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IgG purity and heterogeneity
IgG purity and heterogeneity
Maurice S. simplifies your size separations workflow by cutting out all the optimization guesswork. His ready-to-go CE-SDS or CE-SDS PLUS cartridges give you IgG purity data in 35 minutes. The best part? Get method development done in a day—platform methods too! Now you can run all your antibodies to get the purity data, heavy and light chain content and HC vs. NGHC composition you need.
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I have many samples and my schedule is tightMaurice S. produces size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice S. a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too. |
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My current method is not reproducible and error-proneMaurice S. employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required. |
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I work in a GMP lab and data integrity is key to my compliance requirementCompass for iCE, the software package Maurice S. uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment. |
More Information About Maurice S.
| Feature | CE-SDS Specification |
|---|---|
| Minimum Sample Volume | 50 µL |
| Sample Delivery | Electrokinetic |
| Typical Separation Time | Reduced IgG: 25 min, Non-reduced IgG: 35 min |
| Detection Capability | UV Absorbance at 220 nm |
| Typical Voltage | Separation: 5750 V |
| Sample Injections per Cartridge | 100 guaranteed, 200 maximum for CE-SDS, 500 maximum for CE-SDS PLUS |
| Maximum Sample Injections per Batch | 48 |
| Size Range | 10–270 kDa |
| Sizing CV | ≤2% |
| Relative Migration Time CV | <1% for reduced IgG |
| Sizing Resolution | ≥1.5 for NGHC/HC IgG Standard |
| Dynamic Range | 2 logs |
| Linearity | >0.995 |
| Sensitivity (LOD) | 0.3 µg/mL (Value based on Internal Standard) |
| Sample Tray Options | 96-well plates or 48 vials |
| Dimensions | 44cm H x 42cm W x 61cm D |
| Weight | 46 kg (100 lb) |
