Human Connexin 50/GJA8 (NP_005258) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC0927

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Key Product Details

Species

Human

Accession Number

NP_005258

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Connexin 50/GJA8

The 433 amino acid long, 48 kDA transmembrane connexin, gap junction alpha-8 protein encoded by the GJA8 gene is critical in growth and development of lens fiber cells. Mutations in the GJA8 gene may lead to zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. The GJA8 gene has been linked to myopia, microphthalmia, neuronitis, cycstic fibrosis, neuopathy, cervical adenocarcinoma, and juvenile myoclonic epilepsy. The GJA8 gene interacts with TJP1, MIP, MED14, GJA1, and GJB1 to participate in pathways such as gap junction assembly, membrane trafficking, and connexin synthesis.

Alternate Names

CAE1, CX50, CZP1, GJA8, MP70

Entrez Gene IDs

2703 (Human); 14616 (Mouse)

Gene Symbol

GJA8

UniProt

NP_005258

Additional Connexin 50/GJA8 Products

Product Documents for Human Connexin 50/GJA8 (NP_005258) VersaClone cDNA

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Human Connexin 50/GJA8 (NP_005258) VersaClone cDNA

For research use only

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