PMID: 27129247 -
Species: Transgenic Mouse
Sample Types: Recombinant Protein
Applications: BioassayChang C et al. (2015-09-17), Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating. PLoS ONE, 2015-010(9):e0137017.
PMID: 26379273 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCruet-Hennequart S et al. (2015-04-02), Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE, 2015-010(3):e0119334.
PMID: 25837977 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWesthrin M et al. (2015-03-13), Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices. PLoS ONE, 2015-010(3):e0120374.
PMID: 25769043 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNio-Kobayashi J et al. (2015-01-30), Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum. Endocrinology, 2015-0156(4):1494-503.
PMID: 25635621 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMalhotra et al. (2015-01-20), Inhibition of bone morphogenetic protein signal transduction prevents the medial vascular calcification associated with matrix Gla protein deficiency. PLoS ONE, 2015-010(1):e0117098.
PMID: 25603410 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAlberton P et al. (2014-12-10), Loss of tenomodulin results in reduced self-renewal and augmented senescence of tendon stem/progenitor cells. Stem Cells Dev, 2014-124(5):597-609.
PMID: 25351164 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHill C et al. (2014-12-01), Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn, 2014-1244(2):122-33.
PMID: 25382630 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPrewitt A et al. (2014-11-19), Heterozygous null bone morphogenetic protein receptor type 2 mutations promote SRC kinase-dependent caveolar trafficking defects and endothelial dysfunction in pulmonary arterial hypertension. J Biol Chem, 2014-1290(2):960-71.
PMID: 25411245 -
Species: Chicken, Mouse
Sample Types: Whole Cells
Applications: BioassayYang X et al. (2014-10-20), Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem, 2014-1289(50):34768-79.
PMID: 25331953 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTanwar V et al. (2014-07-01), Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway. Stem Cells, 2014-032(7):1774-88.
PMID: 24648383 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBizen N et al. (2014-06-01), A growth-promoting signaling component cyclin D1 in neural stem cells has antiastrogliogenic function to execute self-renewal. Stem Cells, 2014-032(6):1602-15.
PMID: 24302516 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPark J et al. (2014-04-30), Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis. Mol Cancer Res, 2014-012(8):1088-99.
PMID: 24784840 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShen et al. (2014-03-28), Tissue engineering bone using autologous progenitor cells in the peritoneum. PLoS ONE, 2014-09(3):e93514.
PMID: 24681529 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOkamoto M et al. (2014-03-27), Noncanonical Wnt5a enhances Wnt/beta-catenin signaling during osteoblastogenesis. Sci Rep, 2014-04(0):4493.
PMID: 24670389 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDussiot M et al. (2014-03-23), An activin receptor IIA ligand trap corrects ineffective erythropoiesis in beta-thalassemia. Nat Med, 2014-020(4):398-407.
PMID: 24658077 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHeinonen A et al. (2014-03-11), Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7. BMC Neurosci, 2014-015(0):38.
PMID: 24618040 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAbdel Aziz M et al. (2014-03-09), The role of bone marrow derived-mesenchymal stem cells in attenuation of kidney function in rats with diabetic nephropathy. Diabetol Metab Syndr, 2014-06(1):34.
PMID: 24606996 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTodaro M et al. (2014-03-06), CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell, 2014-014(3):342-56.
PMID: 24607406 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAn J et al. (2014-03-01), Changes of microRNA profile and microRNA-mRNA regulatory network in bones of ovariectomized mice. J Bone Miner Res, 2014-029(3):644-56.
PMID: 23929739 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWolf S et al. (2014-02-27), Identification of BMP2 as an epigenetically silenced growth inhibitor in rhabdomyosarcoma. Int J Oncol, 2014-044(5):1727-35.
PMID: 24585058 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao X et al. (2014-02-21), Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE, 2014-09(2):e89114.
PMID: 24586530 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySuresh Babu S et al. (2014-02-20), TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer, 2014-014(0):113.
PMID: 24555435 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRatnayake M et al. (2014-01-21), Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE, 2014-09(1):e86590.
PMID: 24466161 -
Species: Hamster
Sample Types: Whole Cells
Applications: BioassayHang et al. (2013-12-12), Asparagine-linked glycosylation of bone morphogenetic protein-2 is required for secretion and osteoblast differentiation. Glycobiology, 2013-124(3):292-304.
PMID: 24336949 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBrady K et al. (2013-12-04), Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 2013-123(5):541-54.
PMID: 24172175 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayGarrel G et al. (2013-11-18), Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHbeta gene expression. Endocrinology, 2013-1155(2):592-604.
