Mouse IL-6 DuoSet ELISA

Name: Mouse IL-6 DuoSet ELISA
Brand: R&D Systems
SKU: DY406
Rating: 5 (34 reviews)

R&D Systems, Inc. a Bio-Techne Brand

Catalog # DY406

Citations (515)

(34)

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Key Product Details

Assay Type:	Solid Phase Sandwich ELISA
Assay Range:	15.6 - 1,000 pg/mL
Sample Types:	Cell culture supernates, serum, and plasma Note: Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet
Mouse IL-6 DuoSet ELISA Features:	Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time Development protocols are provided to guide further assay optimization Assay can be customized to your specific needs Economical alternative to complete kits

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Summary for Mouse IL-6 DuoSet ELISA

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-6. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Specifications for Mouse IL-6 DuoSet ELISA

Assay Format	96-well strip plate (sold separately)
Sample Volume Required	100 µL
Reactivity	Mouse
Specificity	Please see the product datasheet
Detection Method	Colorimetric ELISA - 450nm (TMB)
Conjugate	Biotin
Label	HRP
Measurement	Quantitative ELISA
Sufficient Materials	For five or fifteen 96-well plates*

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Kit Contents for Mouse IL-6 DuoSet ELISA

Capture Antibody
Detection Antibody
Recombinant Standard
Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data Examples for Mouse IL-6 DuoSet ELISA

	Mouse IL-6 ELISA Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-6

Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.

IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor.

IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.

Item	Value
Long Name	Interleukin 6
Entrez Gene IDs	3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 102138971 (Cynomolgus Monkey); 100034196 (Equine); 493687 (Feline); 463288 (Primate); 100008733 (Rabbit)
Alternate Names	B-cell differentiation factor, B-cell stimulatory factor 2, BSF-2, BSF2, CDF, CTL differentiation factor , HSF, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, MGI-2A, hybridoma growth factor, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6

Citations for Mouse IL-6 DuoSet ELISA (515)

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Citations are publications that use Bio-Techne products. Selected citations for Mouse IL-6 DuoSet ELISA include:

Species: Mouse
Sample Types: Cell Culture Supernates

L Chen et al. (2022), Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction Bioactive materials, 10(0):420-429.
PMID: 34901557
Species: Mouse
Sample Types: Serum

GS McElroy et al. (2022), Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice Scientific Reports, 12(1):5196.
PMID: 35338200
Species: Mouse
Sample Types: Cell Culture Supernates

W Kazana et al. (2022), A Novel Mechanism of Macrophage Activation by the Natural Yolkin Polypeptide Complex from Egg Yolk International Journal of Molecular Sciences, 23(6).
PMID: 35328547
Species: Mouse
Sample Types: Cell Culture Supernates

C Iuliano et al. (2022), Fetal Tissue-Derived Mast Cells (MC) as Experimental Surrogate for In Vivo Connective Tissue MC Cells, 11(6).
PMID: 35326379
Species: Mouse
Sample Types: Cell Culture Supernates

E Singh et al. (2022), Poly epsilon-Caprolactone Nanoparticles for Sustained Intra-Articular Immune Modulation in Adjuvant-Induced Arthritis Rodent Model Pharmaceutics, 14(3).
PMID: 35335895
Species: Mouse
Sample Types: Cell Culture Supernates

XAMH van Dieren et al. (2022), Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages Proceedings of the National Academy of Sciences of the United States of America, 119(12):e2114739119.
PMID: 35302892
Species: Mouse
Sample Types: Tissue Homogenates

PATS Castro et al. (2022), Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice PLoS ONE, 17(1):e0261667.
PMID: 35061737
Species: Mouse
Sample Types: Cell Culture Supernates

MA Pallett et al. (2022), DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation Viruses, 14(2).
PMID: 35215908
Species: Mouse
Sample Types: BALF

Y Gu et al. (2022), MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema Oxidative Medicine and Cellular Longevity, 2022(0):9300269.
PMID: 35035670
Species: Mouse
Sample Types: Cell Culture Supernates

F Scopelliti et al. (2022), The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands Journal of leukocyte biology, 0(0).
PMID: 35199885
Species: Mouse
Sample Types: Tissue Homogenates

A Nemmar et al. (2022), The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis Biomedicines, 10(1).
PMID: 35052780
Species: Mouse
Sample Types: Cell Culture Supernates

A Skopál et al. (2022), Cathepsin D interacts with adenosine A2A receptors in mouse macrophages to modulate cell surface localization and inflammatory signaling The Journal of Biological Chemistry, 0(0):101888.
PMID: 35367412
Species: Mouse
Sample Types: Cell Culture Supernates

R Pohl et al. (2022), Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 10(1).
PMID: 35052810
Species: Mouse
Sample Types: Cell Culture Supernates

R Giri et al. (2022), Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation Cell Reports, 39(2):110646.
PMID: 35417687
Species: Mouse
Sample Types: Cell Culture Supernates

MMS Hamoud et al. (2022), Design and Synthesis of Novel 1,3,4-Oxadiazole and 1,2,4-Triazole Derivatives as Cyclooxygenase-2 Inhibitors with Anti-inflammatory and Antioxidant activity in LPS-stimulated RAW264.7 Macrophages Bioorganic chemistry, 124(0):105808.
PMID: 35447409
Species: Mouse
Sample Types: Cell Culture Supernates

I Park et al. (2022), C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis Nature Communications, 13(1):215.
PMID: 35017526
Species: Mouse
Sample Types: Cell Culture Supernates

YH Su et al. (2022), Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice International Journal of Molecular Sciences, 23(7).
PMID: 35409371
Species: Mouse
Sample Types: Cell Culture Supernates

M Holthaus et al. (2022), The Secretome of Preconditioned Mesenchymal Stem Cells Drives Polarization and Reprogramming of M2a Macrophages toward an IL-10-Producing Phenotype International Journal of Molecular Sciences, 23(8).
PMID: 35456922
Species: Mouse
Sample Types: BALF

KC Ngamsri et al. (2022), Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1 Cells, 11(7).
PMID: 35406657
Species: Mouse
Sample Types: Bronchoalveolar lavage fluid

EC Dominguez et al. (2022), Aspirin-Triggered Resolvin D1 Reduces Chronic Dust-Induced Lung Pathology without Altering Susceptibility to Dust-Enhanced Carcinogenesis Cancers, 14(8).
PMID: 35454807
Species: Mouse
Sample Types: Cell Culture Supernates

C Lemberg et al. (2022), Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation PloS Pathogens, 18(4):e1010012.
PMID: 35404986
Species: Mouse
Sample Types: Cell Culture Supenates

M Arabpour et al. (2022), ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection Mucosal Immunology, 0(0).
PMID: 35418673
Species: Mouse
Sample Types: cell culture

Y Hiramatsu et al. (2022), The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model MBio, 0(0):e0319721.
PMID: 35357202
Species: Mouse
Sample Types: BALF

A Moshensky et al. (2022), Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice Elife, 11(0).
PMID: 35411847
Species: Mouse
Sample Types: Serum

Y Pang et al. (2022), Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection Cell Reports, 39(3):110698.
PMID: 35443182
Species: Mouse
Sample Types: Cell Culture Supernates

RM van Harten et al. (2022), d-enantiomers of CATH-2 enhance the response of macrophages against Streptococcus suis serotype 2 Journal of advanced research, 36(0):101-112.
PMID: 35127168
Species: Mouse
Sample Types: Cell Culture Supernates

S Lee et al. (2022), Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress Cell Death Disease, 2022;13(2):127.
PMID: 35136051
Species: Mouse
Sample Types: Tissue Lysates

AM Dave et al. (2022), Neonatal Hypoxic-Ischemic Brain Injury Alters Brain Acylcarnitine Levels in a Mouse Model Metabolites, 12(5).
PMID: 35629971
Species: Mouse
Sample Types: Cell Culture Supernates

T Huang et al. (2022), Salmonella Enteritidis GalE Protein Inhibits LPS-Induced NLRP3 Inflammasome Activation Microorganisms, 10(5).
PMID: 35630356
Species: Mouse
Sample Types: BALF

A Ulu et al. (2022), IL-22 regulates inflammatory responses to agricultural dust-induced airway inflammation Toxicology and Applied Pharmacology, 0(0):116044.
PMID: 35525330
Species: Mouse
Sample Types: Cell Culture Supernates

Y Zhang et al. (2022), Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage International immunopharmacology, 111(0):109179.
PMID: 36029666
Species: Mouse
Sample Types: Cell Culture Supernates

AL Saraiva et al. (2022), Polyphenols-Rich Fraction from Annona muricata Linn. Leaves Attenuates Oxidative and Inflammatory Responses in Neutrophils, Macrophages, and Experimental Lung Injury Pharmaceutics, 14(6).
PMID: 35745755
Species: Mouse
Sample Types: Tissue Homogenates

AD Kenney et al. (2022), Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis Science Advances, 8(19):eabm5371.
PMID: 35544568
Species: Mouse
Sample Types: Cell Culture Supernates

Y Xu et al. (2022), Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies European Journal of Medicinal Chemistry, 238(0):114468.
PMID: 35635948
Species: Mouse
Sample Types: Serum

S Kim et al. (2022), The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke Redox Biology, 54(0):102347.
PMID: 35688114
Species: Mouse
Sample Types: Serum

SY Park et al. (2022), Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice Journal of Neuroinflammation, 19(1):143.
PMID: 35690816
Species: Mouse
Sample Types: Cell Culture Supernates

V Kim et al. (2022), IL-17-producing follicular Th cells enhance plasma cell differentiation in lupus-prone mice JCI Insight, 7(11).
PMID: 35674135
Species: Mouse
Sample Types: Cell Culture Supernates

AP Young et al. (2022), Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro Brain, Behavior, and Immunity, 105(0):29-43.
PMID: 35764268
Species: Mouse
Sample Types: Tissue Homogenates

S Zhao et al. (2022), Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation Oncogene, 2022(0):1671438.
PMID: 35720180
Species: Mouse
Sample Types: BALF

HOJ Morad et al. (2022), Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release Scientific Reports, 12(1):11078.
PMID: 35773325
Species: Mouse
Sample Types: Tissue Homogenates

H Choe et al. (2022), Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration Oncogene, 43(0):267-276.
PMID: 35678763
Species: Mouse
Sample Types: Cell Lysates

J Liu et al. (2022), Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling Mediators of Inflammation, 2022(0):3441357.
PMID: 36211988
Species: Human
Sample Types: Cell Culture Supernates

SJ Matissek et al. (2022), A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Oncotarget, 13(0):944-959.
PMID: 35937499
Species: Mouse
Sample Types: BALF

W Chen et al. (2022), Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion Nature Immunology, 23(7):1021-1030.
PMID: 35794369
Species: Mouse
Sample Types: Cell Culture Supernates

AE Pottash et al. (2022), Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy Non-coding RNA, 8(5).
PMID: 36287123
Species: Mouse
Sample Types: Serum

PF Kinoshita et al. (2022), Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice Biomedicines, 10(11).
PMID: 36428505
Species: Mouse
Sample Types: Cell Culture Supernates

J Hu et al. (2022), Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling International journal of biological sciences, 18(11):4545-4559.
PMID: 35864954
Species: Mouse
Sample Types: Cell Culture Supernates

PS Woods et al. (2022), HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury Elife, 11(0).
PMID: 35822617
Species: Mouse
Sample Types: Cell Culture Supernates

PS Vieceli et al. (2021), Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms Journal of ethnopharmacology, 0(0):113986.
PMID: 33675915
Species: Mouse
Sample Types: Peritoneal Fluid

M Bambouskov et al. (2021), Itaconate confers tolerance to late NLRP3 inflammasome activation Cell Reports, 34(10):108756.
PMID: 33691097
Species: Mouse
Sample Types: Cell Culture Supernates

P Wohlrab et al. (2021), Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions Physiological Reports, 9(3):e14590.
PMID: 33565273
Species: Mouse
Sample Types: Cell Culture Supernates

JM Hong et al. (2021), Anti-Inflammatory Effects of Antarctic Lichen Umbilicaria antarctica Methanol Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophage Cells and Zebrafish Model BioMed Research International, 2021(0):8812090.
PMID: 33644231
Species: Mouse
Sample Types: Cell Culture Supernates

K Ueno et al. (2021), Cryptococcus gattii evades CD11b-mediated fungal recognition by coating itself with capsular polysaccharides European Journal of Immunology, 0(0).
PMID: 33728652
Species: Mouse
Sample Types: Tissue Homogenates

R Nehmar et al. (2021), Aryl hydrocarbon receptor (Ahr)-dependent Il-22 expression by type 3 innate lymphoid cells control of acute joint inflammation Journal of Cellular and Molecular Medicine, 0(0).
PMID: 33734594
Species: Mouse
Sample Types: Cell Culture Supernates

N Lee et al. (2021), Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways Journal of Immunology Research, 2021(0):9944880.
PMID: 34124273
Species: Mouse
Sample Types: Tissue Homogenates

