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TGF-beta 3: Proteins and Enzymes
TGF-beta 3 (transforming growth factor beta 3) Is a pleiotropic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. Disulfide-linked homodimers of LAP and TGF-beta 3 remain non-covalently associated after secretion, forming the small latent TGF-beta 3 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Bioactive TGF-beta is released by proteolytic cleavage. TGF-beta 3 signals through a receptor complex containing TGF-beta RII and either TGF-beta RI/ALK5 or ALK1.
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TGF-beta 3: Proteins and Enzymes
TGF-beta 3 (transforming growth factor beta 3) Is a pleiotropic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. Disulfide-linked homodimers of LAP and TGF-beta 3 remain non-covalently associated after secretion, forming the small latent TGF-beta 3 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Bioactive TGF-beta is released by proteolytic cleavage. TGF-beta 3 signals through a receptor complex containing TGF-beta RII and either TGF-beta RI/ALK5 or ALK1.
2 results for "TGF-beta 3 Proteins and Enzymes" in Products
BA
A New and Improved rh TGF-beta 3 is Now Available! It is CHO-expressed and competitively priced.
| Source : | Sf 21 (baculovirus) |
| Accession # : | P10600 |
| Applications : | Bioactivity |
BA
| Source : | CHO |
| Accession # : | P10600 |
| Applications : | Bioactivity |
