Human TGF-beta 3 (NP_003230.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3655
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TGF-beta 3
TGF-beta 3 (transforming growth factor beta 3) Is a pleiotropic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. Disulfide-linked homodimers of LAP and TGF-beta 3 remain non-covalently associated after secretion, forming the small latent TGF-beta 3 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Bioactive TGF-beta is released by proteolytic cleavage. TGF-beta 3 signals through a receptor complex containing TGF-beta RII and either TGF-beta RI/ALK5 or ALK1.
Long Name
Transforming Growth Factor beta 3
Alternate Names
ARVD1, LDS5, RNHF, TGFB3, TGFbeta 3
Gene Symbol
TGFB3
UniProt
Additional TGF-beta 3 Products
Product Documents for Human TGF-beta 3 (NP_003230.1) VersaClone cDNA
Product Specific Notices for Human TGF-beta 3 (NP_003230.1) VersaClone cDNA
For research use only
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