Human beta-2 Adrenergic R/ADRB2 (NP_000015) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC0631
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: beta-2 Adrenergic R/ADRB2
ADRB2 is a member of the G protein-coupled receptor superfamily that is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. ADRB2 binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by ADRB2. Different polymorphic forms, point mutations, and/or downregulation of ADRB2 are associated with nocturnal asthma, obesity and type 2 diabetes.
Long Name
Beta-2 Adrenergic Receptor
Alternate Names
ADRB2, ADRB2R, B2AR, beta-2 AdrenergicR, beta2 AdrenergicR
Gene Symbol
ADRB2
UniProt
Additional beta-2 Adrenergic R/ADRB2 Products
Product Documents for Human beta-2 Adrenergic R/ADRB2 (NP_000015) VersaClone cDNA
Product Specific Notices for Human beta-2 Adrenergic R/ADRB2 (NP_000015) VersaClone cDNA
For research use only
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