SHIP Antibody (257812) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # FAB2317E

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

MAB2317

Allophycocyanin

FAB2317A

Biotin

FAB2317B

CoraFluor 1

FAB2317CL1

DyLight 350

FAB2317D

DyLight 488

FAB2317K

DyLight 550

FAB2317L

DyLight 594

FAB2317M

DyLight 650

FAB2317W

DyLight 680

FAB2317Y

DyLight 755

FAB2317Z

FITC

FAB2317F

HRP

FAB2317H

Janelia Fluor 525

FAB2317JF525

Janelia Fluor 549

FAB2317I

Janelia Fluor 646

FAB2317J

Janelia Fluor 669

FAB2317JF669

mFluor Violet 450 SE

FAB2317MFV450

mFluor Violet 500 SE

FAB2317MFV500

mFluor Violet 610 SE

FAB2317MFV610

PE

FAB2317P

PerCP

FAB2317C

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry, Knockout Validated, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Rat IgG_2A Clone # 257812

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SHIP Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse SHIP
Glu874-Thr941
Accession # Q9ES52

Specificity

Detects human, mouse, and rat SHIP in Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG_2A

Applications for SHIP Antibody (257812) [DyLight 405]

Application

Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Knockout Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SHIP

SH2-containing inositol phosphatase 1 (SHIP) is a 145 kDa hemopoietic-specific phosphatase that hydrolyzes phosphatidylinositol-3,4,5-triphosphate to phosphatidylinositol-3, 4-bisphosphate. SHIP has been shown to bind directly a phosphorylated motif, immunoreceptor tyrosine-based inhibition motif (ITIM), present in the cytoplasmic domain of FcgammaRIIB1 (1). Also, results demonstrate that FcgammaRIIB use SHIP1 to inhibit pathways shared by receptor tyrosine kinases and immunoreceptors to trigger cell proliferation and cell activation, respectively (2).

Long Name

SH2-containing Inositol Phosphatase

Alternate Names

INPP5D

Gene Symbol

INPP5D

Additional SHIP Products

Product Documents for SHIP Antibody (257812) [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for SHIP Antibody (257812) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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