D Arsenijevi et al. (2021), Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis Nutrients, 13(3).
PMID: 33809904
Species: Mouse
Sample Types: Cell Culture Supernates

JK Dowling et al. (2021), Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages Nature Communications, 12(1):1460.
PMID: 33674584
Species: Mouse
Sample Types: Serum

FR Pinheiro-N et al. (2021), &alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain Toxicology and Applied Pharmacology, 418(0):115497.
PMID: 33744277
Species: Mouse
Sample Types: Serum

SG Jang et al. (2021), Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3 Journal of Translational Medicine, 19(1):86.
PMID: 33632240
Species: Mouse
Sample Types: Cell Culture Supernates

A Chaffey et al. (2021), The Adjuvants Polyphosphazene (PCEP) and a Combination of Curdlan Plus Leptin Promote a Th17-Type Immune Response to an Intramuscular Vaccine in Mice Vaccines, 9(5).
PMID: 34069081
Species: Mouse
Sample Types: Cell Culture Supernates

P Diez-Echav et al. (2021), Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572 Nutrients, 13(6).
PMID: 34072532
Species: Mouse
Sample Types: Cell Culture Supernates

JS Ha et al. (2021), Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis International Journal of Molecular Sciences, 22(3).
PMID: 33530496
Species: Mouse
Sample Types: Cell Culture Supernates

A Amend et al. (2021), Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus International Journal of Molecular Sciences, 22(3).
PMID: 33572870
Species: Mouse
Sample Types: Cell Culture Supernates

KP Foley et al. (2021), Inflammation promotes adipocyte lipolysis via IRE1 kinase The Journal of Biological Chemistry, 0(0):100440.
PMID: 33610548
Species: Mouse
Sample Types: Tissue Homogenates

B Venkataram et al. (2021), Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor Nutrients, 13(4).
PMID: 33920708
Species: Mouse
Sample Types: Cell Culture Supernates

M Najibi et al. (2021), A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS Autophagy, 0(0).
PMID: 33818279
Species: Mouse
Sample Types: Plasma

R Peruzzo et al. (2021), Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction Nature Communications, 12(1):2103.
PMID: 33833234
Species: Mouse
Sample Types: Tissue Homogenates

B Wang et al. (2021), Bifidobacterium adolescentis Isolated from Different Hosts Modifies the Intestinal Microbiota and Displays Differential Metabolic and Immunomodulatory Properties in Mice Fed a High-Fat Diet Nutrients, 13(3).
PMID: 33801119
Species: Mouse
Sample Types: Cell Culture Supernates

B Friedrich et al. (2021), Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release International Journal of Molecular Sciences, 22(8).
PMID: 33923700
Species: Mouse
Sample Types: Cell Culture Supernates

CF Ellefsen et al. (2021), Water-soluble polysaccharides from Pleurotus eryngii fruiting bodies, their activity and affinity for Toll-like receptor 2 and dectin-1 Carbohydrate polymers, 264(0):117991.
PMID: 33910729
Species: Mouse
Sample Types: Serum

C Loira-Past et al. (2021), Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer International journal of pharmaceutics, 600(0):120504.
PMID: 33753161
Species: Mouse
Sample Types: Tissue Homogenates

G Cavalli et al. (2021), The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity Cell Reports, 35(1):108955.
PMID: 33826894
Species: Mouse
Sample Types: BALF

D Shah et al. (2021), Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) International Journal of Molecular Sciences, 22(5).
PMID: 33806560
Species: Mouse
Sample Types: Cell Culture Supernates

J Wu et al. (2021), Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia PLoS ONE, 16(5):e0251677.
PMID: 33984046
Species: Mouse
Sample Types: Cell Culture Supernates

A Doni et al. (2021), Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus Nature Communications, 12(1):3739.
PMID: 34145258
Species: Mouse
Sample Types: Exosomes

LG Lima et al. (2021), Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 12(1):3543.
PMID: 34112803
Species: Mouse
Sample Types: Cell Culture Supernates

EK Robinson et al. (2021), Generation and utilization of a HEK-293T murine GM-CSF expressing cell line PLoS ONE, 16(4):e0249117.
PMID: 33836009
Species: Mouse
Sample Types: Cell Culture Supernates

K Matsushita et al. (2021), The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice JCI Insight, 6(12).
PMID: 34156030
Species: Mouse
Sample Types: Cell Culture Supernates

HJ Shin et al. (2021), Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes Aging Cell, 0(0):e13410.
PMID: 34087956
Species: Mouse
Sample Types: BALF

A Ulu et al. (2021), A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts: Role of DHA in repetitive organic dust exposure The Journal of nutritional biochemistry, 0(0):108797.
PMID: 34126202
Species: Mouse
Sample Types: Cell Culture Supernates

SE Huang et al. (2021), In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis Biomedicines, 9(6).
PMID: 34071594
Species: Mouse
Sample Types: Cell Culture Supernates

DJ Levy et al. (2021), Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host PloS Neglected Tropical Diseases, 15(6):e0009526.
PMID: 34153047
Species: Mouse
Sample Types: Tissue Homogenates

MTP de Oliveir et al. (2021), Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice Pharmaceutics, 13(5).
PMID: 34068619
Species: Mouse
Sample Types: Cell Culture Supernates

JR Santin et al. (2021), Sambucus nigra: A traditional medicine effective in reducing inflammation in mice Journal of ethnopharmacology, 283(0):114736.
PMID: 34648899
Species: Mouse
Sample Types: Cell Culture Supernates

CC Lin et al. (2021), Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Nature Communications, 12(1):3878.
PMID: 34188032
Species: Mouse
Sample Types: Cell Culture Supernates

S Rastogi et al. (2021), Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF PloS Pathogens, 17(7):e1009712.
PMID: 34324582
Species: Mouse
Sample Types: Cell Culture Supernates

L Benvenutti et al. (2021), Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs Journal of Immunology Research, 2021(0):9957451.
PMID: 34337087
Species: Mouse
Sample Types: Cell Culture Supernates

L Liu et al. (2021), DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization Cell Death Disease, 2021;12(6):500.
PMID: 34001860
Species: Mouse
Sample Types: BALF

N Majumder et al. (2021), Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure Redox Biology, 46(0):102092.
PMID: 34418598
Species: Mouse
Sample Types: Cell Culture Supernates

SKH Chow et al. (2021), Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway International Journal of Molecular Sciences, 22(16).
PMID: 34445423
Species: Mouse
Sample Types: Cell Culture Supernates

W Wang et al. (2021), Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release International Journal of Molecular Sciences, 22(16).
PMID: 34445536
Species: Mouse
Sample Types: Cell Culture Supernates

WJ Melvin et al. (2021), Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2 Proceedings of the National Academy of Sciences of the United States of America, 118(38).
PMID: 34479991
Species: Mouse
Sample Types: Tissue Homogenates

SR Bruno et al. (2021), DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 22(20).
PMID: 34681784
Species: Mouse
Sample Types: Cell Culture Supernates

AM Ghanim et al. (2021), Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition European Journal of Medicinal Chemistry, 219(0):113457.
PMID: 33892270
Species: Mouse
Sample Types: Cell Culture Supernates

A Razim et al. (2021), Silicone Oil-Based Nanoadjuvants as Candidates for a New Formulation of Intranasal Vaccines Vaccines, 9(3).
PMID: 33800507
Species: Mouse
Sample Types: Cell Lysates

P Rozier et al. (2021), Lung Fibrosis Is Improved by Extracellular Vesicles from IFNgamma-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis Cells, 10(10).
PMID: 34685707
Species: Mouse
Sample Types: Cell Culture Supernates

S Estfanous et al. (2021), Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo Scientific Reports, 11(1):855.
PMID: 33441602
Species: Mouse
Sample Types: Cell Culture Supernates

J Hu et al. (2021), Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling Cell Reports, 36(12):109726.
PMID: 34551302
Species: Mouse
Sample Types: Plasma

VC Bobbo et al. (2021), Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis Journal of Neuroinflammation, 18(1):192.
PMID: 34465367
Species: Mouse
Sample Types: BALF

N Majumder et al. (2021), Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway Redox Biology, 47(0):102161.
PMID: 34624601
Species: Mouse
Sample Types: Cell Culture Supernates

M Grancieri et al. (2021), Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPAR&gamma and NF-&kappaB Pathways in 3T3L-1 Adipocytes Nutrients, 13(1).
PMID: 33430086
Species: Mouse
Sample Types: Tissue Homogenates

S Droho et al. (2021), Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis Scientific Reports, 11(1):18084.
PMID: 34508129
Species: Mouse
Sample Types: Plasma

S Li et al. (2021), All?trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury Molecular Medicine Reports, 24(6).
PMID: 34676874
Species: Mouse
Sample Types: Tissue Homogenates

WC Chou et al. (2021), AIM2 in regulatory T cells restrains autoimmune diseases Nature, 0(0).
PMID: 33505023
Species: Mouse
Sample Types: Plasma

KC Ngamsri et al. (2021), CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling International Journal of Molecular Sciences, 22(24).
PMID: 34948374
Species: Mouse
Sample Types: Tissue Homogenates

BY Lee et al. (2021), Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis Nature Communications, 12(1):7336.
PMID: 34921158
Species: Mouse
Sample Types: Plasma

P Sun et al. (2021), Hepatocytes are resistant to cell death from canonical and non-canonical inflammasome-activated pyroptosis Cellular and Molecular Gastroenterology and Hepatology, 0(0).
PMID: 34890842
Species: Mouse
Sample Types: Serum

J Tomala et al. (2021), IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells Elife, 10(0).
PMID: 34932467
Species: Mouse
Sample Types: Cell Culture Supernates

J Lücht et al. (2021), Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia Mediators of Inflammation, 2021(0):8906561.
PMID: 34776788
Species: Mouse
Sample Types: Cell Culture Supernates

L Zou et al. (2021), Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis Brain, Behavior, and Immunity, 100(0):10-24.
PMID: 34808293
Species: Mouse
Sample Types: Cell Culture Supernates

MC Kiritsy et al. (2021), Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells Elife, 10(0).
PMID: 34726598
Species: Mouse
Sample Types: Cell Culture Supernates

CM Bobba et al. (2021), Nanoparticle delivery of microRNA-146a regulates mechanotransduction in lung macrophages and mitigates injury during mechanical ventilation Nature Communications, 12(1):289.
PMID: 33436554
Species: Mouse
Sample Types: Cell Culture Supernates

B Dunkhuntho et al. (2021), Gymnema inodorum (Lour.) Decne. Extract Alleviates Oxidative Stress and Inflammatory Mediators Produced by RAW264.7 Macrophages Oxidative Medicine and Cellular Longevity, 2021(0):8658314.
PMID: 33613825
Species: Mouse
Sample Types: Tissue Homogenates

MN Rana et al. (2021), PDE9 Inhibitor PF-04447943 Attenuates DSS-Induced Colitis by Suppressing Oxidative Stress, Inflammation, and Regulating T-Cell Polarization Frontiers in Pharmacology, 12(0):643215.
PMID: 33967779
Species: Mouse
Sample Types: Tissue Homogenates

MG Granja et al. (2021), Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life Journal of Neuroinflammation, 18(1):60.
PMID: 33632243
Species: Mouse
Sample Types: Serum

AV Ferreira et al. (2021), Limited role of the spleen in a mouse model of trained immunity: Impact on neutrophilia Journal of leukocyte biology, 0(0).
PMID: 34596266
Species: Mouse
Sample Types: Cell Culture Supernates

SG Lee et al. (2021), Synergistic inhibitory effects of the oxyresveratrol and dacarbazine combination against melanoma cells Oncology Letters, 22(3):667.
PMID: 34386089
Species: Mouse
Sample Types: Cell Lysates

H Ahn et al. (2021), NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation Cells, 10(7).
PMID: 34359830
Species: Mouse
Sample Types: Tissue Homogenates

Z Ferdous et al. (2021), Remote effects and biodistribution of pulmonary instilled silver nanoparticles in mice NanoImpact, 22(0):100310.
PMID: 35559967
Species: Mouse
Sample Types: cell culture supernatant

Y Lu et al. (2020), The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity Obes Facts, 0(0):1-16.
PMID: 31962332
Species: Mouse
Sample Types: Cell Culture Superantes

CL Hsu et al. (2020), Allergic inflammation is initiated by IL-33-dependent crosstalk between mast cells and basophils PLoS ONE, 15(1):e0226701.
PMID: 31940364
Species: Mouse
Sample Types: Cell Culture Supern

J Cardinal v et al. (2020), Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures Molecules, 25(3).
PMID: 31979350
Species: Mouse
Sample Types: Serum

J Kim et al. (2020), I&kappaB? controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene Cytokine, 127(0):154983.
PMID: 31918161
Species: Mouse
Sample Types: Cell Culture Supernates

