Mouse CD5 Alexa Fluor™ Plus 405-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB115AFP405
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Immunohistochemistry, Flow Cytometry, Immunoprecipitation, Complement-dependent Cytotoxicity, Blocking B Cell Proliferation, CyTOF-reported
Label
Alexa Fluor Plus 405 (Excitation = 404 nm, Emission = 455 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 53-7.3
Product Specifications
Immunogen
Mouse thymus or spleen
Specificity
Detects mouse CD5.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse CD5 Alexa Fluor™ Plus 405-conjugated Antibody
Application
Recommended Usage
Blocking B Cell Proliferation
Optimal dilution of this antibody should be experimentally determined.
Complement-dependent Cytotoxicity
Optimal dilution of this antibody should be experimentally determined.
CyTOF-reported
Optimal dilution of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilution of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
Immunoprecipitation
Optimal dilution of this antibody should be experimentally determined.
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Formulation, Preparation, and Storage
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
Background: CD5
Mouse CD5 has been shown to react with a mouse monomorphic CD5 (Ly-1), a Group B member of the scavenger receptor cysteine-rich protein superfamily (1). CD5 is a 67 kDa type I transmembrane glycoprotein found on thymocytes, T cells, and a subset of B cells but not on NK cells (2‑6). It is likely a ligand of the B cell differentiation antigen CD72 and is known to associate with CD6 (1). Mouse and human extracellular domains share 55% amino acid sequence indentity.
References
- Martinez, V.G., et al. (2011) Pharmacol. Rev. 63:967.
- Ledbetter, J.A. et al. (1980) J. Exp. Med. 152:280.
- van Ewijk, W. et al. (1981) J. Immunol. 127:2594.
- Hayakawa, K. et al. (1983) J. Exp. Med. 157:202.
- Luo, W. et al. (1992) J. Immunol. 148:1630.
- Lanier, L.L. et al. (1986) J. Immunol. 137:2735.
Alternate Names
CD5
Gene Symbol
CD5
Additional CD5 Products
Product Specific Notices for Mouse CD5 Alexa Fluor™ Plus 405-conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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