P2X7/P2RX7 Antibody (CL11508) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21196

Novus Biologicals, part of Bio-Techne
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NBP3-21196-25ul
NBP3-21196-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL11508

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all P2X7/P2RX7 Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q99572, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Rat (85%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Description

Novus Biologicals Mouse P2X7/P2RX7 Antibody (CL11508) - BSA Free (NBP3-21196) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Analysis in human cell line SK-MEL-30.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebral cortex shows moderate positivity in neuronal processes in neuropil.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebellum shows strong positivity in neuronal processes in neuropil.
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Applications for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500- 1:1000

Immunohistochemistry-Paraffin

1:500- 1:1000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X7/P2RX7

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Long Name

P2X Purinergic Receptor 7

Alternate Names

P2RX7

Gene Symbol

P2RX7

Additional P2X7/P2RX7 Products

Product Documents for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for P2X7/P2RX7 Antibody (CL11508) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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