HJ Jung et al. (2020), Detrimental Role of Nerve Injury-Induced Protein 1 in Myeloid Cells under Intestinal Inflammatory Conditions Int J Mol Sci, 21(2).
PMID: 31963519
Species: Mouse
Sample Types: Serum

P Saha et al. (2020), Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains Physiol Rep, 8(9):e14441.
PMID: 32385968
Species: Mouse
Sample Types: Cell Culture Supernates

KI Lee et al. (2020), Strain-Specific Differences in House Dust Mite (Dermatophagoides farinae)-Induced Mouse Models of Allergic Rhinitis Clin Exp Otorhinolaryngol, 0(0).
PMID: 32407614
Species: Mouse
Sample Types: Cell Culture Supernates

K Tamminen et al. (2020), Rotavirus VP6 Adjuvant Effect on Norovirus GII.4 Virus-Like Particle Uptake and Presentation by Bone Marrow-Derived Dendritic Cells In Vitro and In Vivo J Immunol Res, 2020(0):3194704.
PMID: 32411793
Species: Mouse
Sample Types: Serum

M Mohammad et al. (2020), The role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis Sci Rep, 10(1):7936.
PMID: 32404866
Species: Mouse
Sample Types: Cell Culture Supernates

K Pacyga et al. (2020), The Bioinformatic and In Vitro Studies of Clostridioides Difficile Aminopeptidase M24 Revealed the Immunoreactive KKGIK Peptide Cells, 9(5).
PMID: 32392707
Species: Mouse
Sample Types: Cell Culture Supernates

HC Lin et al. (2020), M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides Evid Based Complement Alternat Med, 2020(0):9450246.
PMID: 32308723
Species: Mouse
Sample Types: Cell Culture Supernates

LRC de Oliveir et al. (2020), Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation Front Pharmacol, 11(0):161.
PMID: 32226379
Species: Mouse
Sample Types: Cell Culture Supernates

KA Sun et al. (2020), Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response Elife, 9(0).
PMID: 32255424
Species: Mouse
Sample Types: Cell Culture Supernates

KW Kim et al. (2020), FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress Cell Death Dis, 11(4):285.
PMID: 32332708
Species: Mouse
Sample Types: Cell Culture Supernates

RDC da Cunha d et al. (2020), Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity Physiol Rep, 8(4):e14380.
PMID: 32109344
Species: Mouse
Sample Types: Cell Culture Supernates

Y Guo et al. (2020), Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation BMC Microbiol., 20(1):226.
PMID: 32723297
Species: Mouse
Sample Types: Serum

J Varghese et al. (2020), Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet J. Nutr. Biochem., 84(0):108441.
PMID: 32629238
Species: Mouse
Sample Types: Serum

A Jarneborn et al. (2020), Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice Sci Rep, 10(1):10891.
PMID: 32616791
Species: Human
Sample Types: Cell Culture Supernates

M Sermershei et al. (2020), MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling Nat Commun, 11(1):3624.
PMID: 32681036
Species: Mouse
Sample Types: Cell Lysates

JJ Balic et al. (2020), STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression Nat Commun, 11(1):3816.
PMID: 32732870
Species: Mouse
Sample Types: Tissue Homogenates

A Nemmar et al. (2020), Nose-Only Water-Pipe Smoke Exposure in Mice Elicits Renal Histopathological Alterations, Inflammation, Oxidative Stress, DNA Damage, and Apoptosis Front Physiol, 11(0):46.
PMID: 32116758
Species: Mouse
Sample Types: CSF

S Teruya et al. (2020), Bordetella Dermonecrotic Toxin Is a Neurotropic Virulence Factor That Uses CaV3.1 as the Cell Surface Receptor MBio, 11(2).
PMID: 32209694
Species: Mouse
Sample Types: Serum

R Li et al. (2020), Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models Nat Commun, 11(1):642.
PMID: 32005799
Species: Mouse
Sample Types: Cell Culture Supernates

E Gimier et al. (2020), Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn's disease Sci Rep, 10(1):12922.
PMID: 32737335
Species: Mouse
Sample Types: Cell Culture Supernates

S Lee et al. (2020), The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response J Neuroinflammation, 17(1):299.
PMID: 33054766
Species: Mouse
Sample Types: Cell Culture Supernates

YS Lee et al. (2020), Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice BMC Complement Med Ther, 20(1):270.
PMID: 32894124
Species: Mouse
Sample Types: Cell Lysates

SJ Jeong et al. (2020), Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm Exp. Mol. Med., 0(0).
PMID: 32929220
Species: Mouse
Sample Types: Cell Culture Supernates

P De Cicco et al. (2020), Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization Nutrients, 12(12).
PMID: 33260769
Species: Mouse
Sample Types: Cell Lysates

JM Kline et al. (2020), Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice PLoS ONE, 15(10):e0241218.
PMID: 33104726
Species: Mouse
Sample Types: Plasma

A Taberner-C et al. (2020), Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance International Journal of Molecular Sciences, 21(23).
PMID: 33287201
Species: Mouse
Sample Types: Cell Culture Supernates

XAMH van Dieren et al. (2020), The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance J Biol Chem, 0(0).
PMID: 33051201
Species: Mouse
Sample Types: Cell Culture Supernates

JC DuBois et al. (2020), Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis J Neuroinflammation, 17(1):324.
PMID: 33121494
Species: Mouse
Sample Types: BALF

R Li et al. (2020), Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury Molecular Medicine Reports, 0(0).
PMID: 32945411
Species: Mouse
Sample Types: Tissue Homogenates

M Hernández et al. (2020), Dual chemotherapy with benznidazole at suboptimal dose plus curcumin nanoparticles mitigates Trypanosoma cruzi-elicited chronic cardiomyopathy Parasitol Int, 81(0):102248.
PMID: 33238215
Species: Mouse
Sample Types: Tissue Homogenates

MC Gestal et al. (2020), Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract Microorganisms, 8(11).
PMID: 33212993
Species: Mouse
Sample Types: Cell Culture Supernates

FM de Jesus O et al. (2020), Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis Mediators Inflamm, 2020(0):1839762.
PMID: 33110395
Species: Mouse
Sample Types: Plasma

B Relja et al. (2020), Different experimental multiple trauma models induce comparable inflammation and organ injury Sci Rep, 10(1):20185.
PMID: 33214576
Species: Mouse
Sample Types: Cell Culture Supernates

DM de Graaf et al. (2020), Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease Cytokine, 137(0):155334.
PMID: 33128926
Species: Mouse
Sample Types: Tissue Homogenates

LEF Silva et al. (2020), Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins Scientific Reports, 10(1):15287.
PMID: 32943702
Species: Mouse
Sample Types: Cell Culture Supernates

A Fajstova et al. (2020), Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling Cells, 9(12).
PMID: 33339337
Species: Mouse
Sample Types: Serum

DO Kim et al. (2020), TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection International Journal of Molecular Sciences, 21(24).
PMID: 33327533
Species: Mouse
Sample Types: Serum

N Ito et al. (2020), Neuroinflammaging underlies emotional disturbances and circadian rhythm disruption in young male senescence-accelerated mouse prone 8 mice Exp Gerontol, 0(0):111109.
PMID: 33069781
Species: Mouse
Sample Types: Cell Culture Supernates

S Saito et al. (2020), Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice Nutrients, 12(11).
PMID: 33121026
Species: Mouse
Sample Types: Cell Culture Supernates

J Sun et al. (2020), The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta EBioMedicine, 60(0):102984.
PMID: 32979835
Species: Mouse
Sample Types: Cell Culture Supernates

F Yang et al. (2020), Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice Drug Des Devel Ther, 14(0):3865-3874.
PMID: 33061293
Species: Mouse
Sample Types: Cell Cultue Supernates

XAMH van Dieren et al. (2020), HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation Cell Rep, 30(6):1811-1822.e6.
PMID: 32049012
Species: Mouse
Sample Types: Tissue Homogenates

H Ma et al. (2020), Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation Cell Rep, 30(3):793-806.e6.
PMID: 31968254
Species: Mouse
Sample Types: Tissue Culture Supernates

O Dusek et al. (2020), Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917 Cells, 10(1).
PMID: 33375578
Species: Mouse
Sample Types: Cell Culture Supernates

B Dunkhuntho et al. (2020), Intracellular ROS Scavenging and Anti-Inflammatory Activities of Oroxylum indicum Kurz (L.) Extract in LPS plus IFN-gamma-Activated RAW264.7 Macrophages Evid Based Complement Alternat Med, 2020(0):7436920.
PMID: 32565874
Species: Mouse
Sample Types: Serum

T Sakaguchi et al. (2020), TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes Cell Rep, 31(10):107755.
PMID: 32521253
Species: Mouse
Sample Types: Serum

J Wu et al. (2020), Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion Sci Adv, 6(24):eaba3458.
PMID: 32582853
Species: Mouse
Sample Types: Cell Culture Supernates

SS Chiang et al. (2020), Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function Chemosphere, 267(0):129267.
PMID: 33338714
Species: Mouse
Sample Types: Serum

B Cuffaro et al. (2020), In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice Cells, 9(9).
PMID: 32947881
Species: Mouse
Sample Types: Tissue Homogenates

DC Badgujar et al. (2020), Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle PloS Pathogens, 16(11):e1009016.
PMID: 33216805
Species: Mouse
Sample Types: Serum

X Li et al. (2020), Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners Nature Communications, 11(1):6364.
PMID: 33311474
Species: Mouse
Sample Types: BALF

F Botelho et al. (2020), IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M Mediators of Inflammation, 2020(0):4087315.
PMID: 33376451
Species: Mouse
Sample Types: Tissue Homogenates

A Nemmar et al. (2020), Comparative Study on Pulmonary Toxicity in Mice Induced by Exposure to Unflavoured and Apple- and Strawberry-Flavoured Tobacco Waterpipe Smoke Oxid Med Cell Longev, 2020(0):6450450.
PMID: 32025277
Species: Mouse
Sample Types: Cell Culture Supernates

PM Jordan et al. (2020), Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution Cell Rep, 33(2):108247.
PMID: 33053344
Species: Mouse
Sample Types: Cell Culture Supernates

M Passariell et al. (2020), Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells Cancers (Basel), 12(8).
PMID: 32781690
Species: Mouse
Sample Types: Tissue Homogenates

E Gimier et al. (2020), Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn's disease Sci Rep, 10(1):12922.
PMID: 32737335
Species: Mouse
Sample Types: Serum

H Cui et al. (2019), Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 0(0).
PMID: 30676324
Species: Mouse
Sample Types: Serum

JH Nho et al. (2019), Effect of Saururus chinensis leaves extract on type II collagen-induced arthritis mouse model BMC Complement Altern Med, 19(1):2.
PMID: 30606189
Species: Mouse
Sample Types: Serum

LE Hand et al. (2019), The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis Arthritis Res. Ther., 21(1):5.
PMID: 30612576
Species: Mouse
Sample Types: Serum

JH Nho et al. (2019), Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice Evid Based Complement Alternat Med, 2019(0):3637453.
PMID: 30713571
Species: Mouse
Sample Types: Cell Culture Supernates

N Pacienza et al. (2019), Inï¿½Vitro Macrophage Assay Predicts the Inï¿½Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells Mol Ther Methods Clin Dev, 13(0):67-76.
PMID: 30719485
Species: Mouse
Sample Types: Cell Culture Supernates

F Zahedifard et al. (2019), Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials PLoS Negl Trop Dis, 13(2):e0007217.
PMID: 30811391
Species: Mouse
Sample Types: Serum

DC Arruda et al. (2019), Modifying internal organization and surface morphology of siRNA lipoplexes by sodium alginate addition for efficient siRNA delivery J Colloid Interface Sci, 540(0):342-353.
PMID: 30660791
Species: Mouse
Sample Types: Cell Culture Supernates

AC Luissint et al. (2019), Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice Mucosal Immunol, 0(0).
PMID: 30745566
Species: Mouse
Sample Types: Cell Culture Supernates

EZ Eisenmesse et al. (2019), Interleukin-37 monomer is the active form for reducing innate immunity Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30819901
Species: Mouse
Sample Types: Wound Lavage Fluid

L Oezel et al. (2019), Effect of antibiotic infused calcium sulfate/hydroxyapatite (CAS/HA) insets on implant-associated osteitis in a femur fracture model in mice PLoS ONE, 14(3):e0213590.
PMID: 30870491
Species: Mouse
Sample Types: Tissue Homogenates

TA Diniz et al. (2019), Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice Cytokine, 119(0):71-80.
PMID: 30903866
Species: Mouse
Sample Types: Cell Culture Supernates

G Thomi et al. (2019), Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury Stem Cell Res Ther, 10(1):105.
PMID: 30898154
Species: Mouse
Sample Types: Cell Culture Supernates

OM Finucane et al. (2019), The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages Sci Rep, 9(1):4034.
PMID: 30858427
Species: Mouse
Sample Types: Tissue Homogenates

Z Gong et al. (2019), Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice J Neuroinflammation, 16(1):62.
PMID: 30871577
Species: Mouse
Sample Types: Serum

