(R)-Baclofen
Tocris Bioscience, part of Bio-Techne | Catalog # 0796
Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
Key Product Details
Description
Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
Alternative Names
STX 209
Product Description
More active enantiomer of (RS)-Baclofen, a selective GABAB agonist.Racemate also available.
Product Specifications
Molecular Weight
213.66
Formula
C10H12ClNO2
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
(R)-4-Amino-3-(4-chlorophenyl)butanoic acid
CAS Number
69308-37-8
PubChem ID
44602
InChI Key
KPYSYYIEGFHWSV-QMMMGPOBSA-N
SMILES
NC[C@@](CC(O)=O)([H])C1=CC=C(Cl)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 4.27 | 20 with gentle warming |
Preparing Stock Solutions
for (R)-Baclofen
The following data is based on the product molecular weight 213.66
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 23.40 mL | 117.01 mL | 234.02 mL |
| 1 mM | 4.68 mL | 23.40 mL | 46.80 mL |
| 2 mM | 2.34 mL | 11.70 mL | 23.40 mL |
| 10 mM | 0.47 mL | 2.34 mL | 4.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hong Effects of phaclofen and the enantiomers of bac. on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur.J.Pharmacol. 1991 PMID: 1654254
- Falch Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J.Neurochem. 1986 PMID: 3016189
Product Specific Notices for (R)-Baclofen
For research use only
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