Human LINGO-1 (NP_116197) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1089
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: LINGO-1
LINGO-1 (Leucine-rich repeat- and Ig domain-containing nogo receptor-interacting protein 1) is a transmembrane protein of the leucine-rich repeat (LRR) family, ribonuclease inhibitor subfamily. The four known LINGO proteins contain LRR and IgCAM domains in the extracellular portion and share 44-61% aa identity. LINGO-1 is restricted to the nervous system and is concentrated in the brain as a component of the NgR1/p75 and NgR1/Taj (Troy) signaling complexes. LINGO-1 negatively regulates neurite outgrowth and myelination, and is highly conserved, showing 99% aa identity between human, mouse and rat.
Long Name
Leucine-rich Repeat And Ig Domain Containing Nogo Receptor-Interacting Protein 1
Alternate Names
LERN1, LINGO1, LRRN6A
Entrez Gene IDs
84894 (Human)
Gene Symbol
LINGO1
UniProt
Additional LINGO-1 Products
Product Documents for Human LINGO-1 (NP_116197) VersaClone cDNA
Product Specific Notices for Human LINGO-1 (NP_116197) VersaClone cDNA
For research use only
Loading...
Loading...
Loading...