F Ascenzi et al. (2019), Effects of IGF-1 isoforms on muscle growth and sarcopenia Aging Cell, 0(0):e12954.
PMID: 30953403
Species: Mouse
Sample Types: Cell Culture Supernates

V Koliaraki et al. (2019), Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis Cell Rep, 26(3):536-545.e4.
PMID: 30650348
Species: Mouse
Sample Types: Serum

J Aguilera-H et al. (2019), A Live Salmonella Vaccine Delivering PcrV through the Type III Secretion System Protects against Pseudomonas aeruginosa mSphere, 4(2).
PMID: 30996108
Species: Mouse
Sample Types: Cell Culture Supernates

Z Moosova et al. (2019), Immunomodulatory effects of cyanobacterial toxin cylindrospermopsin on innate immune cells Chemosphere, 226(0):439-446.
PMID: 30951938
Species: Mouse
Sample Types: Tissue Homogenates

AML Scantleber et al. (2019), NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin PLoS ONE, 14(3):e0214437.
PMID: 30908533
Species: Mouse
Sample Types: Cell Culture Supernates

DDP Putri et al. (2019), PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking J. Biol. Chem., 0(0).
PMID: 30944173
Species: Mouse
Sample Types: Cell Culture Supernates

VB Lê et al. (2019), Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice PLoS Pathog., 15(4):e1007689.
PMID: 30964929
Species: Mouse
Sample Types: Tissue Homogenates

JL Fachi et al. (2019), Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism Cell Rep, 27(3):750-761.e7.
PMID: 30995474
Species: Mouse
Sample Types: Plasma

VN Camargos et al. (2019), In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy EBioMedicine, 0(0).
PMID: 31130472
Species: Mouse
Sample Types: Tissue Homogenates

EM Nakada et al. (2019), Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers JCI Insight, 4(9).
PMID: 31045581
Species: Mouse
Sample Types: Tissue Homogenates

BVS Valiate et al. (2019), The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice J. Leukoc. Biol., 0(0).
PMID: 31107994
Species: Mouse
Sample Types: Cell Culture Supernates

I Santecchia et al. (2019), Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection PLoS Pathog., 15(5):e1007811.
PMID: 31107928
Species: Mouse
Sample Types: Plasma

T Tominaga et al. (2019), Glucose Ingestion Inhibits Endurance Exercise-Induced IL-6 Producing Macrophage Infiltration in Mice Muscle Nutrients, 11(7).
PMID: 31262006
Species: Mouse
Sample Types: BALF

JQ Yang et al. (2019), Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation J. Leukoc. Biol., 0(0).
PMID: 31260596
Species: Mouse
Sample Types: Cell Culture Supernates

L Yue et al. (2019), PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils PLoS ONE, 14(9):e0222753.
PMID: 31532798
Species: Mouse
Sample Types: Cell Culture Supernates

I Chiulan et al. (2019), Comprehensive characterization of silica-modified silicon rubbers J Mech Behav Biomed Mater, 101(0):103427.
PMID: 31539735
Species: Mouse
Sample Types: Plasma

S Tariket et al. (2019), Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury Sci Rep, 9(1):12536.
PMID: 31467410
Species: Mouse
Sample Types: Tissue Lysates

TDSM Farias et al. (2019), Melatonin Supplementation Attenuates the Pro-Inflammatory Adipokines Expression in Visceral Fat from Obese Mice Induced by A High-Fat Diet Cells, 8(9).
PMID: 31489938
Species: Mouse
Sample Types: Tissue Homogenates

DR Lacerda et al. (2019), Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice J. Nutr. Biochem., 72(0):108208.
PMID: 31473506
Species: Mouse
Sample Types: Cell Culture Supernates

J Periselner et al. (2019), Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae MBio, 10(5).
PMID: 31551336
Species: Mouse
Sample Types: Tissue Homogenates

Y Lin et al. (2019), Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis Mucosal Immunol, 0(0).
PMID: 31534167
Species: Mouse
Sample Types: Cell Culture Supernates

O Danov et al. (2019), Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo Respir. Res., 20(1):228.
PMID: 31640701
Species: Mouse
Sample Types: Cell Culture Supernates

Y Song et al. (2019), Enzyme Treatment Alters the Anti-Inflammatory Activity of the Water Extract of Wheat Germ In Vitro and In Vivo Nutrients, 11(10).
PMID: 31623257
Species: Mouse
Sample Types: BALF

E Morello et al. (2019), Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling Front Microbiol, 10(0):1826.
PMID: 31474948
Species: Mouse
Sample Types: Cell Culture Supernates

CL Sanchez et al. (2019), Endoplasmic reticulum stress differentially modulates the IL-6 family of cytokines in murine astrocytes and macrophages Sci Rep, 9(1):14931.
PMID: 31624329
Species: Mouse
Sample Types: Peritoneal Lavage Fluid

A Rahman et al. (2019), Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation Elife, 8(0).
PMID: 31613219
Species: Mouse
Sample Types: Tissue Lysates

H Huang et al. (2019), Targeting TGFbetaR2-mutant tumors exposes vulnerabilities to stromal TGFbeta blockade in pancreatic cancer EMBO Mol Med, 0(0):e10515.
PMID: 31609088
Species: Mouse
Sample Types: Cell Culture Supernates

L Ji et al. (2019), Roxatidine inhibits fibrosis by inhibiting NF?kappaB and MAPK signaling in macrophages sensing breast implant surface materials Mol Med Rep, 0(0).
PMID: 31746427
Species: Mouse
Sample Types: Cell Culture Supernates

NE Powers et al. (2019), PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis J. Biol. Chem., 0(0).
PMID: 31819009
Species: Mouse
Sample Types: Cell Culture Supernates

A Yu et al. (2019), Mucoadhesive dexamethasone-glycol chitosan nanoparticles for ophthalmic drug delivery Int J Pharm, 575(0):118943.
PMID: 31830575
Species: Mouse
Sample Types: Tissue Homogenates

CH Val et al. (2019), SOCS2 modulates adipose tissue inflammation and expansion in mice J. Nutr. Biochem., 76(0):108304.
PMID: 31816561
Species: Mouse
Sample Types: Serum

HQ Tran et al. (2019), Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases Nat Commun, 10(1):5650.
PMID: 31827095
Species: Mouse
Sample Types: Serum

T Jin et al. (2019), A novel mouse model for septic arthritis induced by Pseudomonas aeruginosa Sci Rep, 9(1):16868.
PMID: 31727989
Species: Mouse
Sample Types: Cell Culture Supernates

MJR Ruigrok et al. (2019), The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices Sci Rep, 9(1):16239.
PMID: 31700101
Species: Mouse
Sample Types: Cell culture supernat

A Gebhardt et al. (2019), The alternative cap-binding complex is required for antiviral defense in vivo PLoS Pathog., 15(12):e1008155.
PMID: 31856218
Species: Mouse
Sample Types: Cell Culture Supernates

H Lee et al. (2019), Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet Int J Mol Sci, 20(22).
PMID: 31731705
Species: Mouse
Sample Types: Cell Culture Supernates

VS Tapia et al. (2019), The three cytokines IL-1?, IL-18, and IL-1? share related but distinct secretory routes J. Biol. Chem., 294(21):8325-8335.
PMID: 30940725
Species: Mouse
Sample Types: Tissue Homogenates

M Mohammad et al. (2019), The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus PLoS Pathog., 15(6):e1007877.
PMID: 31226163
Species: Mouse
Sample Types: Tissue Homogenates

B Burger et al. (2019), Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice Sci Rep, 9(1):9119.
PMID: 31235718
Species: Mouse
Sample Types: Cell Culture Supernates

JD Bailey et al. (2019), Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation Cell Rep, 28(1):218-230.e7.
PMID: 31269442
Species: Mouse
Sample Types: Tissue Homogenates

AL Frisbee et al. (2019), IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection Nat Commun, 10(1):2712.
PMID: 31221971
Species: Mouse
Sample Types: Cell Culture Supernates

M Murase et al. (2018), Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking J. Immunol., 0(0).
PMID: 29540576
Species: Mouse
Sample Types: BALF

S Hoegl et al. (2018), Capturing the multifactorial nature of ARDS - "Two-hit" approach to model murine acute lung injury Physiol Rep, 6(6):e13648.
PMID: 29595879
Species: Mouse
Sample Types: Cell Culture Supernates

RG Carroll et al. (2018), An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation J. Biol. Chem., 293(15):5509-5521.
PMID: 29463677
Species: Mouse
Sample Types: Cell Culture Supernates

JM Ludwig et al. (2018), Anti-inflammatory properties of ursodeoxycholyl lysophosphatidylethanolamide in endotoxin-mediated inflammatory liver injury PLoS ONE, 13(5):e0197836.
PMID: 29795632
Species: Mouse
Sample Types: Whole Blood

JB Herrmann et al. (2018), Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.ï¿½meningitidis Sepsis and Is a Potential Target for Disease Treatment MBio, 9(1).
PMID: 29362231
Species: Mouse
Sample Types: BALF

A Sagiv et al. (2018), p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence Cell Rep, 22(13):3468-3479.
PMID: 29590616
Species: Mouse
Sample Types: Tissue Homogenates

JC d'Avila et al. (2018), Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation J Neuroinflammation, 15(1):28.
PMID: 29382344
Species: Mouse
Sample Types: Tissue Homogenates

C Delyea et al. (2018), CD71+ Erythroid Suppressor Cells Promote Fetomaternal Tolerance through Arginase-2 and PDL-1 J. Immunol., 0(0).
PMID: 29735482
Species: Mouse
Sample Types: Cell Culture Supernates

SA Snider et al. (2018), Choline transport links macrophage phospholipid metabolism and inflammation J. Biol. Chem., 0(0).
PMID: 29880645
Species: Mouse
Sample Types: Serum

V Lamontain et al. (2018), Stimulation of TNF receptor type 2 expands regulatory T cells and ameliorates established collagen-induced arthritis in mice Cell. Mol. Immunol., 0(0).
PMID: 29375132
Species: Mouse
Sample Types: Serum

B Chang et al. (2018), Activation of macrophage mediated host defense againstSalmonella typhimuriumbyMorus albaL Food Nutr Res, 62(0).
PMID: 29545736
Species: Mouse
Sample Types: BALF

Y Hayama et al. (2018), Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB J. Immunol., 0(0).
PMID: 29686050
Species: Mouse
Sample Types: Cell Culture Supernates

P Zarin et al. (2018), Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse ?? T Cell Effector Differentiation Immunol. Cell Biol., 0(0).
PMID: 29754419
Species: Mouse
Sample Types: BALF

S Kim et al. (2018), Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia J. Leukoc. Biol., 0(0).
PMID: 29924419
Species: Mouse
Sample Types: Cell Culture Supernates

K Ren et al. (2018), Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation Cell. Physiol. Biochem., 47(5):2170-2184.
PMID: 29975943
Species: Mouse
Sample Types: Cell Culture Supernates

M Blank et al. (2018), Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis PLoS ONE, 13(8):e0200615.
PMID: 30089122
Species: Mouse
Sample Types: BALF

S Cicko et al. (2018), Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI) Oncotarget, 9(55):30635-30648.
PMID: 30093975
Species: Mouse
Sample Types: Cell Culture Supernates

S Offenbache et al. (2018), GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation Nat Commun, 9(1):3686.
PMID: 30206230
Species: Mouse
Sample Types: Plasma

M Imbrechts et al. (2018), Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis J. Immunol., 0(0).
PMID: 30266771
Species: Mouse
Sample Types: Plasma

F Fattahi et al. (2018), Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis Biomed Res Int, 2018(0):4302726.
PMID: 30364002
Species: Mouse
Sample Types: Cell Culture Supernates

D Philipp et al. (2018), Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization Stem Cell Res Ther, 9(1):286.
PMID: 30359316
Species: Mouse
Sample Types: Tissue Homogenates

S Al-Salam et al. (2018), Myocardial Ischemia Reperfusion Injury: Apoptotic, Inflammatory and Oxidative Stress Role of Galectin-3 Cell. Physiol. Biochem., 50(3):1123-1139.
PMID: 30355930
Species: Mouse
Sample Types: Tissue Homogenates

N Eissa et al. (2018), The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism Sci Rep, 8(1):13077.
PMID: 30166610
Species: Mouse
Sample Types: Cell Culture Supernates

M Bambouskov et al. (2018), Electrophilic properties of itaconate and derivatives regulate theï¿½I?B?-ATF3 inflammatory axis Nature, 556(7702):501-504.
PMID: 29670287
Species: Mouse
Sample Types: Cell Culture Supernates

M Obaid et al. (2018), LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages Sci Rep, 8(1):15670.
PMID: 30353135
Species: Mouse
Sample Types: Tissue Homogenates

X Xiao et al. (2018), Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects J. Nutr. Biochem., 62(0):28-34.
PMID: 30218980
Species: Mouse
Sample Types: Cell Culture Supernates

