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OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44024

Novus Biologicals, part of Bio-Techne
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NBP3-44024

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3771

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of Q9NPD5, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free (NBP2-61637) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free

OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP3-44024]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP3-44024]

Staining of human liver shows strong membranous immunoreactivity in hepatocytes.
OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP3-44024]

Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody [NBP3-44024]

Staining of human skeletal muscle shows absence of immunoreactivity (negative control).

Applications for OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500 - 1:10000
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OATP1B3/SLCO1B3

The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.

Long Name

Sodium-independent Organic Anion-transporting Polypeptide 2

Alternate Names

LST2, LST3, OATP8, SLC21A8, SLCO1B3

Gene Symbol

SLCO1B3

Additional OATP1B3/SLCO1B3 Products

Product Documents for OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for OATP1B3/SLCO1B3/OATP8 Antibody (CL3771) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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