PAR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-44306

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NBP1-44306
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Primate (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PAR2 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from 2nd extracellular domain of human PAR2.

Epitope

2nd extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (94%), Gorilla (89%), Equine (89%), Porcine (89%).

Specificity

Human PAR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NMBR (39%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PAR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: PAR2 Antibody - BSA Free [NBP1-44306]

Immunohistochemistry-Paraffin: PAR2 Antibody - BSA Free [NBP1-44306]

Immunohistochemistry-Paraffin: PAR2 Antibody [NBP1-44306] - Analysis of anti-F2RL1 antibody with human kidney.

Applications for PAR2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID 27457091)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PAR2

The Proteinase-activated receptor 2 (PAR2) is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. ESTs have been isolated from adrenal, brain, breast, heart/melanocyte/uterus, kidney, lung, and vessel libraries.

Long Name

Protease-Activated Receptor 2

Alternate Names

CFIIRL1, F2RL1, GPCR11

Gene Symbol

F2RL1

Additional PAR2 Products

Product Documents for PAR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PAR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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