F Sato-Kanek et al. (2018), Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy Biomed Res Int, 2018(0):8091283.
PMID: 30406141
Species: Mouse
Sample Types: Cell Culture Supernates

P Wohlrab et al. (2018), Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells Front Physiol, 9(0):1754.
PMID: 30574096
Species: Mouse
Sample Types: Plasma

AS Meena et al. (2018), EGF receptor plays a role in the mechanism of glutamine-mediated prevention of alcohol-induced gut barrier dysfunction and liver injury J. Nutr. Biochem., 64(0):128-143.
PMID: 30502657
Species: Mouse
Sample Types: BALF

TM Nordgren et al. (2018), Bovine milk-derived extracellular vesicles enhance inflammation and promote M1 polarization following agricultural dust exposure in mice J. Nutr. Biochem., 64(0):110-120.
PMID: 30476878
Species: Mouse
Sample Types: Serum

KME Andersson et al. (2018), Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis Proc. Natl. Acad. Sci. U.S.A., 0(0).
PMID: 30509997
Species: Mouse
Sample Types: Plasma

PK Shukla et al. (2018), Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine Sci Rep, 8(1):16241.
PMID: 30389960
Species: Mouse
Sample Types: Cell Culture Supernates

SR Scutts et al. (2018), DNA-PK Is Targeted by Multiple Vaccinia Virus Proteins to Inhibit DNA Sensing Cell Rep, 25(7):1953-1965.e4.
PMID: 30428360
Species: Mouse
Sample Types: Tissue Homogenates

A de Araújo et al. (2018), Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation Oxid Med Cell Longev, 2018(0):8194849.
PMID: 30647816
Species: Mouse
Sample Types: Cell Culture Supernates

L Subedi et al. (2018), Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway Oxid Med Cell Longev, 2018(0):8092713.
PMID: 30622674
Species: Mouse
Sample Types: Tissue Homogenates

GR Romualdo et al. (2018), Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models PLoS ONE, 13(9):e0203879.
PMID: 30212575
Species: Mouse
Sample Types: Cell Culture Supernates

C Wang et al. (2018), A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence Autophagy, 0(0).
PMID: 30335568
Species: Mouse
Sample Types: Cell Culture Supernates

L Boutens et al. (2018), Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses Diabetologia, 0(0).
PMID: 29333574
Species: Mouse
Sample Types: Cell Culture Supernates

DJ Sharkey et al. (2018), Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 0(0).
PMID: 29596569
Species: Mouse
Sample Types: Serum

D Gr?evi? et al. (2018), The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair Front Immunol, 9(0):417.
PMID: 29556234
Species: Mouse
Sample Types: Cell Culture Supernates

MJ Oh et al. (2018), Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system Biochem. Biophys. Res. Commun., 0(0).
PMID: 29402410
Species: Mouse
Sample Types: Nasal Lavage Fluid

M Ma et al. (2018), Alternaria alternata challenge at the nasal mucosa results in eosinophilic inflammation and increased susceptibility to influenza virus infection Clin. Exp. Allergy, 0(0).
PMID: 29473965
Species: Mouse
Sample Types: Cell Culture Supernates

A Rutkowska et al. (2018), EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes Neuropharmacology, 133(0):121-128.
PMID: 29374507
Species: Mouse
Sample Types: Cell Culture Supernates

F Mouton-Lig et al. (2018), Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop Glia, 0(0).
PMID: 29665074
Species: Mouse
Sample Types: Tissue Homogenates

IK Sundar et al. (2018), Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema FASEB J., 0(0):fj201701518R.
PMID: 29630406
Species: Mouse
Sample Types: Serum

MC Souza et al. (2017), Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis Front Cell Infect Microbiol, 7(0):116.
PMID: 28439500
Species: Mouse
Sample Types: Cell Culture Supernates

K Doiron et al. (2017), The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity Sci Rep, 7(1):107.
PMID: 28273895
Species: Mouse
Sample Types: Cell Culture Supernates

M Lynch et al. (2017), Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response BMC Evol. Biol, 17(1):90.
PMID: 28335725
Species: Mouse
Sample Types: Tissue Homogenates

A Nemmar et al. (2017), Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice Oxid Med Cell Longev, 2017(0):9639035.
PMID: 28392888
Species: Mouse
Sample Types: Cell Culture Supernates

RF Espírito-S et al. (2017), The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches PLoS ONE, 12(6):e0179174.
PMID: 28594906
Species: Mouse
Sample Types: Cell Culture Supernates

KM Schneider et al. (2017), The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages Cytokine, 0(0).
PMID: 28800924
Species: Mouse
Sample Types: Tissue Homogenates

JC Klein et al. (2017), Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth Nat Commun, 8(0):14600.
PMID: 28300057
Species: Mouse
Sample Types: Cell Culture Supernates

JP Barrett et al. (2017), NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury J Neuroinflammation, 14(1):65.
PMID: 28340575
Species: Mouse
Sample Types: Cell Culture Supernates

HH Lee et al. (2017), p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-?B and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages Biol. Pharm. Bull., 40(11):1894-1902.
PMID: 29093336
Species: Mouse
Sample Types: BALF

E Smyth et al. (2017), Influence of inflammation and nitric oxide upon platelet aggregation following deposition of diesel exhaust particles in the airways Br. J. Pharmacol., 0(0).
PMID: 28437857
Species: Mouse
Sample Types: NLF

PC Chen et al. (2017), Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen-induced allergic rhinitis J. Allergy Clin. Immunol., 0(0).
PMID: 28412394
Species: Mouse
Sample Types: Plasma

A Nemmar et al. (2017), Water-Pipe Smoke Exposure-Induced Circulatory Disturbances in Mice, and the Influence of Betaine Supplementation Thereon Cell. Physiol. Biochem, 41(3):1098-1112.
PMID: 28245471
Species: Mouse
Sample Types: Serum

Y Zhou et al. (2017), CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice J. Immunol, 0(0).
PMID: 28219888
Species: Mouse
Sample Types: Tissue Homogenates

J Tode et al. (2017), Intravitreal injection of anti-Interleukin (IL)-6 antibody attenuates experimental autoimmune uveitis in mice Cytokine, 96(0):8-15.
PMID: 28267649
Species: Mouse
Sample Types: Cell Culture Supernates

MJD Daniels et al. (2017), CRISPR/Cas9 mediated mutation of mouse IL-1? nuclear localisation sequence abolishes expression Sci Rep, 7(1):17077.
PMID: 29213066
Species: Mouse
Sample Types: Cell Culture Supernates

HS Han et al. (2017), Kyungheechunggan-Tang-01, a New Herbal Medication, Suppresses LPS-Induced Inflammatory Responses through JAK/STAT Signaling Pathway in RAW 264.7 Macrophages Evid Based Complement Alternat Med, 2017(0):7383104.
PMID: 29348772
Species: Mouse
Sample Types: Cell Culture Supernates

SY Lin et al. (2017), Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance Autophagy, 0(0):0.
PMID: 29171784
Species: Mouse
Sample Types: Cell Culture Supernates

A Imai et al. (2017), Inducing maternal inflammation promotes leptin production in offspring but does not improve allergic symptoms in a mouse model of allergic rhinitis Heliyon, 3(6):e00327.
PMID: 28707000
Species: Mouse
Sample Types: Cell Culture Supernates

H Talwar et al. (2017), The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages Data Brief, 14(0):56-61.
PMID: 28765831
Sample Types: Complex Sample Type

SA O'Sullivan et al. (2017), Demyelination induced by oxidative stress is regulated by sphingosine 1-phosphate receptors Glia, 0(0).
PMID: 28375547
Species: Mouse
Sample Types: Cell Culture Supernates

L Shmuel-Gal et al. (2017), Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration J. Biol. Chem., 0(0).
PMID: 28655763
Species: Mouse
Sample Types: Tissue Homogenates

LN Masi et al. (2017), Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice Sci Rep, 7(1):3937.
PMID: 28638152
Species: Mouse
Sample Types: Cell Culture Supernates

M Coorens et al. (2017), Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner J. Immunol., 0(0).
PMID: 28710255
Species: Mouse
Sample Types: Cell Culture Supernates

TH Tu et al. (2017), Visfatin Triggers Anorexia and Body Weight Loss through Regulating the Inflammatory Response in the Hypothalamic Microglia Mediators Inflamm., 2017(0):1958947.
PMID: 29362519
Species: Mouse
Sample Types: Tissue Homogenates

M Na et al. (2017), Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice PLoS ONE, 12(3):e0173492.
PMID: 28264025
Species: Mouse
Sample Types: Cell Culture Supernates

CF Chang et al. (2017), 2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-?B Pathways in RAW 264.7 Macrophage Cells PLoS ONE, 12(1):e0168945.
PMID: 28060845
Species: Mouse
Sample Types: Tissue Homogenates

BX Ross et al. (2017), IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas J. Immunol, 0(0).
PMID: 28330899
Species: Mouse
Sample Types: BALF

GJ Martínez-C et al. (2017), Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury Mucosal Immunol, 0(0).
PMID: 28589946
Species: Mouse
Sample Types: Plasma

Á Vinué et al. (2017), The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype Diabetologia, 0(0).
PMID: 28608285
Species: Mouse
Sample Types: Cell Culture Supernates

P Marona et al. (2017), MCPIP1 downregulation in clear cell renal cell carcinoma promotes vascularization and metastatic progression Cancer Res., 0(0).
PMID: 28716897
Species: Gerbil
Sample Types: Tissue Homogenates

LL Ventura et al. (2017), Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus) PeerJ, 5(0):e2967.
PMID: 28265495
Species: Mouse
Sample Types: Cell Culture Supernates

FN Penas et al. (2017), Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice Front Immunol, 8(0):1738.
PMID: 29312293
Species: Mouse
Sample Types: BALF

MS Gresnigt et al. (2017), The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression Front Immunol, 8(0):1777.
PMID: 29326692
Species: Mouse
Sample Types: Tissue Homogenates

LB Martins et al. (2017), Paradoxical role of tumor necrosis factor on metabolic dysfunction and adipose tissue expansion in mice Nutrition, 50(0):1-7.
PMID: 29510322
Species: Mouse
Sample Types: BALF

Eun-Jeong Yoon (2016), Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii MBio, 7(3).
PMID: 27247231
Species: Mouse
Sample Types: Cell Culture Supernates

Miguel Del Campo (2016), Sublethal doses of Dinophysistoxin-1 and Okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences Toxicon, 0(0).
PMID: 27956244
Species: Human
Sample Types: Cell Culture Supernates

(2016), Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 6(0):29712.
PMID: 27431276
Species: Mouse
Sample Types: Tissue Homogenates

Silvana Peterini Boeira (2016), Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice Chem. Biol. Interact., 0(0).
PMID: 27818124
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Cannabinoid receptor 2 modulates susceptibility to experimental cerebral malaria through a CCL17-dependent mechanism J Biol Chem, 0(0).
PMID: 27474745
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response Mucosal Immunol, 0(0).
PMID: 27924821
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages J Immunol, 196(11):4650-62.
PMID: 27183578
Species: Mouse
Sample Types: Serum

(2016), Poly-N-acetyl glucosamine production by Staphylococcus epidermidis cells increases their in vivo pro-inflammatory effect Infect Immun, 0(0).
PMID: 27481237
Species: Mouse
Sample Types: Tissue Homogenates

A Savers et al. (2016), Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge PLoS ONE, 11(4):e0153829.
PMID: 27078879
Species: Mouse
Sample Types: Cell Culture Supernates

OB Corneth et al. (2016), Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice Eur J Immunol, 0(0).
PMID: 27067635
Species: Mouse
Sample Types: Tissue Homogenates

(2016), Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor Sci Rep, 6(0):26490.
PMID: 27215684
Species: Mouse
Sample Types: Plasma

Mario Martínez-F (2016), PROTECTIVE EFFECTS OF HUMAN AND MOUSE SOLUBLE SCAVENGER-LIKE CD6 LYMPHOCYTE RECEPTOR IN A LETHAL MODEL OF POLYMICROBIAL SEPSIS Antimicrob. Agents Chemother, 0(0).
PMID: 27895015
Species: Mouse
Sample Types: Tissue Homogenates

Ana Lúcia Brunialti- (2016), Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury J. Nutr. Biochem., 39(0):93-100.
PMID: 27821289
Species: Mouse
Sample Types: Serum

Canli O et al. (2016), Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood, 127(1):139-48.
PMID: 26463424
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation J Immunol, 197(7):2653-64.
PMID: 27574298
Species: Mouse
Sample Types: Plasma

(2016), Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow Mol Cancer Res, 0(0).
PMID: 27489361
Species: Mouse
Sample Types: BALF

Rujin Huang (2016), Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations Sci. Total Environ., 0(0).
PMID: 27842959
Species: Mouse
Sample Types: Cell Culture Supernates

