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Human/Mouse/Rat Activin A Quantikine ELISA Kit
R&D Systems, Inc. a Bio-Techne Brand
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Key Product Details
| Assay Length: | 5 hours |
| Sample Type & Volume Required Per Well: | Cell Culture Supernates (100 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Saliva (50 uL) |
| Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva |
| Sensitivity: | 7.85 pg/mL |
| Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva) |
| Human/Mouse/Rat Activin A Quantikine ELISA Kit Summary: | The Quantikine Human/Mouse/Rat Activin A Immunoassay is a 5.0 hour solid-phase ELISA designed to measure Activin A in human, mouse, or rat cell culture supernates, serum, plasma, and saliva. It contains CHO cell-expressed recombinant human/mouse/rat Activin A and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human/mouse/rat Activin A showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally expressed Activin A. |
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Human/Mouse/Rat Activin A ELISA Standard Curve |
Citations for Human/Mouse/Rat Activin A Quantikine ELISA Kit (55)
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Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat Activin A Quantikine ELISA Kit include:
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Species: Human
Sample Types: Serum
AL Queiroz et al. (2022), Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer Nature Communications, 13(1):4633.
PMID: 35941104 -
Species: Human
Sample Types: Cell Culture Supernates
K Li et al. (2021), Metallothionein-1G suppresses pancreatic cancer cell stemness by limiting activin A secretion via NF-&kappaB inhibition Theranostics, 11(7):3196-3212.
PMID: 33537082 -
Species: Human
Sample Types: Serum
E Terpos et al. (2021), Carfilzomib Improves Bone Metabolism in Patients with Advanced Relapsed/Refractory Multiple Myeloma: Results of the CarMMa Study Cancers, 13(6).
PMID: 33809268 -
Species: Human
Sample Types: Cell Culture Supernates
D Mori et al. (2021), Adipose-derived mesenchymal stem cells preserve cardiac function via ANT-1 in dilated cardiomyopathy hamster model Regenerative Therapy, 18(0):182-190.
PMID: 34307796 -
Species: Mouse
Sample Types: Serum
KA Cho et al. (2021), Mesenchymal Stem Cell-Derived Exosomes Protect Muscle Loss by miR-145-5p Activity Targeting Activin A Receptors Cells, 10(8).
PMID: 34440938 -
Species: Human
Sample Types: Cell Culture Supernates
G Mancinelli et al. (2021), Role of stromal activin A in human pancreatic cancer and metastasis in mice Scientific Reports, 11(1):7986.
PMID: 33846512 -
Species: Human
Sample Types: Cell Culture Supernates
N Mehta et al. (2021), miR299a-5p promotes renal fibrosis by suppressing the antifibrotic actions of follistatin Scientific Reports, 11(1):88.
PMID: 33420269 -
Species: Human
Sample Types: Cell Culture Supernates
M McAleavy et al. (2021), The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients Molecular and Cellular Biology, 0(0):MCB0046721.
PMID: 34723652 -
Species: Human
Sample Types: Cell Culture Supernates
J Bauer et al. (2020), Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling Sci Rep, 10(1):50.
PMID: 31919369 -
Species: Mouse
Sample Types: Plasma
AL Thomas et al. (2020), Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index Clin Transl Gastroenterol, 11(5):e00152.
PMID: 32358238 -
Species: Human
Sample Types: Placenta
RA Rahman et al. (2020), Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia Int J Mol Sci, 21(7).
PMID: 32260307 -
Species: Human
Sample Types: Serum
YL Tsai et al. (2020), Serum Activin A Levels and Renal Outcomes After Coronary Angiography Sci Rep, 10(1):3365.
PMID: 32099067 -
Species: Mouse
Sample Types: Tissue Homogenates
CT Werner et al. (2020), Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence Proc Natl Acad Sci U S A, 0(0).
PMID: 33020308 -
Species: Human
Sample Types: Plasma
MJ Schafer et al. (2020), The senescence-associated secretome as an indicator of age and medical risk JCI Insight, 5(12).
PMID: 32554926 -
Species: Mouse
Sample Types: Serum
C Pan et al. (2020), Prostate tumor-derived GDF11 accelerates androgen deprivation therapy-induced sarcopenia JCI Insight, 0(0).
PMID: 32078585 -
Species: Human
Sample Types: Cell Culture Supernates
B Soler Pala et al. (2020), Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner J. Immunol., 0(0).
PMID: 32591394 -
Species: Human
Sample Types: Serum
JN Justice et al. (2019), Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study EBioMedicine, 0(0).