PMID: 24248462 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayClementi C et al. (2013-11-14), Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet, 2013-19(11):e1003863.
PMID: 24244176 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao L et al. (2013-10-21), TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. J Cell Sci, 2013-1126(0):5704-13.
PMID: 24144697 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKawamoto T et al. (2013-10-16), Generation of robust vascular networks from cardiovascular blast populations derived from human induced pluripotent stem cells in vivo and ex vivo organ culture system. Biochem Biophys Res Commun, 2013-1441(1):180-5.
PMID: 24140407 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLaperrousaz B et al. (2013-10-07), Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression. Blood, 2013-1122(23):3767-77.
PMID: 24100446 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTalavera-Adame et al. (2013-09-24), Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev, 2013-022(24):3252-60.
PMID: 23924071 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHwang J et al. (2013-09-19), Protein phosphatase 2A isoforms utilizing Abeta scaffolds regulate differentiation through control of Akt protein. J Biol Chem, 2013-0288(44):32064-73.
PMID: 24052256 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAubert-Foucher E et al. (2013-09-17), A unique tool to selectively detect the chondrogenic IIB form of human type II procollagen protein. Matrix Biol, 2013-034(0):80-8.
PMID: 24055103 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKoskinen C et al. (2013-08-29), Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein alpha (SIRPalpha) signaling. J Biol Chem, 2013-0288(41):29333-44.
PMID: 23990469 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGadi et al. (2013-07-25), The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem, 2013-0288(35):25400-13.
PMID: 23888050 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDeschaseaux F et al. (2013-04-16), Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue. FASEB J, 2013-027(8):2977-87.
PMID: 23592762 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang et al. (2013-04-01), Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS ONE, 2013-08(4):e60244.
PMID: 23560082 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLi S et al. (2013-03-25), Integration of multiple signaling regulates through apoptosis the differential osteogenic potential of neural crest-derived and mesoderm-derived Osteoblasts. PLoS ONE, 2013-08(3):e58610.
PMID: 23536803 -
Species: Bovine
Sample Types: Whole Cells
Applications: BioassayGlister C et al. (2013-03-25), Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production. Proc Natl Acad Sci U S A, 2013-0110(15):E1426-35.
PMID: 23530236 -
Species: Mouse
Sample Types: Embryo
Applications: In VivoYamamoto-Shiraishi Y et al. (2013-03-13), Wnt and BMP signaling cooperate with Hox in the control of Six2 expression in limb tendon precursor. 2013-00(0).
PMID: 23499659 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHuegel J et al. (2013-03-01), Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol, 2013-0377(1):100-12.
PMID: 23458899 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNarayanan et al. (2013-02-06), Human embryonic stem cells differentiate into functional renal proximal tubular-like cells. Kidney Int, 2013-083(4):593-603.
PMID: 23389418 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAkiyama H et al. (2013-01-21), A novel adipokine C1q/TNF-related protein 1 (CTRP1) regulates chondrocyte proliferation and maturation through the ERK1/2 signaling pathway. Mol Cell Endocrinol, 2013-0369(1):63-71.
PMID: 23348620 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen et al. (2012-12-02), H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 2012-145(1):34-42.
PMID: 23202127 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceWu et al. (2012-09-27), Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE, 2012-07(9):e46307.
PMID: 23029472 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySatomi-Kobayashi S et al. (2012-07-09), Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER). J Biol Chem, 2012-0287(36):30336-45.
PMID: 22778264 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassayBruce D et al. (2012-07-07), Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway. Cell Signal, 2012-024(11):1999-2006.
PMID: 22781750 -
Species: Human
Sample Types: Recombinant Protein
Applications: Binding AssayKim M et al. (2012-04-13), Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion. PLoS ONE, 2012-07(4):e35100.
PMID: 22514712 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayAsumda FZ et al. (2011-10-12), Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol., 2011-112(0):44.
PMID: 21992089 -
Species: Human, Mouse
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceCastonguay R et al. (2011-07-07), Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 2011-0286(34):30034-46.
PMID: 21737454 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGeens M et al. (2011-02-12), Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells. J. Assist. Reprod. Genet., 2011-00(0).
PMID: 21318592 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDalfino G et al. (2010-04-29), Bone morphogenetic protein-2 may represent the molecular link between oxidative stress and vascular stiffness in chronic kidney disease. Atherosclerosis, 2010-0211(2):418-23.
PMID: 20537331 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHaupt LM et al. (2009-09-01), The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis. J. Cell. Physiol., 2009-0220(3):780-91.
PMID: 19479939 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTanno T et al. (2009-05-04), Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood, 2009-0114(1):181-6.