Nana Owusu-Boai (2016), Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner Immun Inflamm Dis, 4(4):413-426.
PMID: 27980776
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis PLoS ONE, 11(5):e0154630.
PMID: 27159398
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy Nat Commun, 7(0):13894.
PMID: 28004802
Species: Human
Sample Types: Cell Culture Supernates

(2016), Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer BMC Cancer, 16(1):897.
PMID: 27855669
Species: Mouse
Sample Types: Tissue Homogenates

(2016), Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization Sci Rep, 6(0):26955.
PMID: 27230787
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition PLoS Pathog, 12(5):e1005644.
PMID: 27223610
Species: Mouse
Sample Types: Plasma

Flavia Regina Sobreira Corrêa (2016), Brazilian red propolis improves cutaneous wound healing suppressing inflammation-associated transcription factor NF?B Biomed. Pharmacother, 86(0):162-171.
PMID: 27978495
Species: Mouse
Sample Types: Cell Culture Supernates

Istvan Szatmari (2016), Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3 J. Immunol., 0(0).
PMID: 27852743
Species: Mouse
Sample Types: Cell Culture Supernates

Andrey Lozhkin (2016), NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis J. Mol. Cell. Cardiol, 0(0).
PMID: 27986445
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3 J. Biomed. Sci, 23(1):85.
PMID: 27903271
Species: Mouse
Sample Types: Tissue Homogenates

Oyama L et al. (2016), Jucara pulp supplementation improves glucose tolerance in mice. Diabetol Metab Syndr, 8(0):8.
PMID: 26807159
Species: Mouse
Sample Types: BALF

(2016), C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils J Immunol, 196(5):2319-26.
PMID: 26800872
Species: Mouse
Sample Types: Serum

(2016), The circadian clock regulates inflammatory arthritis FASEB J, 0(0).
PMID: 27488122
Species: Mouse
Sample Types: Cell Culture Supernates

Arne Yndestad (2016), Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts Biochim. Biophys. Acta, 0(0).
PMID: 27845246
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Toll-Like Receptor 2 recognizes Orientia tsutsugamushi and increases susceptibility to murine experimental scrub typhus Infect Immun, 0(0).
PMID: 27620720
Species: Mouse
Sample Types: Tissue Homogenates

(2016), Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia MBio, 7(5).
PMID: 27624128
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Immune Cell-Conditioned Media Suppress Prostate Cancer PC-3 Cell Growth Correlating With Decreased Proinflammatory/Anti-inflammatory Cytokine Ratios in the Media Using 5 Selected Crude Polysaccharides Integr Cancer Ther, 15(4):NP13-NP25.
PMID: 27130724
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus Eur. J. Immunol., 0(0).
PMID: 27800616
Species: Mouse
Sample Types: Cell Culture Supernates

(2016), Traditional medicine, Sobokchukeo?Tang, modulates the inflammatory response in adipocytes and macrophages Mol Med Rep, 0(0).
PMID: 27959437
Species: Mouse
Sample Types: Cell Culture Supernates

O'Sullivan C et al. (2015), The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures. J Neuroinflammation, 13(1):31.
PMID: 26856814
Species: Mouse
Sample Types: Cell Culture Supernates

Bonapace L et al. (2015), Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature, 515(7525):130-3.
PMID: 25337873
Species: Mouse
Sample Types: Cell Culture Supernates

Fieber C et al. (2015), Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2. PLoS ONE, 10(3):e0119727.
PMID: 25756897
Species: Mouse
Sample Types: Cell Culture Supernates

Yang Y et al. (2015), The inability of wild-type rabies virus to activate dendritic cells is dependent on the glycoprotein and correlates with its low level of the de novo-synthesized leader RNA. J Virol, 89(4):2157-69.
PMID: 25473057
Species: Mouse
Sample Types: Cell Culture Supernates

Pfarr K et al. (2015), Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin. PLoS ONE, 10(3):e0118802.
PMID: 25756279
Species: Mouse
Sample Types: Tissue Homogenates

Zhao Y et al. (2015), Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol, 8(4):896-905.
PMID: 25492474
Species: Mouse
Sample Types: Cell Culture Supernates

Levy O et al. (2015), Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration. EMBO Mol Med, 7(2):211-26.
PMID: 25604058
Species: Mouse
Sample Types: BALF

Hoegl S et al. (2015), Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury. J Immunol, 195(4):1815-24.
PMID: 26188061
Species: Mouse
Sample Types: Plasma

Wang H et al. (2015), Des-Aspartate-Angiotensin I Attenuates Mortality of Mice Exposed to Gamma Radiation via a Novel Mechanism of Action. PLoS ONE, 10(9):e0138009.
PMID: 26378927
Species: Mouse
Sample Types: BALF

Windolf C et al. (2015), Lysostaphin-coated titan-implants preventing localized osteitis by Staphylococcus aureus in a mouse model. PLoS ONE, 9(12):e115940.
PMID: 25536060
Species: Mouse
Sample Types: Cell Culture Supernates

Fleming B et al. (2015), The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. J Leukoc Biol, 98(3):395-407.
PMID: 26048978
Species: Mouse
Sample Types: Cell Culture Supernates

Semple F et al. (2015), Human beta-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid. PLoS Genet, 11(12):e1005673.
PMID: 26646717
Species: Mouse
Sample Types: Tissue Homogenates

Jovicic N et al. (2015), Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding. PLoS ONE, 10(7):e0134089.
PMID: 26218873
Species: Mouse
Sample Types: BALF

Sundar et al. (2015), Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD. Sci Rep, 4(0):9927.
PMID: 25923474
Species: Mouse
Sample Types: BALF

Shah D et al. (2015), C1q Deficiency Promotes Pulmonary Vascular Inflammation and Enhances the Susceptibility of the Lung Endothelium to Injury. J Biol Chem, 290(49):29642-51.
PMID: 26487714
Species: Mouse
Sample Types: Serum

Kim S et al. (2015), Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production. J Immunol, 194(9):4498-506.
PMID: 25821218
Species: Mouse
Sample Types: BALF

Schliehe C et al. (2015), The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol, 16(1):67-74.
PMID: 25419628
Species: Mouse
Sample Types: Cell Culture Supernates

Goyden J et al. (2015), The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation. PLoS ONE, 10(6):e0127230.
PMID: 26030441
Species: Mouse
Sample Types: Tissue Homogenates

Talabot-Ayer D et al. (2015), Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice. J Immunol, 194(2):750-60.
PMID: 25505285
Species: Mouse
Sample Types: Cell Culture Supernates

Kitai Y et al. (2015), Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem, 290(2):1269-80.
PMID: 25451939
Species: Mouse
Sample Types: Cell Culture Supernates

Kortman G et al. (2015), Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens. Eur J Immunol, 45(9):2553-67.
PMID: 26046550
Species: Mouse
Sample Types: Tissue Homogenates

Avila L et al. (2015), Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury. PLoS ONE, 10(9):e0137273.
PMID: 26332044
Species: Mouse
Sample Types: Cell Culture Supernates

Wu Y et al. (2015), Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. J Immunol, 195(6):2612-23.
PMID: 26238491
Species: Mouse
Sample Types: Cell Culture Supernates

Kanagavelu S et al. (2015), TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis. Mucosal Immunol, 8(2):296-306.
PMID: 25073675
Species: Mouse
Sample Types: Cell Culture Supernates

Tan Z et al. (2015), Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism. J Immunol, 194(12):6082-9.
PMID: 25964487
Species: Mouse
Sample Types: Cell Culture Supernates

Cengiz P et al. (2014), Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation. PLoS ONE, 9(1):e84294.
PMID: 24392123
Species: Mouse
Sample Types: Cell Culture Supernates

Rigby R et al. (2014), RNA:DNA hybrids are a novel molecular pattern sensed by TLR9. EMBO J, 33(6):542-58.
PMID: 24514026
Species: Mouse
Sample Types: Cell Culture Supernates

Yan et al. (2014), Role of OGR1 in myeloid-derived cells in prostate cancer. Oncogene, 33(2):157-64.
PMID: 23222714
Species: Mouse
Sample Types: BALF

Benmohamed F et al. (2014), Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection. PLoS ONE, 9(3):e90466.
PMID: 24595157
Species: Mouse
Sample Types: Cell Culture Supernates

Xie N et al. (2014), miR-27a regulates inflammatory response of macrophages by targeting IL-10. J Immunol, 193(1):327-34.
PMID: 24835395
Species: Mouse
Sample Types: Tissue Homogenates

Menezes-Garcia Z et al. (2014), Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion. Obesity (Silver Spring), 22(3):663-72.
PMID: 24339378
van den Bosch M et al. (2014), LPS induces the degradation of programmed cell death protein 4 (PDCD4) to release Twist2, activating c-Maf transcription to promote interleukin-10 production. J Biol Chem, 289(33):22980-90.
PMID: 24982420
Species: Mouse
Sample Types: Cell Culture Supernates

Peano C et al. (2014), Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis. PLoS ONE, 9(3):e93009.
PMID: 24671187
Species: Mouse
Sample Types: Tissue Homogenates

De Filippo K et al. (2014), A new protective role for S100A9 in regulation of neutrophil recruitment during invasive pneumococcal pneumonia. FASEB J, 28(8):3600-8.
PMID: 24776746
Species: Mouse
Sample Types: Cell Culture Supernates

Biswas R et al. (2014), Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO. J Immunol Res, 2014(0):304180.
PMID: 25054161
Species: Mouse
Sample Types: Cell Culture Supernates

Huang B et al. (2014), Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells. Mol Med Rep, 10(2):1077-83.
PMID: 24898576
Species: Mouse
Sample Types: Cell Culture Supernates

Li et al. (2014), Artesunate reduces serum lipopolysaccharide in cecal ligation/puncture mice via enhanced LPS internalization by macrophages through increased mRNA expression of scavenger receptors. Int J Mol Sci, 15(1):1143-61.
PMID: 24441569
Species: Mouse
Sample Types: Cell Culture Supernates

Barra et al. (2014), Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. PLoS ONE, 9(12):e114799.
PMID: 25517731
Species: Mouse
Sample Types: Plasma

Thomson et al. (2014), Peripheral inflammation is associated with remote global gene expression changes in the brain. J Neuroinflammation, 11(0):73.
PMID: 24708794
Species: Mouse
Sample Types: Cell Culture Supernates

Feng J et al. (2014), miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease. Lipids Health Dis, 13(0):27.
PMID: 24502419
Species: Mouse
Sample Types: Cell Culture Supernates

Dinis M et al. (2014), The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type. PLoS ONE, 9(7):e101464.
PMID: 24991887
Species: Mouse
Sample Types: Cell Culture Supernates

Dowling J et al. (2014), Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation. J Biol Chem, 289(10):6429-37.
PMID: 24407287
Species: Mouse
Sample Types: Plasma

Csoka B et al. (2014), A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation. Diabetes, 63(3):850-66.
PMID: 24194503
Species: Mouse
Sample Types: Cell Culture Supernates

Dong X et al. (2014), Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection. Infect Immun, 82(5):1833-9.
PMID: 24549331
Species: Mouse
Sample Types: Peritoneal Fluid

Dumas A et al. (2014), The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis. PLoS Pathog, 10(5):e1004150.
PMID: 24875775
Species: Mouse
Sample Types: Tissue Homogenates

Lv J et al. (2014), Pulmonary immune responses to 2009 pandemic influenza A (H1N1) virus in mice. BMC Infect Dis, 14(0):197.
PMID: 24725777
Species: Mouse
Sample Types: BALF

Mancuso P et al. (2014), No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice. PLoS ONE, 9(9):e106420.
PMID: 25203099
Species: Mouse
Sample Types: BALF

Blanchet C et al. (2014), Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection. PLoS ONE, 9(1):e87927.
PMID: 24498223
Haste L et al. (2014), Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways. Infect Immun, 82(8):3289-98.
PMID: 24866797
Species: Mouse
Sample Types: BALF

Teijaro J et al. (2014), Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection. Proc Natl Acad Sci U S A, 111(10):3799-804.
PMID: 24572573
Species: Mouse
Sample Types: Tissue Homogenates

Redlich S et al. (2014), Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections. J Neuroinflammation, 11(0):108.
PMID: 24927796
Species: Mouse
Sample Types: Tissue Homogenates

(2014), Role of IL-1ÃŽÂ² in experimental cystic fibrosis upon P. aeruginosa infection. PLoS ONE, 9(12):e114884.
PMID: 25500839
Species: Mouse
Sample Types: BALF

Goncalves-de-Albuquerque C et al. (2014), Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor. Respir Res, 15(0):93.
PMID: 25265888
Species: Mouse
Sample Types: Tissue Homogenates

Kim H et al. (2014), S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model. PLoS ONE, 9(2):e88924.
PMID: 24586443
Species: Mouse
Sample Types: Serum

Takaoka et al. (2014), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice. Sci Rep, 4(0):5204.
PMID: 24902773
Species: Mouse
Sample Types: Tissue Homogenates

