Mouse Tryptase beta-1/MCP-7/Mcpt7 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF1937
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Mouse
Applications
Validated:
Western Blot
Cited:
ELISA Development (Detection)
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Tryptase beta‑1/MCP‑7/Mcpt7
Ile29-Phe273
Accession # Q02844
Ile29-Phe273
Accession # Q02844
Specificity
Detects mouse Tryptase beta‑1/MCP‑7/Mcpt7 in Western blots. In Western blots, less than 1% cross‑reactivity with recombinant mouse MCPT1 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Mouse Tryptase beta-1/MCP-7/Mcpt7 Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Mouse Tryptase beta-1/MCP-7/Mcpt7 (Catalog # 1937-SE)
Sample: Recombinant Mouse Tryptase beta-1/MCP-7/Mcpt7 (Catalog # 1937-SE)
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Tryptase beta-1/MCP-7
Tryptase beta-1 is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7 (1). It is stored in the secretory granules of mouse mast cells (2). It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma (3). The deduced amino acid sequence for mouse Tryptase beta-1 consists of a signal peptide (residues 1‑18), a pro region (residues 19‑28) and the mature chain (residue 29‑273). The mature chain was expressed and purified.
References
- McNeil, H.P. et al. (1992) Proc. Natl. Acad. Sci. USA 89:11174.
- Matsumoto, R et al. (1995) J. Biol. Chem. 270:19524.
- Huang, C. et al. (1997) J. Biol. Chem. 272:31885.
Long Name
Mast Cell Protease 7
Alternate Names
Mast Cell Tryptase, MCP-7, Mcp7, Mcpt7, TPSB1, TRYB1, Tryptase beta1
Entrez Gene IDs
100503895 (Mouse)
Gene Symbol
TPSAB1
UniProt
Additional Tryptase beta-1/MCP-7 Products
Product Documents for Mouse Tryptase beta-1/MCP-7/Mcpt7 Biotinylated Antibody
Product Specific Notices for Mouse Tryptase beta-1/MCP-7/Mcpt7 Biotinylated Antibody
For research use only
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