Thymosin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-36979

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-36979
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Thymosin alpha 1/PTMA Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-DVDTKKQKTDEDD corresponding to C-Terminus according to NP_001092755.1, NP_002814.3.

Epitope

C Terminus

Reactivity Notes

Expected from sequence similarity: Rat, Dog

Specificity

This antibody is expected to recognize both reported isoforms (NP_001092755.1; NP_002814.3).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Novus Biologicals Goat Thymosin alpha 1 Antibody (NBP1-36979) is a polyclonal antibody validated for use in IHC and ELISA. Anti-Thymosin alpha 1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Thymosin alpha 1 Antibody

Immunohistochemistry-Paraffin: Thymosin alpha 1 Antibody [NBP1-36979]

Immunohistochemistry-Paraffin: Thymosin alpha 1 Antibody [NBP1-36979]

Immunohistochemistry-Paraffin: Thymosin alpha 1 Antibody [NBP1-36979] - (3.75ug/ml) staining of Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for Thymosin alpha 1 Antibody

Application
Recommended Usage

Immunohistochemistry

3.75 ug/ml

Peptide ELISA

Detection limit 1:1000
Application Notes
WB: Preliminary experiments gave an approx. 38 kDa band in lysates of A431 after 0.2 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 12.2 kDa band according to NP_001092755.1 and of 12.1 kDa band according to NP_002814.3. The 38 kDa band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Thymosin alpha 1/PTMA

Thymosin alpha 1 is a protein that helps mediate immune function by conferring resistance to various infections, and has two isoforms, with lengths of 111 and 110 amino acids and both weighing approximately 12 kDa. Current studies are being done on several diseases and disorders related to this protein including severe acute respiratory syndrome, myasthenia gravis, chronic obstructive pulmonary disease, hepatitis, liver cirrhosis, male infertility, thymoma, pituitary adenoma, hepatocellular carcinoma, hepatoblastoma, sepsis, tonsillitis, gastric adenocarcinoma, and breast cancer. Thymosin alpha 1 has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the C-MYC transcriptional activation pathway.

Alternate Names

PTMA, Thym, TMSA

Entrez Gene IDs

5757 (Human); 500448 (Rat)

Gene Symbol

PTMA

UniProt

NP_001092755.1 (Human)

Additional Thymosin alpha 1/PTMA Products

Product Documents for Thymosin alpha 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Thymosin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.