Brant F et al. (2014), Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection. Infect Immun, 82(8):3127-40.
PMID: 24818665
Species: Mouse
Sample Types: Cell Culture Supernates

Viennois E et al. (2014), Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer. Lab Invest, 94(9):950-65.
PMID: 25068660
Species: Mouse
Sample Types: Cell Culture Supernates

Assi H et al. (2014), Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM. PLoS ONE, 9(5):e96318.
PMID: 24806510
Species: Mouse
Sample Types: Serum

Ferreira A et al. (2014), PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis. J Immunol, 192(5):2357-65.
PMID: 24489087
Species: Mouse
Sample Types: Cell Culture Supernates

Gleeson E et al. (2014), Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells. Haematologica, 99(1):185-93.
PMID: 23872307
Species: Mouse
Sample Types: Cell Culture Supernates

Tatano Y et al. (2014), Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep, 4(0):4146.
PMID: 24553452
Species: Mouse
Sample Types: BALF

Gold E et al. (2014), 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling. Proc Natl Acad Sci U S A, 111(29):10666-71.
PMID: 24994901
Species: Mouse
Sample Types: Cell Culture Supernates

Noelker C et al. (2014), Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease. J Neuroinflammation, 11(0):86.
PMID: 24886419
Species: Mouse
Sample Types: BALF

Walsh K et al. (2014), Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy. J Virol, 88(11):6281-93.
PMID: 24672024
Species: Mouse
Sample Types: Cell Culture Supernates

Djukic M et al. (2014), Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells. Infect Immun, 82(6):2585-94.
PMID: 24686054
Species: Mouse
Sample Types: BALF

Dreymueller D et al. (2014), Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes. J Immunol, 192(2):722-31.
PMID: 24342803
Species: Mouse
Sample Types: Tissue Homogenates

Alvarez-Fischer D et al. (2013), Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model. PLoS ONE, 8(4):e61700.
PMID: 23637888
Species: Mouse
Sample Types: Cell Culture Supernates

Wu Z et al. (2013), Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation. PLoS ONE, 8(3):e58560.
PMID: 23484036
Species: Mouse
Sample Types: Cell Culture Supernates

Waddell A et al. (2013), Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice. J Immunol, 190(9):4773-85.
PMID: 23562811
Species: Mouse
Sample Types: Cell Culture Supernates

Gonzalez Y et al. (2013), A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages. PLoS ONE, 8(12):e84107.
PMID: 24358331
Species: Mouse
Sample Types: Cell Culture Supernates

Hosoi T et al. (2013), ER stress-mediated regulation of immune function under glucose-deprived condition in glial cells: up- and down-regulation of PGE2 + IFNgamma-induced IL-6 and iNOS expressions. Biochem Biophys Res Commun, 441(2):525-8.
PMID: 24177007
Species: Mouse
Sample Types: Plasma

Crotty Alexander et al. (2013), Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection. PLoS ONE, 8(12):e84481.
PMID: 24386389
Species: Mouse
Sample Types: Tissue Homogenates

Fevre C et al. (2013), A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes. EMBO Mol Med, 5(4):516-30.
PMID: 23554169
Species: Mouse
Sample Types: Serum

Georgiev P et al. (2013), Genetic deletion of the HIF-1alpha isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model. Eur J Immunol, 43(3):655-66.
PMID: 23208786
Species: Mouse
Sample Types: Cell Culture Supernates

Marinho F et al. (2013), Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection. Eur J Immunol, 43(9):2373-85.
PMID: 23716075
Species: Mouse
Sample Types: Plasma

Kwiecinski J et al. (2013), Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway. Infect Immun, 81(4):1114-20.
PMID: 23340309
Species: Mouse
Sample Types: Tissue Homogenates

Kempuraj D et al. (2013), The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice. PLoS ONE, 8(2):e56866.
PMID: 23418608
Species: Mouse
Sample Types: BALF

Everitt et al. (2013), Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model. PLoS ONE, 8(11):e80723.
PMID: 24278312
Species: Mouse
Sample Types: Cell Culture Supernates

Moseman et al. (2013), Mannose receptor 1 mediates cellular uptake and endosomal delivery of CpG-motif containing oligodeoxynucleotides. J Immunol, 191(11):5615-24.
PMID: 24184555
Species: Mouse
Sample Types: Cell Culture Supernates

Zhou H et al. (2013), IRAK-M mediates Toll-like receptor/IL-1R-induced NFkappaB activation and cytokine production. EMBO J, 32(4):583-96.
PMID: 23376919
Species: Mouse
Sample Types: Cell Culture Supernates

Park Y et al. (2013), TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis. PLoS Pathog, 9(10):e1003646.
PMID: 24098117
Species: Mouse
Sample Types: Cell Culture Supernates

Wu Z et al. (2013), Calcineurin-Rcan1 interaction contributes to stem cell factor-mediated mast cell activation. J Immunol, 191(12):5885-94.
PMID: 24218457
Species: Mouse
Sample Types: Cell Culture Supernates

Beynon A et al. (2013), Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones. J Neuroinflammation, 10(0):40.
PMID: 23509933
Species: Mouse
Sample Types: Cell Culture Supernates

Qi et al. (2012), Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization. J Biol Chem, 287(39):32617-29.
PMID: 22865861
Species: Mouse
Sample Types: Cell Culture Supernates

Chuquimia OD et al. (2012), The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. PLoS ONE, 7(2):e32125.
PMID: 22393384
Species: Mouse
Sample Types: Serum

Veliz Rodriguez T et al. (2012), Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun., 80(1):100-9.
PMID: 22025515
Species: Mouse
Sample Types: Plasma

Pini M et al. (2012), Rosiglitazone improves survival and hastens recovery from pancreatic inflammation in obese mice. PLoS ONE, 7(7):e40944.
PMID: 22815875
Species: Mouse
Sample Types: Cell Culture Supernates

Kohler T et al. (2012), Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration. Eur. J. Immunol., 42(5):1226-36.
PMID: 22539295
Species: Mouse
Sample Types: Serum

(2012), Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J. Immunol., 189(4):1911-9.
PMID: 22786765
Species: Mouse
Sample Types: BALF

Le Goffic R et al. (2011), Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein. PLoS Pathog., 7(8):e1002202.
PMID: 21901097
Species: Mouse
Sample Types: BALF

Walsh KB et al. (2011), Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus. Proc. Natl. Acad. Sci. U.S.A., 108(29):12018-23.
PMID: 21715659
Species: Mouse
Sample Types: BALF

Teijaro JR et al. (2011), Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Cell, 146(6):980-91.
PMID: 21925319
Species: Mouse
Sample Types: BALF

Machado GB et al. (2011), Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis. Respir. Res., 12(0):104.
PMID: 21819560
Species: Mouse
Sample Types: BALF

Barber DL et al. (2011), CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition. J. Immunol., 186(3):1598-607.
PMID: 21172867
Species: Mouse
Sample Types: Tissue Homogenates

Moalli F et al. (2011), The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa. J. Immunol., 186(9):5425-34.
PMID: 21441447
Species: Mouse
Sample Types: Cell Culture Supernates

El-Behi M et al. (2011), The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 12(6):568-75.
PMID: 21516111
Species: Mouse
Sample Types: Thoracic Cavity Fluid

Specht S et al. (2011), CCL17 controls mast cells for the defense against filarial larval entry. J. Immunol., 186(8):4845-52.
PMID: 21398605
Species: Mouse
Sample Types: BALF

McMillan DH et al. (2011), Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation. Am. J. Pathol., 179(1):125-33.
PMID: 21703398
Species: Mouse
Sample Types: BALF

Steinwede K et al. (2011), Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia. J. Immunol., 187(10):5346-56.
PMID: 22003204
Species: Mouse
Sample Types: Cell Culture Supernates

Chang CH et al. (2010), A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation. J. Thromb. Haemost., 8(11):2563-70.
PMID: 20738764
Species: Mouse
Sample Types: Serum

Barra NG et al. (2010), Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes. Obesity (Silver Spring), 18(8):1601-7.
PMID: 20019685
Species: Mouse
Sample Types: Cell Culture Supernates

Sheldon IM et al. (2010), Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium. PLoS ONE, 5(9):e12906.
PMID: 20877575
Species: Mouse
Sample Types: Cell Culture Supernates

Burton OT et al. (2010), Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens. Eur. J. Immunol., 40(8):2221-9.
PMID: 20480503
Species: Mouse
Sample Types: Cell Culture Supernates

Zhang X et al. (2010), A critical role for C5L2 in the pathogenesis of experimental allergic asthma. J. Immunol., 185(11):6741-52.
PMID: 20974988
Species: Mouse
Sample Types: BALF

Zhu M et al. (2010), Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice. Am. J. Respir. Cell Mol. Biol., 43(4):487-97.
PMID: 19915153
Species: Mouse
Sample Types: Cell Culture Supernates

Sellge G et al. (2010), Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity. J. Immunol., 184(4):2076-85.
PMID: 20089698
Species: Mouse
Sample Types: Serum

Kwon OJ et al. (2010), A hypoxia- and alpha-fetoprotein-dependent oncolytic adenovirus exhibits specific killing of hepatocellular carcinomas. Clin. Cancer Res., 16(24):6071-82.
PMID: 21169258
Species: Mouse
Sample Types: Serum

Lamacchia C et al. (2010), Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice. J. Immunol., 185(0):2516-24.
PMID: 20639493
Species: Mouse
Sample Types: Plasma

Jaffre F et al. (2009), Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy. Circ. Res., 104(1):113-23.
PMID: 19023134
Species: Mouse
Sample Types: Cell Culture Supernates

Wang S et al. (2009), Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse. Atherosclerosis, 204(1):147-55.
PMID: 18842266
Species: Mouse
Sample Types: Cell Culture Supernates

Nold-Petry CA et al. (2009), Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS). J. Biol. Chem., 0(0).
PMID: 19592492
Species: Mouse
Sample Types: Tissue Homogenates

Lagler H et al. (2009), TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J. Immunol., 183(3):2027-36.
PMID: 19596984
Species: Mouse
Sample Types: BALF

Couillin I et al. (2009), IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. J. Immunol., 183(12):8195-202.
PMID: 20007584
Species: Mouse
Sample Types: BALF

Neveu WA et al. (2009), IL-6 is required for airway mucus production induced by inhaled fungal allergens. J. Immunol., 183(3):1732-8.
PMID: 19592651
Species: Mouse
Sample Types: Tissue Homogenates

Aronoff DM et al. (2009), E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J. Immunol., 183(4):2642-9.
PMID: 19635910
Species: Mouse
Sample Types: Tissue Homogenates

Christophi GP et al. (2009), Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease. J. Virol., 83(2):522-39.
PMID: 18987138
Species: Mouse
Sample Types: Serum

Matsuda N et al. (2009), Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis. Crit. Care Med., 37(10):2791-9.
PMID: 19707125
Species: Mouse
Sample Types: BALF

Darniot M et al. (2009), Age-associated aggravation of clinical disease after primary metapneumovirus infection of BALB/c mice. J. Virol., 83(7):3323-32.
PMID: 19144706
Species: Mouse
Sample Types: BALF

Doz E et al. (2008), Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J. Immunol., 180(2):1169-78.
PMID: 18178857
Species: Mouse
Sample Types: Cell Culture Supernates

Florindo HF et al. (2008), Streptococcus equi antigens adsorbed onto surface modified poly-epsilon-caprolactone microspheres induce humoral and cellular specific immune responses. Vaccine, 26(33):4168-77.
PMID: 18599166
Species: Mouse
Sample Types: Cell Culture Supernates

Novitskiy SV et al. (2008), Adenosine receptors in regulation of dendritic cell differentiation and function. Blood, 112(5):1822-31.
PMID: 18559975
Species: Mouse
Sample Types: BALF

Williams AS et al. (2008), Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13. Eur. Respir. J., 32(3):571-8.
PMID: 18417511
Species: Mouse
Sample Types: BALF

Leite-Junior JH et al. (2008), Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice. Crit. Care Med., 36(9):2621-8.
PMID: 18728474
Species: Mouse
Sample Types: Tissue Homogenates

Lembo A et al. (2008), Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia. J. Immunol., 180(11):7574-81.
PMID: 18490759
Species: Mouse
Sample Types: Cell Culture Supernates

Tiwari N et al. (2008), VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways. Blood, 111(7):3665-74.
PMID: 18203950
Species: Mouse
Sample Types: Tissue Homogenates

Bozza S et al. (2008), Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J. Immunol., 180(6):4022-31.
PMID: 18322211
Species: Mouse
Sample Types: Cell Culture Supernates

Hudson CA et al. (2008), Induction of IL-33 expression and activity in central nervous system glia. J. Leukoc. Biol., 84(3):631-43.
PMID: 18552204
Species: Mouse
Sample Types: Cell Culture Supernates

Kaya Z et al. (2008), Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation, 118(20):2063-72.
PMID: 18955666
Species: Mouse
Sample Types: Cell Culture Supernates

