Rat Abeta 42 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-53200

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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (50 uL)

Sensitivity

6.1 pg/mL (example only; lot dependent)

Assay Range

15.625 - 1000 pg/mL (example only; lot dependent)

View all Abeta 42 ELISA Kits »

Product Specifications

Assay Type

Competitive ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Rat

Description

Assay Length: 4.5 hours

Precision

Intra-Assay Precision (Precision within an assay) %CV < 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV < 12 (example only; lot dependent)

Scientific Data Images for Rat Abeta 42 ELISA Kit (Colorimetric)

Rat Abeta 42 ELISA Kit (Colorimetric) ELISA: Rat Abeta 42 ELISA Kit (Colorimetric) [NBP3-53200]

ELISA: Rat Abeta 42 ELISA Kit (Colorimetric) [NBP3-53200]

Kit Contents for Rat Abeta 42 ELISA Kit (Colorimetric)

  • Pre-coated 96T strip plate, Plate sealer for 96 wells, Standard, Diluent Buffer, Detection Reagent A, Detection Reagent B, TMB Substrate, Stop Solution, Wash Buffer (30 x concentrate), Instruction manual

Preparation and Storage

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Abeta 42

Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.

The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.

Mutations in Amyloid Precursor Protein (APP) that are associated with early-onset Alzheimer's have been shown to specifically increase the relative production of the Abeta42 isoform. Abeta 42 is also more fibrillogenic and plays a bigger role in deneurogeneration. It is therefore more strongly associated with Alzheimer's disease than Abeta 40.

Abeta42 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.

Alternate Names

Amyloid beta 42, Beta-amyloid protein 42

Gene Symbol

APP

Additional Abeta 42 Products

Product Documents for Rat Abeta 42 ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Rat Abeta 42 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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