PMID: 19414861 -
Species: Zebrafish
Sample Types: Whole Tissue
Applications: BioassayLittle SC et al. (2009-04-19), Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat. Cell Biol., 2009-011(5):637-43.
PMID: 19377468 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIrie N et al. (2009-03-19), Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J. Biol. Chem., 2009-0284(21):14637-44.
PMID: 19299512 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShafer SL et al. (2009-01-21), Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol., 2009-046(5):621-35.
PMID: 19344627 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTseng YH et al. (2008-08-21), New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature, 2008-0454(7207):1000-4.
PMID: 18719589 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJeanpierre S et al. (2008-07-29), BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood, 2008-0112(8):3154-63.
PMID: 18664625 -
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA (Capture), Surface Plasmon ResonanceSengle G et al. (2008-07-02), A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J. Mol. Biol., 2008-0381(4):1025-39.
PMID: 18621057 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKane R et al. (2008-06-20), Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol. Vis., 2008-014(0):1138-48.
PMID: 18587495 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDesbordes SC et al. (2008-06-05), High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell, 2008-02(6):602-12.
PMID: 18522853 -
Species: Human
Sample Types: Recombinant Protein
Applications: Binding Assay, Surface Plasmon ResonanceSengle G et al. (2008-03-13), Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem., 2008-0283(20):13874-88.
PMID: 18339631 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySouthwood M et al. (2008-01-01), Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J. Pathol., 2008-0214(1):85-95.
PMID: 17992660 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPi X et al. (2007-12-24), Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors. J. Cell Biol., 2007-1179(7):1569-82.
PMID: 18158328 -
Species: Xenopus
Sample Types: Whole Cells
Applications: BioassayHocking JC et al. (2007-10-05), TGFbeta ligands promote the initiation of retinal ganglion cell dendrites in vitro and in vivo. Mol. Cell. Neurosci., 2007-137(2):247-60.
PMID: 17997109 -
Species: Xenopus
Sample Types: Whole Cells
Applications: BioassayWen Z et al. (2007-07-02), BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J. Cell Biol., 2007-0178(1):107-19.
PMID: 17606869 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNiki Y et al. (2007-07-01), Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J. Immunol., 2007-0179(1):639-46.
PMID: 17579086 -
Species: Human, Mouse
Sample Types: Whole Cells
Applications: BioassayTesar PJ et al. (2007-06-27), New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 2007-0448(7150):196-9.
PMID: 17597760 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLin L et al. (2007-05-31), Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood, 2007-0110(6):2182-9.
PMID: 17540841 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayUngefroren H et al. (2007-04-15), Antitumor activity of ALK1 in pancreatic carcinoma cells. Int. J. Cancer, 2007-0120(8):1641-51.
PMID: 17230504 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDiarra D et al. (2007-01-21), Dickkopf-1 is a master regulator of joint remodeling. Nat. Med., 2007-013(2):156-63.
PMID: 17237793 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhu J et al. (2007-01-16), Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood, 2007-0109(9):3706-12.
PMID: 17227831 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGossrau G et al. (2007-01-11), Bone morphogenetic protein-mediated modulation of lineage diversification during neural differentiation of embryonic stem cells. Stem Cells, 2007-025(4):939-49.
PMID: 17218404 -
Species: Canine, Human
Sample Types: Whole Cells
Applications: BioassayBartunek J et al. (2006-10-20), Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. Am. J. Physiol. Heart Circ. Physiol., 2006-1292(2):H1095-104.
PMID: 17056665 -
Species: Bovine, Human
Sample Types: Whole Cells
Applications: BioassayYao Y et al. (2006-09-27), Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells. Cardiovasc. Res., 2006-074(2):279-89.
PMID: 17074310 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLindsley RC et al. (2006-08-30), Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 2006-0133(19):3787-96.
PMID: 16943279 -
Species: Rabbit
Sample Types: In Vivo
Applications: In VivoLiu HW et al. (2006-06-16), Targeted delivery system for juxtacrine signaling growth factor based on rhBMP-2-mediated carrier-protein conjugation. Bone, 2006-039(4):825-36.
PMID: 16782421 -
Species: Chicken
Sample Types: In Vivo
Applications: In VivoBonafede A et al. (2006-06-15), BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression. Dev. Biol., 2006-0299(2):330-44.
PMID: 17005177 -
Species: Rat
Sample Types: Whole Tissue
Applications: BioassayMaeshima A et al. (2006-04-27), Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev. Biol., 2006-0295(2):473-85.
