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P11 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46927

Novus Biologicals, part of Bio-Techne
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NBP3-46927

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

26 serine protease. (Uniprot# P21128)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit P11 Antibody - BSA Free (NBP3-46927) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for P11 Antibody - BSA Free

P11 Antibody - BSA Free

Western Blot: P11 Antibody - BSA Free [NBP3-46927] -

Western Blot: P11 Antibody - BSA Free [NBP3-46927] - Mouse lung tissue were subjected to SDS PAGE followed by western blot with (P11 antibody) at dilution of 1:600
P11 Antibody - BSA Free

Immunohistochemistry: P11 Antibody - BSA Free [NBP3-46927] -

Immunohistochemistry: P11 Antibody - BSA Free [NBP3-46927] - Immunohistochemistry of paraffin-embedded human breast cancer using (P11 antibody) at dilution of 1:100

Applications for P11 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:5000
Application Notes
Theoretical Molecular Weight is 35-40 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: P11

p11 increases localization of 5-HT1B receptors at the cell surface. It is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients. Overexpression of p11 increases 5-HT1B receptor function in cells and recapitulates certain behaviors seen after antidepressant treatment in mice. p11 knockout mice exhibit a depression-like phenotype and have reduced responsiveness to 5-HT1B receptor agonists and reduced behavioral reactions to an antidepressant.

Alternate Names

EC 3.1, endonuclease, polyU-specific, MGC133268, P11,26 serine protease, Placental protein 11, poly(U)-specific endoribonuclease, PP1122 serine protease, Protein endoU, PRSS26, Uridylate-specific endoribonuclease

Gene Symbol

ENDOU

Additional P11 Products

Product Documents for P11 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for P11 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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