MRP3 Antibody (M3II-9)
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-42347
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence
Cited:
Immunohistochemistry-Paraffin, Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # M3II-9
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Product Specifications
Immunogen
MRP3 (aa 830-949)
Specificity
Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Description
The concentration of this material is approximately 0.25mg immunoglobulin/ml.
Scientific Data Images for MRP3 Antibody (M3II-9)
Immunohistochemistry: MRP3 Antibody (M3II-9) [NBP1-42347] -
MRP3 expression in GSCs under hypoxic conditions. (A) MRP3 protein levels from GSCs under normoxia and hypoxia were analyzed by Western blot of GSCs. Bands were quantified and plotted. beta-actin was used as a housekeeping control. (B) MRP3 expression was detected in human GBM samples by immunohistochemistry (scale bar 50 m). (C) Histograms represent fluorescence of CFDA accumulation (left) and plotted as fold of change of fluorescence (right). n = 3, * p < 0.05, ** p < 0.01, **** p < 0.0001, # p < 0.05 relative to hypoxia control. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/36012307), licensed under a CC-BY license. Not internally tested by Novus Biologicals.Applications for MRP3 Antibody (M3II-9)
Application
Recommended Usage
Flow Cytometry
1:10-1:1000
Immunocytochemistry/ Immunofluorescence
1:10-1:500
Immunohistochemistry
1:10-1:500
Immunohistochemistry-Frozen
1:10-1:500
Western Blot
1:100-1:2000
Application Notes
M3II-9 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples. Immnocytochemistry: use 1:20-1:50 dil. on acetone or formaldehyde fixed cytospin preparations.
Formulation, Preparation, and Storage
Purification
Tissue culture supernatant
Formulation
Supernatant, 0.7% BSA
Preservative
0.1% Sodium Azide
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: MRP3
Long Name
ATP-binding cassette sub-family C member 3
Alternate Names
ABCC3, CMOAT2, EC 7.6.2.3, MLP2, MOAT-D
Gene Symbol
ABCC3
Additional MRP3 Products
Product Documents for MRP3 Antibody (M3II-9)
Product Specific Notices for MRP3 Antibody (M3II-9)
The concentration of this material is approximately 0.25mg immunoglobulin/ml.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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