Recombinant Human BMP-2/BMP-7 Heterodimer Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | E. coli |
Accession #: | NP_001191 (BMP-2) & NP_001710 (BMP-7) |
Structure / Form: | Disulfide-linked heterodimer |
Applications: | Bioactivity |
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Citations for Recombinant Human BMP-2/BMP-7 Heterodimer Protein (17)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human BMP-2/BMP-7 Heterodimer Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayYS Yang et al. (2022), Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery Oncogene, 13(1):6175.
PMID: 36258013 -
Species: Zebrafish
Sample Types: Embryo
Applications: BioassayH Greenfeld et al. (2021), The BMP signaling gradient is interpreted through concentration thresholds in dorsal-ventral axial patterning PloS Biology, 19(1):e3001059.
PMID: 33481775 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoJM Kim et al. (2020), A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation Nat Commun, 11(1):2289.
PMID: 32385263 -
Species: Human
Sample Types: Whole Tissue
Applications: BioassayA Krouwels et al. (2020), Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration Int J Mol Sci, 21(8).
PMID: 32295299 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySEJ Tanis et al. (2019), BLNCR is a long non-coding RNA adjacent to integrin beta-1 that is rapidly lost during epidermal progenitor cell differentiation Sci Rep, 9(1):31.
PMID: 30631104 -
Species: Chicken
Sample Types: Tissue Explants
Applications: BioassayWKW Ho et al. (2019), Feather arrays are patterned by interacting signalling and cell density waves PLoS Biol., 17(2):e3000132.
PMID: 30789897 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAM El-Naggar et al. (2019), HACE1 is a potential tumor suppressor in osteosarcoma Cell Death Dis, 10(1):21.
PMID: 30622235 -
Applications: ELISA (Standard)LD Loozen et al. (2018), Bone formation by heterodimers through non-viral gene delivery of BMP-2/6 and BMP-2/7 Eur Cell Mater, 35(0):195-208.
PMID: 29589649 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Bi et al. (2018), All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity Cell Biosci, 8(0):48.
PMID: 30159139 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySEJ Tanis et al. (2018), Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation Cell Rep, 25(5):1292-1303.e5.
PMID: 30380419 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Choudhary et al. (2017), Directing Differentiation of Pluripotent Stem Cells Toward Retinal Pigment Epithelium Lineage Stem Cells Transl Med, 6(2):490-501.
PMID: 28191760 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayGreenblatt M et al. (2015), p38alpha MAPK is required for tooth morphogenesis and enamel secretion. J Biol Chem, 290(1):284-95.
PMID: 25406311 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOchiai-Shino H et al. (2014), A novel strategy for enrichment and isolation of osteoprogenitor cells from induced pluripotent stem cells based on surface marker combination. PLoS ONE, 9(6):e99534.
PMID: 24911063 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGoldie S et al. (2012), FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res, 72(13):3424-36.
PMID: 22564525 -
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon ResonanceCastonguay R et al. (2011), Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth. J. Biol. Chem., 286(34):30034-46.
PMID: 21737454 -
Species: Zebrafish
Sample Types: Whole Tissue
Applications: BioassayLittle SC et al. (2009), Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat. Cell Biol., 11(5):637-43.
PMID: 19377468 -
Species: Zebrafish
Sample Types: In Vivo
Applications: In VivoEsterberg R et al. (2008), Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm. Development, 135(23):3891-901.
PMID: 18948415
There are no citations that match your criteria.
FAQs for Recombinant Human BMP-2/BMP-7 Heterodimer Protein
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What is the half-life of a recombinant or natural protein in culture at 37 °C?
R&D Systems has not determined the half-life of recombinant or natural proteins in culture. For cell-based bioassays, the incubation period of the protein with the cells typically ranges from 48 to 96 hours. Assay conditions for each protein will need to be optimized by each researcher.