Recombinant Human Mcl-1 Western Blot Standard Protein
R&D Systems, part of Bio-Techne | Catalog # WBC003
Key Product Details
- R&D Systems E. coli-derived Recombinant Human Mcl-1 Western Blot Standard Protein (WBC003)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
Sf 21 (baculovirus)
Conjugate
Unconjugated
Applications
Western Blot
Formulation, Preparation and Storage
WBC003
Background: Mcl-1
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
Long Name
Myeloid Cell Leukemia Sequence 1
Alternate Names
BCL2L3, Mcl1
Gene Symbol
MCL1
Additional Mcl-1 Products
Product Documents for Recombinant Human Mcl-1 Western Blot Standard Protein
Product Specific Notices for Recombinant Human Mcl-1 Western Blot Standard Protein
For research use only
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