Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Novus Biologicals, part of Bio-Techne | Catalog # H00003625-T02
Key Product Details
Species
Human
Applications
Western Blot
Product Summary for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Quality control test: Transient overexpression cell lysate was tested with Anti-INHBB antibody by Western Blots. Plasmid: pCMV-INHBB full-length
Product Specifications
Specificity
Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate(Denatured)
Type
293T Cell Transient Overexpression
Protein State
Denatured
Formulation, Preparation, and Storage
Formulation
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Concentration
mg/ml
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -80C. Avoid freeze-thaw cycles.
Background: Activin B
Activin B is a TGF-beta superfamily cytokine that regulates cellular migration by inducing actin stress fiber formation. It signals through heterodimeric receptor complexes composed of type I (Activin RIA or RIB) and type II (Activin RIIA or RIIB) transmembrane Ser/Thr kinases. It also modulates signaling through E-Cadherin and Integrin beta 3. Activin B upregulation is associated with tumor cell adhesion, migration, and metastasis. It also promotes wound healing through increased cellular migration. Activin B additionally induces hair follicle formation and expression of Hepicin in the liver, but it inhibits lipolysis in adipocytes and glucose-stimulated calcium influx in pancreatic beta cells. Alterations of Activin B serum levels of Activin B are associated with ectopic pregnancy and chronic fatigue syndrome, and it is upregulated in alveolar epithelial cells in pulmonary fibrosis.
Alternate Names
activin AB beta polypeptide, Activin Beta B, Activin beta-B chain, INHBB, Inhibin Beta B, inhibin beta B chain, Inhibin Subunit Beta B, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2
Gene Symbol
INHBB
Additional Activin B Products
Product Documents for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
Product Specific Notices for Activin B/Inhibin beta B 293T Cell Transient Overexpression Lysate
This product is produced by and distributed for Abnova, a company based in Taiwan.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.
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