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I have many samples and my schedule is tightMaurice S. produces size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice S. a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too. |
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My current method is not reproducible and error-proneMaurice S. employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required. |
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I work in a GMP lab and data integrity is key to my compliance requirementCompass for iCE, the software package Maurice S. uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment. |
View all citations for the Imaged Capillary Electrophoresis (iCE) platform.
Please visit our Instrument Citation Database to search our collection of scientific articles that feature our instruments.
"For charge variant analysis, we have largely replaced ion exchange chromatography with the icIEF on the Maurice system….. Once we brought it in-house, it was the ideal platform for us - the icIEF fractionation capability enabled us to get further insights into the charge variants."
Arnaud Delobel, PhD, Director, R&D and Innovation Quality Assistance
"Imaged cIEF, also known as icIEF, is a platform analytical technology and offers not only high throughput with a quick turn-around of ~10-min per sample, but also quantitation capability for charge variants, while maintaining the highest resolution of IEF technology."
Xiaoping He, Sr. Principal Scientist, Pfizer (retired)
"Adding fractionation capabilities can really help in simplifying the workflow to assess peak identity, especially if paired with state-of-the-art mass spectrometry techniques. On top of this, the experience of working with the Bio-Techne family has been a pleasure so far and they helped us throughout our first work, beyond the training aspect of the installation."
Dr. Sara Carillo, Bioanalytical Research Lead, NIBRT
"Replacing preparative chromatography with MauriceFlex has made the process of fraction collection more efficient."
Amreen Jonas, Principal Associate Scientist, Mersana Therapeutics
"I think that the data we produced [on Maurice] shows excellent quality, due to the precise and reliable Maurice instrument."
Professor Hermann Wätzig, Technical University of Braunschweig in Germany
| Feature | CE-SDS Specification |
|---|---|
| Minimum Sample Volume | 50 µL |
| Sample Delivery | Electrokinetic |
| Typical Separation Time | Reduced IgG: 25 min, Non-reduced IgG: 35 min |
| Detection Capability | UV Absorbance at 220 nm |
| Typical Voltage | Separation: 5750 V |
| Sample Injections per Cartridge | 100 guaranteed, 200 maximum for CE-SDS, 500 maximum for CE-SDS PLUS |
| Maximum Sample Injections per Batch | 48 |
| Size Range | 10–270 kDa |
| Sizing CV | ≤2% |
| Relative Migration Time CV | <1% for reduced IgG |
| Sizing Resolution | ≥1.5 for NGHC/HC IgG Standard |
| Dynamic Range | 2 logs |
| Linearity | >0.995 |
| Sensitivity (LOD) | 0.3 µg/mL (Value based on Internal Standard) |
| Sample Tray Options | 96-well plates or 48 vials |
| Dimensions | 44cm H x 42cm W x 61cm D |
| Weight | 46 kg (100 lb) |