Wan S et al. (2008), Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum., 8(0):1741-50.
PMID: 18512810
Species: Human
Sample Types: Cell Culture Supernates

Arias MA et al. (2007), Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes. J. Immunol., 179(12):8381-91.
PMID: 18056384
Species: Mouse
Sample Types: Serum

Natarajan A et al. (2007), The EGF receptor is required for efficient liver regeneration. Proc. Natl. Acad. Sci. U.S.A., 104(43):17081-6.
PMID: 17940036
Species: Mouse
Sample Types: Cell Culture Supernates

Schell JB et al. (2007), Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. J. Neuroimmunol., 189(1):75-87.
PMID: 17698208
Species: Mouse
Sample Types: Cell Culture Supernates

Tjwa M et al. (2007), Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood, 111(8):4096-105.
PMID: 18156494
Species: Mouse
Sample Types: Cell Culture Supernates

Sugiyama K et al. (2007), Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells. Clin. Exp. Immunol., 147(3):540-6.
PMID: 17302905
Species: Mouse
Sample Types: Cell Culture Supernates

Fritz JH et al. (2007), Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity, 26(4):445-59.
PMID: 17433730
Species: Mouse
Sample Types: Serum

Vijay-Kumar M et al. (2007), Deletion of TLR5 results in spontaneous colitis in mice. J. Clin. Invest., 117(12):3909-21.
PMID: 18008007
Species: Mouse
Sample Types: Plasma

Hegde A et al. (2007), Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. J. Leukoc. Biol., 82(3):678-85.
PMID: 17565047
Species: Mouse
Sample Types: Cell Culture Supernates

Tsakiri N et al. (2007), Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones. Mol. Cell. Neurosci., 37(1):110-8.
PMID: 17933551
Species: Mouse
Sample Types: Tissue Homogenates

Tsuruta Y et al. (2007), Involvement of vitronectin in lipopolysaccaride-induced acute lung injury. J. Immunol., 179(10):7079-86.
PMID: 17982099
Species: Mouse
Sample Types: Plasma

Wilmanski J et al. (2007), Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis. Crit. Care Med., 35(2):510-8.
PMID: 17205013
Species: Mouse
Sample Types: Cell Culture Supernates

Tsakiri N et al. (2007), Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones. Br. J. Pharmacol., 153(4):775-83.
PMID: 18059318
Species: Mouse
Sample Types: Cell Culture Supernates

Hung LC et al. (2007), A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways. Biochem. Pharmacol., 73(12):1957-70.
PMID: 17445776
Species: Mouse
Sample Types: BALF

Gasse P et al. (2007), IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J. Clin. Invest., 117(12):3786-99.
PMID: 17992263
Species: Mouse
Sample Types: Serum

Robertson SA et al. (2007), Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice. Biol. Reprod., 76(5):738-48.
PMID: 17215490
Species: Mouse
Sample Types: Air Pouch Exudate

Rabe B et al. (2007), Transgenic blockade of interleukin 6 transsignaling abrogates inflammation. Blood, 111(3):1021-8.
PMID: 17989316
Species: Mouse
Sample Types: Cell Culture Supernates

Cheng W et al. (2007), Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect. Immun., 76(2):515-22.
PMID: 18025098
Species: Mouse
Sample Types: Cell Culture Supernates

Hwang SA et al. (2007), Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis. Vaccine, 25(37):6730-43.
PMID: 17698261
Species: Mouse
Sample Types: Tissue Homogenates

Fuse ET et al. (2007), Role of Toll-like receptor 2 in recognition of Legionella pneumophila in a murine pneumonia model. J. Med. Microbiol., 56(0):305-12.
PMID: 17314358
Species: Mouse
Sample Types: Serum

Robertson SA et al. (2006), Essential role for IL-10 in resistance to lipopolysaccharide-induced preterm labor in mice. J. Immunol., 177(7):4888-96.
PMID: 16982931
Species: Mouse
Sample Types: BALF

Allen GB et al. (2006), Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury. Am. J. Physiol. Lung Cell Mol. Physiol., 291(4):L710-7.
PMID: 16698851
Species: Mouse
Sample Types: Plasma

Bruhn A et al. (2006), Effects of dexamethasone on macrophage migration inhibitory factor production in sepsis. Shock, 26(2):169-73.
PMID: 16878025
Species: Mouse
Sample Types: Cell Culture Supernates

Lin TY et al. (2006), A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet. Immunol. Immunopathol., 114(3):320-34.
PMID: 17027994
Species: Mouse
Sample Types: Cell Culture Supernates

Vizzardelli C et al. (2006), Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis. Eur. J. Immunol., 36(6):1504-15.
PMID: 16708398
Species: Mouse
Sample Types: Cell Culture Supernates

Powell JM et al. (2006), The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production. J. Interferon Cytokine Res., 26(1):34-9.
PMID: 16426146
Species: Mouse
Sample Types: Serum

Lu FL et al. (2006), Increased pulmonary responses to acute ozone exposure in obese db/db mice. Am. J. Physiol. Lung Cell Mol. Physiol., 290(5):L856-65.
PMID: 16373670
Species: Mouse
Sample Types: Peritoneal Fluid

Gomes RN et al. (2006), Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis. Shock, 26(1):41-9.
PMID: 16783197
Species: Mouse
Sample Types: Cell Culture Supernates

Moschos SA et al. (2005), Comparative immunomodulatory properties of a chitosan-MDP adjuvant combination following intranasal or intramuscular immunisation. Vaccine, 23(16):1923-30.
PMID: 15734064
Species: Mouse
Sample Types: Serum

Delale T et al. (2005), MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J. Immunol., 175(10):6723-32.
PMID: 16272328
Species: Mouse
Sample Types: BALF

Allen L et al. (2005), Pyocyanin production by Pseudomonas aeruginosa induces neutrophil apoptosis and impairs neutrophil-mediated host defenses in vivo. J. Immunol., 174(6):3643-9.
PMID: 15749902
Species: Mouse
Sample Types: Pleural Fluid

Amendoeira FC et al. (2005), Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest. Biol. Pharm. Bull., 28(6):1010-5.
PMID: 15930736
Species: Mouse
Sample Types: Cell Culture Supernates

Aviles H et al. (2004), Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions. J. Appl. Physiol., 97(4):1437-44.
PMID: 15194672
Species: Mouse
Sample Types: Cell Culture Supernates

Fremond CM et al. (2004), Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88. J. Clin. Invest., 114(12):1790-9.
PMID: 15599404
Species: Mouse
Sample Types: Serum

Yarovinsky TO et al. (2003), Adenoviral infection decreases mortality from lipopolysaccharide-induced liver failure via induction of TNF-alpha tolerance. J. Immunol., 171(5):2453-60.
PMID: 12928393
Species: Mouse
Sample Types: Cell Culture Supernates

Takahashi M et al. (2003), Cytokine production in association with phagocytosis of apoptotic cells by immature dendritic cells. Cell. Immunol., 226(2):105-15.
PMID: 14962498
Species: Human
Sample Types: Cell Culture Supernates

Cheng Y et al. (0), Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells. PLoS ON10(11):e0142283.
PMID: 26544976
Species: Mouse
Sample Types: Tissue Homogenates

Evans C et al. (0), ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease. Acta Neuropatho139(3):485-502.
PMID: 31982938

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Customer Reviews for Mouse IL-6 DuoSet ELISA (34)

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Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: A549 human lung carcinoma cell line

Verified Customer | Posted 12/05/2022
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 11/07/2022
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: BAL fluid

Verified Customer | Posted 07/21/2022

Very stable and simple
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Colon tissue

Verified Customer | Posted 05/26/2022
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum and Plasma

Verified Customer | Posted 03/11/2022

Used this kit for quantifying mouse IL-6 in serum samples, could see the detection but not strong in our samples. Standard curve looks good.
Mouse IL-6 DuoSet ELISA

Name: Rob Knight

Sample Tested: Cell Culture Media,RAW 264.7 mouse monocyte/macrophage cell line

Verified Customer | Posted 12/09/2021

RAW Cells cultured with 10ng/mL LPS for 24hrs
Mouse IL-6 DuoSet ELISA

Name: Martin Torres

Sample Tested: Adult small intestine

Verified Customer | Posted 09/24/2021

Mouse IL-6 was evaluated in intestinal tissues from C57BL/6J mice treated with Dextran sodium sulfate (DSS) as chemical pro-inflammatory drug aiming to simulate chronic colitis (DSS: 2.5%, 7 days treatment). Results were consistent to what was expected from this assay, and were in agreement with previous reports for this mouse strain. Treatments correspond to Moringa oleifera powder administered to mice (20 and 50% of total caloric content).
Mouse IL-6 DuoSet ELISA

Name: Ricardo Malvicini

Sample Tested: Cell culture supernatant

Verified Customer | Posted 09/10/2021
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/03/2021
Mouse IL-6 DuoSet ELISA

Name: Wuyi Wang

Sample Tested: NIH-3T3 mouse embryonic fibroblast cell line

Verified Customer | Posted 10/28/2020
Mouse IL-6 DuoSet ELISA

Name: Cristina Caldari

Sample Tested: RAW 264.7 mouse monocyte/macrophage cell line

Verified Customer | Posted 08/28/2020

Excellent kit. Easy to use, clear instructions, performs perfectly and consistently.
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: CHO Chinese hamster ovary cell line

Verified Customer | Posted 11/21/2019
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant,RAW 264.7 mouse monocyte/macrophage cell line

Verified Customer | Posted 11/10/2019
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: C2C12 Cell Culture Supernatants

Verified Customer | Posted 07/10/2019

We used this DuoSet for looking at IL-6 within the supernatant of C2C12 myotubes stimulated with various ligands. We were able to run the samples neat and received great results.
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: PT18 mouse mast/basophil cell line

Verified Customer | Posted 03/13/2019
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 12/17/2018
Mouse IL-6 DuoSet ELISA

Name: Ivan Luzardo

Sample Tested: Serum and Plasma

Verified Customer | Posted 12/11/2018
Mouse IL-6 DuoSet ELISA

Name: Ivan Luzardo

Sample Tested: 3T3-L1 mouse embryonic fibroblast adipose-like cell line

Verified Customer | Posted 12/11/2018
Mouse IL-6 DuoSet ELISA

Name: Cristina Perez-Ternero

Sample Tested: Plasma

Verified Customer | Posted 07/29/2018
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: BMDM

Verified Customer | Posted 03/28/2018
Mouse IL-6 DuoSet ELISA

Name: tusar giri

Sample Tested: mice lung extract,mice lung protein

Verified Customer | Posted 12/01/2017
Mouse IL-6 DuoSet ELISA

Name: Ella Zeldich

Sample Tested: mouse primary microglia cells

Verified Customer | Posted 11/22/2017

Excellent performance
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Peritoneal resident macrophages

Verified Customer | Posted 09/27/2017
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum and Plasma

Verified Customer | Posted 09/07/2017
Mouse IL-6 DuoSet ELISA

Name: Shubhanchi Nigam

Sample Tested: Cell culture supernatant

Verified Customer | Posted 07/14/2017
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Lung tissue

Verified Customer | Posted 05/02/2017
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 04/24/2017
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 04/18/2017

Reliable results and easy to follow protocol
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Cell culture supernatant

Verified Customer | Posted 10/06/2016
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: Skeletal muscle

Verified Customer | Posted 09/30/2016
Mouse IL-6 DuoSet ELISA

Name: Anonymous

Sample Tested: mouse serum

Verified Customer | Posted 08/04/2016
Mouse IL-6 DuoSet ELISA

Name: I Sundar

Sample Tested: mouse BAL fluid

Verified Customer | Posted 07/05/2016
Mouse IL-6 DuoSet ELISA, 15 Plate

Name: Jacqueline Kimmey

Sample Tested: murine lung homogenate

Verified Customer | Posted 04/08/2016

consistent results, easy to use
Mouse IL-6 DuoSet ELISA, 15 Plate

Name: Anonymous

Sample Tested: Purified Standard

Verified Customer | Posted 10/26/2015

50ul of murine IL-6 Capture antibody (2ug/mL) was coated per well of a 96 well plate at 4 degrees overnight. Purified mIL-6 standard was diluted (7 fold) and assayed to ensure the quality of the ELISA. Mouse IL-6 Detector antibody was added (2h @ RT) followed by a 20 min incubation with Streptavidin-HRP. Substrate solution was added to measure mIL-6 concentration according to the manufactures protocol. The standard curve looked great as can be seen by calculation of the R- squared value. Highly recommend doing ELISA's using kits from R&D. Buffer: 7-Fold dilution cruve was tried (only values that genrated a linear curve are shown)

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Mouse IL-6 DuoSet ELISA

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Background: IL-6

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Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA

Mouse IL-6 DuoSet ELISA, 15 Plate

Mouse IL-6 DuoSet ELISA, 15 Plate

Product Documents for Mouse IL-6 DuoSet ELISA

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