PMID: 30616998 -
Species: Mouse
Sample Types: Tissue Homogenates
P Rentsch et al. (2019), Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on L-Dopa induced dyskinesia BMC Neurosci, 20(1):5.
PMID: 30760214 -
Species: Human
Sample Types: Cell Culture Supernates
K Fujiki et al. (2019), Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms Cell Death Differ., 0(0).
PMID: 30804470 -
Species: Human
Sample Types: Cell Culture Supernates
CN Tsai et al. (2019), Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells Sci Rep, 9(1):5197.
PMID: 30914776 -
Species: Human
Sample Types: Serum
Y Takei et al. (2019), Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis PLoS ONE, 14(10):e0223703.
PMID: 31613925 -
Species: Human
Sample Types: Cell Culture Supernates
A Oppezzo et al. (2019), Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia J. Clin. Invest., 0(0).
PMID: 31877112 -
Species: Human
Sample Types: Serum
JM Kim et al. (2019), Diagnostic and prognostic values of serum activin-a levels in patients with acute respiratory distress syndrome BMC Pulm Med, 19(1):115.
PMID: 31238942 -
Species: Mouse
Sample Types: Serum
A Lepletier et al. (2019), Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging Cell Rep, 27(13):3887-3901.e4.
PMID: 31242421 -
Species: Rat
Sample Types: Serum
J Hu et al. (2018), Activin A inhibition attenuates sympathetic neural remodeling following myocardial infarction in rats Mol Med Rep, 17(4):5074-5080.
PMID: 29393433 -
Species: Mouse
Sample Types: Cell Culture Supernates
M Shoji et al. (2018), Different murine-derived feeder cells alter the definitive endoderm differentiation of human induced pluripotent stem cells PLoS ONE, 13(7):e0201239.
PMID: 30048506 -
Species: Human
Sample Types: Cell Culture Supernates
CFD Rodrigues et al. (2018), Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells Sci Rep, 8(1):11573.
PMID: 30069023 -
Species: Human
Sample Types: Plasma
LV Barrios-Si et al. (2018), Activin subfamily peptides predict chronological age in humans Physiol Rep, 6(17):e13823.
PMID: 30178598 -
Species: Human
Sample Types: Serum
E Barruet et al. (2018), NF-?B/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification JCI Insight, 3(22).
PMID: 30429363 -
Species: Human
Sample Types: Serum
Laura Hildebrand (2017), Trace element and cytokine concentrations in patients with Fibrodysplasia Ossificans Progressiva (FOP): A case control study J Trace Elem Med Biol, 39(0):186-192.
PMID: 27908413 -
Species: Human
Sample Types: Plasma
AT Amaraseker et al. (2017), Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults PLoS ONE, 12(5):e0174435.
PMID: 28489857 -
Species: Human
Sample Types: Whole Cells
F Sallustio et al. (2017), Inhibin-A and Decorin Secreted by Human Adult Renal Stem/Progenitor Cells Through the TLR2 Engagement Induce Renal Tubular Cell Regeneration Sci Rep, 7(1):8225.
PMID: 28811645 -
Species: Mouse
Sample Types: Tissue Homogenates
S Stayte et al. (2017), Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo PLoS ONE, 12(1):e0167211.
PMID: 28121982 -
Species: Human
Sample Types: Serum
E Latres et al. (2017), Activin A more prominently regulates muscle mass in primates than does GDF8 Nat Commun, 8(0):15153.
PMID: 28452368 -
Species: Ovine
Sample Types: Plasma
A Abdalmula et al. (2017), Immunoselected STRO-3(+) mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis Stem Cell Res Ther, 8(1):22.
PMID: 28173831 -
Species: Rat
Sample Types: Tissue Homogenates
ZJ Wang et al. (2017), Activin A is increased in the nucleus accumbens following a cocaine binge Sci Rep, 7(0):43658.
PMID: 28272550 -
Species: Mouse
Sample Types: Plasma
R Barreto et al. (2017), ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass Sci Rep, 7(1):14470.
PMID: 29089584 -
Species: Mouse
Sample Types: Serum
Applications: ELISA CaptureJonas J Staudacher et al. (2017), Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target. Scientific Reports, 0(0):2045-2322.
PMID: 28986573 -
Species: Mouse
Sample Types: Plasma
Edward O List (2016), Diet-induced weight loss is sufficient to reduce senescent cell number in white adipose tissue of weight-cycled mice Nutr Healthy Aging, 4(1):95-99.
