5-Carboxylcytosine Antibody Pair [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23468

Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Reactivity

Human

View all 5-Carboxylcytosine ELISA Kits »

Product Specifications

Conjugate

Biotin

Kit Contents for 5-Carboxylcytosine Antibody Pair [Biotin]

  • Rabbit Monoclonal Adenine and Guanine Detection Antibody (Biotinylated)
  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP3-18829)

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: 5-Carboxylcytosine

5-carboxylcytosine (5caC) is the final oxidized derivative of 5-methylcytosine (5mC). 5mC is oxidized to 5-hydroxymethylcytosine (5hmC) which is then oxidized to 5-formylcytosine (5fC) then 5caC. Each of these oxidation steps are catalyzed by the Ten-Eleven Translocation (TET) family of enzymes. 5fC can then be further oxidized to 5-carboxylcytosine (5caC) by TET. Both 5fC and 5caC can be converted to unmodified cytosine by Terminal deoxynucleotidyl transferase (TdT) or Thymine DNA glycosylase (TDG) by base excision repair.

Alternate Names

5-caC

Additional 5-Carboxylcytosine Products

Product Documents for 5-Carboxylcytosine Antibody Pair [Biotin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 5-Carboxylcytosine Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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