Mouse Trypsin 3/PRSS3 Alexa Fluor™ Plus 488-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB35651AFP488
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 419910
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Trypsin 3/PRSS3
Specificity
Detects mouse Trypsin 3/PRSS3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, weak cross-reactivity with recombinant human (rh) Trypsin 3 is observed and no cross-reactivity with rhTrypsin 1 or rhTrypsin 2 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Applications
Application
Recommended Usage
Western Blot
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: Trypsin 3/PRSS3
Trypsin 3, encoded by the PRSS3 gene and also known as mesotrypsin is a serine protease and is one of three pancreatic Trypsins. It constitutes less than 10% of the total Trypsin content in normal pancreatic juice. Trypsin 3 is activated by enterokinase cleavage of the 8 aa pro region and secreted into the duodenum lumen. Trypsin 3 is highly resistance to polypeptide Trypsin inhibitors, and may degrade them in foods to facilitate digestion. The 223 amino acid mature mouse Trypsin 3 shares 78% and 96% aa identity with human and rat Trypsin 3, respectively.
Alternate Names
Mesotrypsin, MTG, PRSS3, PRSS4, Trypsin 4, Trypsinogen 15
Gene Symbol
PRSS3
UniProt
Additional Trypsin 3/PRSS3 Products
Product Specific Notices
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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