PMID: 28035346 -
Species: Mouse
Sample Types: Cell Culture Supernates
(2016), A Key Role for Inhibins in Dendritic Cell Maturation and Function PLoS ONE, 11(12):e0167813.
PMID: 27936218 -
Species: Human
Sample Types: Cell Culture Supernates
(2016), Activin A programs the differentiation of human TFH cells Nat Immunol, 17(8):976-84.
PMID: 27376469 -
Species: Human
Sample Types: Serum
S Senapati et al. (2016), Predicting first trimester pregnancy outcome: derivation of a multiple marker test Fertil. Steril., 106(7):1725-1732.e3.
PMID: 28340932 -
Species: Human
Sample Types: Plasma
(2016), Late acute graft versus host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors Blood, 0(0).
PMID: 27625357 -
Tonia L Vincent (2016), Acute Molecular Changes in Synovial Fluid Following Human Knee Injury: Association With Early Clinical Outcomes Arthritis rheumatology (Hoboken, N.J.), 2016;68(9):2129-40.
PMID: 26991527 -
Species: Mouse
Sample Types: Urine
Yoshihisa Nojima (2016), Involvement of Infiltrating Macrophage-derived Activin A in the Progression of Renal Damage in MRL-lpr Mice Am. J. Physiol. Renal Physiol., 0(0):ajprenal.0019.
PMID: 27881396 -
Species: Human
Sample Types: Cell Culture Supernates
Wilson C et al. (2015), The differential anti-tumour effects of zoledronic acid in breast cancer - evidence for a role of the activin signaling pathway. BMC Cancer, 15(0):55.
PMID: 25884855 -
Species: Human
Sample Types: Cell Culture Supernates
Ungefroren H et al. (2015), Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-beta. PLoS ONE, 10(2):e0118097.
PMID: 25707005 -
Species: Human
Sample Types: Cell Culture Supernates
Li C et al. (2014), PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism. Cell Signal, 26(7):1369-78.
PMID: 24637302 -
Species: Human
Sample Types: Serum
Naf S et al. (2014), Serum activin A and follistatin levels in gestational diabetes and the association of the Activin A-Follistatin system with anthropometric parameters in offspring. PLoS ONE, 9(4):e92175.
PMID: 24763182 -
Species: Rat
Sample Types: Cell Culture Supernates
Chen L et al. (2014), Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells. Cell Commun Signal, 12(0):18.
PMID: 24628936 -
Species: Mouse
Sample Types: Serum
Pitetti J et al. (2013), An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice. Mol Endocrinol, 27(5):814-27.
PMID: 23518924 -
Species: Human
Sample Types: Plasma
Chen W et al. (2013), Activin A is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes. Cardiovasc Diabetol, 12(1):150.
PMID: 24134550 -
Species: Mouse
Sample Types: Cell Culture Supernates
Sierra-Filardi E et al. (2011), Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood, 117(19):5092-101.
PMID: 21389328 -
Species: Human
Sample Types: Serum
Rufo A et al. (2011), Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans. J. Bone Miner. Res., 26(8):1891-903.
PMID: 21509823 -
Species: Human
Sample Types: Plasma
Barrios-Silva L et al. (0), Activin subfamily peptides predict chronological age in humans. Physiol Re6(17):e13823.
PMID: 30178598
There are no citations that match your criteria.
Customer Reviews for Human/Mouse/Rat Activin A Quantikine ELISA Kit (10)
4.7 out of 5
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Sample Tested: Mouse serum samplesVerified Customer | Posted 07/27/2022
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Sample Tested: SerumVerified Customer | Posted 06/30/2022
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Sample Tested: Cell culture supernatantVerified Customer | Posted 11/06/2020
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Sample Tested: Cell culture supernatantVerified Customer | Posted 11/04/2020
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Sample Tested: Serum-free Cell Culture Media,T cellsVerified Customer | Posted 06/26/2020reliable product and easy to use
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Sample Tested: Serum and PlasmaVerified Customer | Posted 03/14/2019
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Sample Tested: Recombinant proteinVerified Customer | Posted 05/16/2017
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Sample Tested: SerumVerified Customer | Posted 05/03/2017
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Sample Tested: SerumVerified Customer | Posted 04/24/2017
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Sample Tested: Recombinant proteinVerified Customer | Posted 04/21/2017
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Product Documents for Human/Mouse/Rat Activin A Quantikine ELISA Kit
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
