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P2X7/P2RX7 Antibody (CL11508) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21196

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NBP3-21196-25ul
NBP3-21196-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL11508

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q99572, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Rat (85%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Analysis in human cell line SK-MEL-30.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebral cortex shows moderate positivity in neuronal processes in neuropil.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebellum shows strong positivity in neuronal processes in neuropil.

Applications for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500- 1:1000

Immunohistochemistry-Paraffin

1:500- 1:1000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X7/P2RX7

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Long Name

P2X Purinergic Receptor 7

Alternate Names

P2RX7

Gene Symbol

P2RX7

Additional P2X7/P2RX7 Products

Product Documents for P2X7/P2RX7 Antibody (CL11508) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for P2X7/P2RX7 Antibody (CL11508) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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