PMID: 16643884 -
Species: Chicken
Sample Types: Whole Tissue
Applications: BioassaySchlueter J et al. (2006-04-01), BMP is an important regulator of proepicardial identity in the chick embryo. Dev. Biol., 2006-0295(2):546-58.
PMID: 16677627 -
Species: Rat
Sample Types: In Vivo
Applications: In VivoHong SJ et al. (2006-03-29), The effect of a fibrin-fibronectin/beta-tricalcium phosphate/recombinant human bone morphogenetic protein-2 system on bone formation in rat calvarial defects. Biomaterials, 2006-027(20):3810-6.
PMID: 16574220 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAndo T et al. (2006-01-01), TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res. Ther., 2006-08(5):R146.
PMID: 16945157 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBlair DG et al. (2004-11-15), Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis. J. Immunol., 2004-1173(10):5914-7.
PMID: 15528323 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKnosp WM et al. (2004-09-01), HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis. Development, 2004-0131(18):4581-92.
PMID: 15342482 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBinnerts ME et al. (2004-03-05), Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins. Biochem. Biophys. Res. Commun., 2004-0315(2):272-80.
PMID: 14766204 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMoser M et al. (2003-08-01), BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol. Cell. Biol., 2003-023(16):5664-79.
PMID: 12897139 -
Species: Rabbit
Sample Types: Whole Cells
Applications: BioassayLee YM et al. (2003-06-01), Enhanced bone augmentation by controlled release of recombinant human bone morphogenetic protein-2 from bioabsorbable membranes. J. Periodontol., 2003-074(6):865-72.
PMID: 12886998
There are no citations that match your criteria.
Customer Reviews for Recombinant Human/Mouse/Rat BMP-2 Protein (11)
Customer Images
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Application: Enzymatic activity in vitroReason for Rating: 50 ng/ml works well to induce osteoblast differentiation.Verified Customer | Posted 04/05/2022
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Application: Stem/Immune cell maintenance or differentiationReason for Rating: I used it for osteoblasts differentiation, Arizarin staining.It keeps and promotes osteoblasts mineralization very well.Verified Customer | Posted 05/27/2021
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Application: In vitro bioactivity in cell cultureReason for Rating: I used BMP2 to activate BMP reporter and it worked very well.Verified Customer | Posted 09/15/2020
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Application: CellProlifReason for Rating: Another great product made by R&D Systems. Always produces consistent and reliable results. Great as a control.Verified Customer | Posted 10/09/2019
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Application: ImmunofluorescenceVerified Customer | Posted 10/26/2018
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Application: In vitro bioactivity in cell cultureReason for Rating: Performed as expected to force differentiation of C2C12's to OsteoblastsVerified Customer | Posted 09/07/2017
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Verified Customer | Posted 05/03/2017
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Application: BMP-2 Delivery SystemVerified Customer | Posted 01/05/2017
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Application: Binding assay/Protein-protein interactionReason for Rating: Materials performed as expected.Verified Customer | Posted 05/13/2016
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Application: Binding assay/Protein-protein interactionReason for Rating: This protein performed exactly as expected.Verified Customer | Posted 01/15/2016
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Sample Tested: C2C12 mouse myoblast cell lineVerified Customer | Posted 10/26/2015ALP assay measuring osteogenic induction of C2C12 cells treated with BMP-2.
There are no reviews that match your criteria.
FAQs for Recombinant Human/Mouse/Rat BMP-2 Protein
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What is the difference between the two Recombinant Human/Mouse/Rat BMP-2 Proteins (Catalog # 355-BM and 355-BEC)?
Catalog # 355-BM is produced in a mammalian system using CHO cells and exhibits better activity in our routine QC bioassay, while Catalog # 355-BEC is produced in an E. coli expression system and is less expensive. Bioactivity of both Human/Mouse/Rat BMP-2 Proteins is measured in an alkaline phosphatase assay using by ATDC5 mouse chondrogenic cells. For 355-BM, the ED50 for this effect is 40-200 ng/mL, while for 355-BEC, the ED50 range is 80-480 ng/mL. We recommend reviewing our list of publications under the Citations tab for both 355-BM and 355-BEC to determine which of the two proteins is most suitable for your experiment.
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What is the sequence homology between human, mouse and rat BMP-2
Mature human BMP-2 shares 100% aa sequence identity with mouse and rat BMP-2.
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Does Recombinant Human/Mouse/Rat BMP-2 Protein (Catalog # 355-BM) have a histidine tag?
Recombinant Human/Mouse/Rat BMP-2 Protein (Catalog # 355-BM) does not contain a histidine tag. The sequence of this protein contains Gln283-Arg396 aa based on Accession # P12643.