Human SLITRK6 (NP_115605) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1784
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: SLITRK6
SLITRK6 (Slit and Trk-like family member 6) is a transmembrane protein that is expressed in multiple regions of the developing nervous system, notably in the otic vesicle, cochlear and vestibular sensory epithelia, and spiral vestibular ganglion neurons. It can suppress neurite outgrowth and promote the formation of excitatory and inhibitory presynaptic structures. Mice lacking SLITRK6 exhibit delayed retinal synaptogenesis and multiple auditory abnormalities as well as defective auditory sensory innervation, neuronal loss in the vestibular ganglia, and reduced cochlear expression of BDNF, NT-3, TrkB, and TrkC. In humans, nonsense mutations of SLITRK6 are associated with myopia and sensorial deafness.
Long Name
SLIT and NTRK-like Family, Member 6
Alternate Names
FLJ22774, MGC119595, MGC119596, MGC119597,4832410J21Rik, SLIT and NTRK-like family, member 6, SLIT and NTRK-like protein 6, slit and trk like gene 6
Gene Symbol
SLITRK6
UniProt
Additional SLITRK6 Products
Product Documents for Human SLITRK6 (NP_115605) VersaClone cDNA
Product Specific Notices for Human SLITRK6 (NP_115605) VersaClone cDNA
For research use only
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